Streptococcus pneumoniae gamPNI0373 (virulent serotype 1): HMPREF1038_02142
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Entry
HMPREF1038_02142 CDS
T02334
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
spng
Streptococcus pneumoniae gamPNI0373 (virulent serotype 1)
Pathway
spng00290
Valine, leucine and isoleucine biosynthesis
spng00770
Pantothenate and CoA biosynthesis
spng01100
Metabolic pathways
spng01110
Biosynthesis of secondary metabolites
spng01210
2-Oxocarboxylic acid metabolism
spng01230
Biosynthesis of amino acids
Module
spng_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
spng_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
spng00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HMPREF1038_02142 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
HMPREF1038_02142 (ilvD)
Enzymes [BR:
spng01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
HMPREF1038_02142 (ilvD)
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
AFS44106
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Position
complement(1947207..1948910)
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AA seq
567 aa
AA seq
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MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVISTWAENTPCNIHLHDFG
KLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDIIADSIEAAMSGHNVDAFV
AIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKDIDLVSVFEGIGKWNHGDMTA
EDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLPGSSSHPAESADKKEDIEAAGRA
VVKMLELGLKPSDILTREAFEDAITVTMALGGSTNATLHLLAIAHAANVDLSLEDFNTIQ
ERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLLANGFLHGDRITCTGKTVAENLADFAD
LTPGQKVIMPLENPKRADGPLIILNGNLAPDGAVAKVSGVKVRRHVGPAKVFDSEEDAIQ
AVLTDEIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGL
VVGHIAPEAQDGGPIAYLRTGDIVTVDQDTKEISMAVSEEELEKRKAETTLPPLYSRGVL
GKYAHIVSSASRGAVTDFWNMDKSGKK
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgactgaattagataaacgtcaccgcagtagcatttatgacagcatggttaaatcacct
aaccgtgctatgcttcgtgcgactggtatgacagataaggactttgaaacaccgattgtg
ggagtgatttcgacttgggcggaaaatacaccatgtaacattcacttgcatgatttcggg
aaactggctaaagaaggtgtcaaatctgcaggcgcttggcctgtacagtttggaaccatt
accgtagcggacgggatcgctatgggaacacctggtatgcgtttctctctaacatctcgt
gacatcatcgcggactccatcgaggcggctatgagtggtcacaacgtggatgccttcgtc
gctatcggtggctgtgacaagaacatgcctggatctatgattgctattgctaatatggat
atcccagccattttcgcctatggtggaactattgcaccgggaaatcttgatggtaaagat
atcgacttggtttctgtctttgaaggtatcggaaaatggaaccacggtgatatgacagct
gaggacgtgaaacgtcttgaatgtaatgcctgccctggccctggtggttgtggtggtatg
tatactgctaataccatggcaactgctatcgaagttctagggatgagtttgccagggtca
tcctctcacccagctgaatcagctgataagaaagaagatatcgaagcagcaggacgtgct
gttgttaagatgttggaacttggtctcaaaccatcagatatcttgactcgtgaagccttt
gaagatgctatcactgtaacgatggctctcggtggttctacaaacgccactcttcacttg
ctcgccattgcccatgccgcaaatgttgacttgtcacttgaggacttcaatacgattcaa
gaacgtgtgcctcacttggccgacttgaaaccatctggtcagtatgtcttccaagacctc
tacgaagtcggtggtgtccctgcggttatgaagtacttgttggcaaatggtttccttcac
ggagatcgcatcacatgtactggtaagactgtagctgaaaacttggctgactttgcagac
ttgactccaggccaaaaagttatcatgccacttgaaaatccaaaacgtgcggatggtccg
cttatcatcttgaacgggaaccttgctcctgacggtgcagttgccaaggtatcaggtgtt
aaagtgcgtcgtcacgttgggccagctaaggtctttgactcagaagaagatgcgattcag
gccgtcctgacagatgaaatcgttgatggcgatgtagtcgttgttcgttttgttggacct
aaaggtggtcctggtatgcctgagatgctgtcactttcttcaatgattgttggtaaaggt
cagggagataaggtggctctcttgacggacggacgtttctctggtggtacttatggtctg
gttgttggacatatcgctcctgaagctcaggatggtggaccaattgcctatctccgtacc
ggcgatatcgttacggttgaccaagataccaaagaaatttccatggccgtatccgaagaa
gaacttgaaaaacgcaaggcagaaacaaccttgccaccactttacagccgtggtgtcctc
ggtaaatatgcccacatcgtatcatctgcttcacgcggagccgtgacagacttctggaat
atggacaagtcaggtaaaaaataa
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