Streptomyces poriferorum: P8A21_28805
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Entry
P8A21_28805 CDS
T10937
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
spof Streptomyces poriferorum
Pathway
spof00470
D-Amino acid metabolism
spof00550
Peptidoglycan biosynthesis
spof01100
Metabolic pathways
spof01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spof00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
P8A21_28805
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
P8A21_28805
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
P8A21_28805
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
spof01011
]
P8A21_28805
Enzymes [BR:
spof01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
P8A21_28805
Peptidoglycan biosynthesis and degradation proteins [BR:
spof01011
]
Precursor biosynthesis
Amino acid ligase
P8A21_28805
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Ortholog
Paralog
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp_4
ATP-grasp
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
WLQ51237
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All DBs
Position
6589571..6590728
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AA seq
385 aa
AA seq
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MSSENLPQSTEQQLRKPRVAVVFGGRSSEHGISVVTAGAVLNAIDRTKYDVLPIGITTDG
RWALTADEPERMAITDRKMPDVAQLAESDEGGVVLSVDPGSREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGQDKEYMKRVFTSFGLPVGPYVV
VRPREWDNDPQGARKRITDFAGEHGWPLFIKPARAGSSIGITKVDDASGLDEAIEEARRH
DPKFLVESLLRGREIECGVLEFEDGPRASVPAEIPPVTSHDFYDFEAKYIDAASGIVPAP
LTDEETAEVQRLAVEAFEAASCEGLVRADFFLTEDGGFVINEINTLPGFTPISMYPRMWQ
ESGVSYQQLVDRLIQAALDRPTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagaacctcccccagagtacggagcagcagctccgcaagccgcgtgtggcc
gtcgtgttcggcggccgcagctccgagcacggcatttcggtggtcacggccggtgcggtc
ctgaacgcgatcgaccggacgaagtacgacgtcctgccgatcggcatcacgacggacggc
cgctgggcgctcaccgccgacgaacccgaacgcatggccatcacggaccggaagatgccc
gacgtggcacaacttgccgagtccgacgagggcggcgtggtgctctccgtcgatcccggc
agccgtgaagtggtctacagcgagcccgggtcggtccccaaggcgctcggcgaggtcgac
gtcgtcttccccgtcctgcacggtccctacggtgaggacggcacgctccagggcctcctg
gagctgtccggcgtgccgtacgtcggcgcgggtgtcctcgcctcggcggtcggccaggac
aaggagtacatgaagcgcgtcttcacctccttcgggctccccgtcgggccgtacgtggtc
gtgcgcccccgcgagtgggacaacgacccccagggcgcccgcaagcgcatcacggacttc
gccggcgagcacggctggccgctcttcatcaagcccgcccgggccggctcctccatcggc
atcacgaaggtcgacgacgcctccggcctcgacgaggcgatcgaggaagcccgccgccac
gaccccaagttccttgtggagtcgctgctgcggggccgcgagatcgagtgcggggtgctg
gagttcgaggacggtccgcgcgccagcgtgcccgccgagatcccgccggtcacctcgcac
gacttctacgacttcgaggccaagtacatcgacgcggcgtccggcatcgtgcccgccccg
ctcaccgacgaggagaccgccgaggtccagcggctcgcggtcgaggccttcgaggccgcc
tcctgcgaggggctggtgcgggccgacttcttcctcaccgaggacggcggattcgtcatc
aacgagatcaacaccctgccgggcttcaccccgatctccatgtacccgcgcatgtggcag
gagagcggcgtcagctaccagcagctggtggaccggctcatccaggcggcgctggaccgg
ccgaccggcctgcgctga
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