Streptococcus pneumoniae SPN994038 (serotype 3): SPN994038_00950
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Entry
SPN994038_00950 CDS
T02630
Symbol
purH
Name
(GenBank) bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase]
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
spnm
Streptococcus pneumoniae SPN994038 (serotype 3)
Pathway
spnm00230
Purine metabolism
spnm00670
One carbon pool by folate
spnm01100
Metabolic pathways
spnm01110
Biosynthesis of secondary metabolites
Module
spnm_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spnm00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPN994038_00950 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SPN994038_00950 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
spnm04147
]
SPN994038_00950 (purH)
Enzymes [BR:
spnm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
SPN994038_00950 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
SPN994038_00950 (purH)
Exosome [BR:
spnm04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
SPN994038_00950 (purH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
CCP29831
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All DBs
Position
86530..88077
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AA seq
515 aa
AA seq
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MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGVDTIAIDDVTGFPEMMD
GRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNLYPFKETILKPDVTYADAV
ENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAANGETSYETRQRLAAKVFRHTA
AYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENPQQDADFYQKALPTDYSIASAKQ
LNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHMNPCGIGQADDIETAWDYAYESDPV
SIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSYTDEALAILINKKKNLRILALPFNAQE
ASEVEAEYTGVVGGLLVQNQDVVKESPADWQVVTKRQPTETEATALEFAWKAIKYVKSNG
IIVTNDHMTLGVGPGQTNRVASVRLAIDQAKDRLDGAVLASDAFFPFADNVEEIAKAGIK
AIIQPGGSVRDQESIEAANKYGLTMVFTGVRHFRH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgactaaacgcgtcttaatcagcgtctcagacaaagcgggcattgttgaatttgcccaa
gaactcaaaaaacttggttgggagattatctcaacaggtggaactaaggttgcccttgat
aatgctggggtggataccattgctatcgatgatgtgactggtttcccagaaatgatggac
ggtcgtgtgaagaccctccacccaaatatccacggagggcttctcgctcgtcgtgacttg
gatagccacttggaagcggctaaggacaacaagattgagctcattgaccttgtggtggtc
aacctttacccatttaaggaaactatccttaaaccagatgtgacttatgctgatgcagtt
gaaaatatcgatattggtgggccgtctatgcttcgttcagcagcgaaaaatcatgccagt
gttacagttgtggtagatcctgctgactacgctgtggttttggacgaattggcagcaaac
ggcgaaacctcttatgaaactcgccaacgtttagcagccaaagtatttcgtcacacagcg
gcttatgacgccttgattgcagaatacttcacagctcaagtgggtgaaagcaagcctgaa
aaactcactttgacttatgacctcaagcaaccaatgcgttacggtgagaatcctcaacaa
gacgcggacttttaccagaaagctttgcctacagattactctattgcttcagccaaacag
ctcaacgggaaagaattgtcatttaataatatccgtgatgcagatgctgctatccgtatc
atccgtgacttcaaagatagtccaaccgttgtggctctcaaacacatgaatccatgtgga
attggtcaagctgatgacatcgagactgcttgggactacgcttatgagtctgacccagtg
tctatctttggtggaattgtcgtcctcaaccgtgaggtggatgctgcgacagctgagaag
atgcacggcgttttcctcgaaatcatcattgcaccaagctatacggatgaagcgctagcc
attttgatcaataaaaagaaaaacttgcgtatccttgccttgccatttaatgctcaagag
gctagcgaagtggaagcagaatacacaggtgtagtcggtggacttctcgtgcaaaatcaa
gacgtggtcaaggaaagcccagctgactggcaagtggtgaccaaacgtcagccaaccgag
acagaagcgactgctcttgagttcgcttggaaggctatcaagtacgtcaaatcaaatggt
attatcgtgaccaacgaccacatgacacttggtgttggtccaggtcaaaccaaccgtgtg
gcttctgttcgccttgccattgaccaagccaaagatcgtctggacggggcggtccttgct
tcagatgccttcttcccatttgcggataacgtggaagaaatcgccaaagcaggaattaag
gccatcatccagcccggtggctctgtccgtgaccaagaatccatcgaagcagcgaataaa
tacggcttgactatggtctttacaggtgtgagacattttagacattaa
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