Schizosaccharomyces pombe (fission yeast): 2541003
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Entry
2541003 CDS
T00076
Symbol
leu3, SPOM_SPBC3E7.16C
Name
(RefSeq) 2-isopropylmalate synthase Leu3
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
spo
Schizosaccharomyces pombe (fission yeast)
Pathway
spo00290
Valine, leucine and isoleucine biosynthesis
spo00620
Pyruvate metabolism
spo01100
Metabolic pathways
spo01110
Biosynthesis of secondary metabolites
spo01210
2-Oxocarboxylic acid metabolism
spo01230
Biosynthesis of amino acids
Module
spo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
spo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
2541003 (leu3)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
2541003 (leu3)
Enzymes [BR:
spo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
2541003 (leu3)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
TLC
Motif
Other DBs
NCBI-GeneID:
2541003
NCBI-ProteinID:
NP_596103
PomBase:
SPBC3E7.16c
SPBC3E7.16c.1
UniProt:
O59736
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Position
II:complement(2688592..2690346)
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AA seq
584 aa
AA seq
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MKSTFEAAGRVAKGMLKDPSKKYKPFKGIQLPNRQWPNKVLTKAPRWLSTDLRDGNQALP
DPMNGQEKLRYFKLLCSIGFKEIEVGFPSASQTDFAFVRHLIETPGLIPDDVTISALTPS
REPLILRTIEALRGAKNATVHLYNACSPLFREVVFRNSKQETLDLAIKGSKIVTAATKNA
LESKETNWGFEYSPETFSDTEPDFALEVCEAVKGMWKPSAAQPIIFNLPATVEMSTPNTY
ADLIEYFSTNISEREKVCVSLHPHNDRGTAVAAAELGQLAGGDRIEGCLFGNGERTGNVD
LVTLAFNLYTQGVSPNLDFSKLDEIIRITEDCNKINVHPRHPYAGNLVFTAFSGSHQDAI
SKGLKAYDERKAVDPVWKVPYLPLDPHDVNSEYAAIIRVNSQSGKGGVAYLLKTNCGLDL
PRALQVEFGSIVKDYSDTKGKELSIGEISDLFYTTYYLEFPGRFSVNDYTLSSNGPQSKC
IKCVVDIKGEKKDTPSRVVIEGVGNGPLSALVDALRRQFNISFDIGQYSEHAIGSGNGVK
AASYVEIIFNNTSFWGVGIDADVTSAGLKAVMSGVSRASRAFAK
NT seq
1755 nt
NT seq
+upstream
nt +downstream
nt
atgaaatctacttttgaggctgctggccgcgttgccaaagggatgctcaaggatccctcc
aaaaagtataagccatttaaaggaattcaactacccaaccgtcaatggccaaacaaggtt
ttgacgaaagctccacgctggctttctacggacttgcgtgatggtaatcaggctttaccc
gatcctatgaatgggcaggagaaattgagatattttaaattgctttgcagtattggcttc
aaagaaattgaggttggtttcccaagtgcttctcaaactgattttgcatttgttcgtcat
ctgattgaaacgccaggtttgattcctgacgatgttactatttctgcccttactccttct
cgtgagcctttgatcctacgtacgattgaggctcttcgaggcgctaagaatgccactgtt
cacttgtataatgcctgttctcctcttttccgtgaagttgtcttccgcaacagtaagcaa
gaaacattggatttagccatcaaaggctcaaaaatcgtaacagctgctacgaaaaatgct
cttgaatcgaaggaaaccaactggggatttgaatattctcctgaaactttttcagacacc
gaaccagactttgctttggaagtttgtgaagctgtcaagggtatgtggaaaccttctgct
gcccaacctattatcttcaatcttcctgccactgtcgaaatgtctacgcccaacacatat
gctgacttaattgagtacttttccactaacattagtgaacgtgaaaaagtctgtgtttct
ctccatccccataacgaccgtggtactgctgtcgcagcagctgaacttggtcaacttgcc
ggaggtgaccgtattgagggctgtttgtttggcaatggtgaacgtactggtaatgtagac
ttggttactttggctttcaacttgtatacccaaggtgtttctcctaacctcgatttctcc
aagttggatgaaatcattcgtattactgaagactgtaacaagataaacgttcatccccgt
catccttatgctggcaatcttgtctttaccgccttttctggttctcatcaagatgccatt
tctaagggtttgaaggcttacgatgagcgtaaagctgtcgatcctgtttggaaagtccct
tacttgcctttggatccccatgatgtcaattccgagtatgctgctattatccgcgttaac
tctcaatctggcaagggtggtgtcgcatatctgttgaagaccaactgtggtctcgattta
cctcgtgctttgcaagttgaatttggtagtattgttaaggattatagcgacacaaaagga
aaggagcttagcattggtgagatcagcgacctgttttataccacatattacctcgaattt
cccggccgtttctctgtaaacgactacactctttctagcaacggacctcaaagcaaatgt
attaaatgcgttgttgacatcaagggtgaaaagaaagatactccttcgcgggttgtgatc
gagggtgttggaaatggacctttgtcggcattggttgatgctttacgccgtcagttcaat
atttcatttgacattggtcaatactctgaacatgctattggttctggtaacggcgtcaaa
gctgcttcttatgttgagatcattttcaataacacttctttctggggtgttggtattgat
gctgacgttacctctgccggattaaaggctgtcatgtcaggcgttagtcgtgcctcccgc
gcatttgctaagtaa
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