KEGG   Streptococcus pneumoniae gamPNI0373 (virulent serotype 1): HMPREF1038_00488
Entry
HMPREF1038_00488  CDS       T02334                                 
Symbol
ilvC
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
spng  Streptococcus pneumoniae gamPNI0373 (virulent serotype 1)
Pathway
spng00290  Valine, leucine and isoleucine biosynthesis
spng00770  Pantothenate and CoA biosynthesis
spng01100  Metabolic pathways
spng01110  Biosynthesis of secondary metabolites
spng01210  2-Oxocarboxylic acid metabolism
spng01230  Biosynthesis of amino acids
Module
spng_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
spng_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:spng00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HMPREF1038_00488 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    HMPREF1038_00488 (ilvC)
Enzymes [BR:spng01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     HMPREF1038_00488 (ilvC)
SSDB
Motif
Pfam: KARI_N KARI_C 2-Hacid_dh_C F420_oxidored AdoHcyase_NAD NAD_binding_2 ApbA NAD_Gly3P_dh_N DUF1103 CoA_binding TrkA_N DUF7779
Other DBs
NCBI-ProteinID: AFS42561
LinkDB
Position
432770..433792
AA seq 340 aa
MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDVIIGVRPGKSFDKAKED
GFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGNAVGFAHGFNIHFEFIKVP
ADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGNAKNIAMDWCKGVGAARVGLL
ETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAGYAPELAYFEVLHEMKLIVDLIY
EGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMKAVLADIQNGKFANDFVNDYKAGRP
KLTAYREQAANLEIEKVGAELRKAMPFVGKNDDDAFKIYN
NT seq 1023 nt   +upstreamnt  +downstreamnt
atgacagttcaaatggaatatgaaaaagatgttaaagtagcagcacttgacggtaaaaaa
atcgccgttatcggttatggttcacaagggcatgcgcatgctcaaaacttgcgtgattcc
ggtcgtgacgttattatcggtgtacgtccaggtaaatcttttgataaagcaaaagaagat
ggatttgatacttacacagtagcagaagctactaagttggctgatgttatcatgatcttg
gcgccagacgaaattcaacaagaattgtacgaagcagaaatcgctccaaacttggaagct
ggaaacgcagttggatttgcccatggtttcaacatccactttgaatttatcaaagttcct
gcggatgtagatgtcttcatgtgtgctcctaaaggaccaggacacttggtacgtcgtact
tacgaagaaggatttggtgttccagctctttatgcagtataccaagatgcaacaggaaat
gctaaaaacattgctatggactggtgtaaaggtgttggagcggctcgtgtaggtcttctt
gaaacaacttacaaagaagaaactgaagaagatttgtttggtgaacaagctgtactttgt
ggtggtttgactgcccttatcgaagcaggtttcgaagtcttgacagaagcaggttacgct
ccagaattggcttactttgaagttcttcacgaaatgaaattgatcgttgacttgatctac
gaaggtggattcaagaaaatgcgtcaatctatttcaaacactgctgaatacggtgactat
gtatcaggtccacgtgtaatcactgaacaagttaaagaaaatatgaaggctgtcttggca
gacatccaaaatggtaaatttgcaaatgactttgtaaatgactataaagctggacgtcca
aaattgactgcttaccgtgaacaagcagctaaccttgaaattgaaaaagttggtgcagaa
ttgcgtaaagcaatgccattcgttggtaaaaacgacgatgatgcattcaaaatctataac
taa

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