KEGG   Schizosaccharomyces pombe (fission yeast): 2542757
Entry
2542757           CDS       T00076                                 
Symbol
mre11, SPOM_SPAC13C5.07
Name
(RefSeq) Mre11 nuclease
  KO
K10865  double-strand break repair protein MRE11
Organism
spo  Schizosaccharomyces pombe (fission yeast)
Pathway
spo03440  Homologous recombination
spo03450  Non-homologous end-joining
Brite
KEGG Orthology (KO) [BR:spo00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    2542757 (mre11)
   03450 Non-homologous end-joining
    2542757 (mre11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:spo03032]
    2542757 (mre11)
   03400 DNA repair and recombination proteins [BR:spo03400]
    2542757 (mre11)
DNA replication proteins [BR:spo03032]
 Eukaryotic type
  DNA Replication Termination Factors
   MRN complex
    2542757 (mre11)
DNA repair and recombination proteins [BR:spo03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    MRN(MRX) complex
     2542757 (mre11)
    BRCA1-C complex
     2542757 (mre11)
   NHEJ (non-homologous end-joining)
    MRX complex
     2542757 (mre11)
SSDB
Motif
Pfam: Mre11_DNA_bind Metallophos Metallophos_2
Other DBs
NCBI-GeneID: 2542757
NCBI-ProteinID: NP_592935
PomBase: SPAC13C5.07 SPAC13C5.07.1
UniProt: Q09683
Structure
LinkDB
Position
I:join(436214..436381,436430..436935,437006..437580,437624..437807,437853..438369)
AA seq 649 aa
MPNDPSDMNNELHNENTIRILISSDPHVGYGEKDPVRGNDSFVSFNEILEIARERDVDMI
LLGGDIFHDNKPSRKALYQALRSLRLNCLGDKPCELELLSDTSLTTGDTAVCNINYLDPN
INVAIPVFSIHGNHDDPSGDGRYSALDILQVTGLVNYFGRVPENDNIVVSPILLQKGFTK
LALYGISNVRDERLYHSFRENKVKFLRPDLYRDEWFNLLTVHQNHSAHTPTSYLPESFIQ
DFYDFVLWGHEHECLIDGSYNPTQKFTVVQPGSTIATSLSPGETAPKHCGILNITGKDFH
LEKIRLRTVRPFIMKDIILSEVSSIPPMVENKKEVLTYLISKVEEAITEANAQWYEAQGT
VPVVENEKPPLPLIRLRVDYTGGYQTENPQRFSNRFVGRVANATDVVQFYLKKKYTRSKR
NDGLYTSAVEDIKINSLRVESLVNEYLKTNRLECLPEDSLGEAVVNFVEKDDRDAIKECV
ETQLNKQINLLVKKRVTEENLEQEISSIINDLPKISTTKRKDYEELPEEVSETSINIAEH
TPVLKHTSSLLDHHSPLATSSSEHEMEATPSPALLKKTNKRRELPSSLTKKNTRTPQRSK
EVKKVPARKLSQSTKKSDKNTQSTLLFYDPSSTTEAQYLDNEDDEILDD
NT seq 1950 nt   +upstreamnt  +downstreamnt
atgccaaatgacccctcagatatgaataatgaacttcataatgaaaatactattagaatc
ttaatatcttctgacccacatgtgggatatggggagaaagatcctgttcgtggtaacgat
tcctttgttagtttcaacgaaattttagaaattgctcgtgaaagagatgtggatatgatt
ttgttaggcggtgatatatttcatgacaacaaaccgtcaagaaaggctttgtatcaagca
cttcgctcactcagattaaactgtttaggagacaaaccatgtgaacttgagctattaagt
gacacatccttaaccactggggatacggctgtttgcaatattaattacttagatccgaac
atcaacgtggctataccagttttctcaattcatggtaatcacgatgacccttctggtgat
ggtcgttatagtgctttggatattcttcaagtaactggcttagtgaactactttggtcgt
gttccagagaatgataacattgtggtgagtccaatattgctgcaaaaaggtttcacaaaa
cttgcattatacggaatttcaaatgttcgagatgaaagactttatcactcttttcgtgaa
aataaggttaaatttttacgtcctgatctatatcgggatgaatggttcaacttattgacc
gtacatcaaaatcactctgcccatacaccaacgagctatttacctgaaagcttcatccaa
gatttctatgacttcgtgttatggggacacgaacacgagtgtctgatagatggcagctat
aatcctacacaaaaatttacagtggtacaaccaggatcaactattgcaacttctttaagt
cctggtgaaactgcacccaagcattgtggtatcttaaatattactgggaaagattttcat
ttagagaagattcgtttgcgaacggttcggccatttataatgaaggacattattctctca
gaggtttcttccatccccccaatggtggaaaataaaaaggaagtattaacgtatttaatc
tcaaaagttgaagaggcaattactgaagcaaatgcacaatggtacgaagctcaaggaacc
gttccagtggttgaaaacgaaaagccacctcttcctttaattcggttacgtgtcgattat
acaggtggataccaaacggaaaatccccagcggttttctaatagatttgttggcagggtt
gcaaatgcaacagatgttgtccaattttatcttaaaaaaaaatacactaggtctaaaaga
aacgacggcctatatacttccgcagtagaagatatcaaaattaactctcttcgagttgag
tcattggtaaacgaatacttaaaaacaaataggctagaatgtcttcctgaagatagtctt
ggtgaagcggtggttaactttgttgaaaaagacgacagagatgctattaaagaatgcgtc
gaaacacagcttaataaacaaatcaacttattggttaaaaaacgagttacggaggaaaat
cttgaacaagaaataagctctatcatcaatgatcttccaaaaatttcaactacaaaacgg
aaagattacgaagagttaccagaggaggtatcagaaacttctataaatattgctgagcac
acacctgtacttaaacataccagctcactgttggatcatcattcaccgttagcgacttct
tcgagtgagcatgaaatggaagcaacaccttctccagcacttttgaaaaaaactaataag
cgacgagaattaccgtcttctttaacgaagaaaaataccagaacaccacaaagaagcaaa
gaagtgaaaaaagtaccagctcgtaaattgtcacaatcaacgaaaaagagtgacaaaaat
acacaatctacgcttctattttacgacccatccagcaccacagaagcgcagtacttggat
aacgaggatgacgaaattttagatgattga

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