Streptococcus pneumoniae P1031 (serotype 1): SPP_0249
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Entry
SPP_0249 CDS
T00874
Name
(GenBank) dihydrofolate:folylpolyglutamate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spp
Streptococcus pneumoniae P1031 (serotype 1)
Pathway
spp00790
Folate biosynthesis
spp01100
Metabolic pathways
spp01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SPP_0249
Enzymes [BR:
spp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SPP_0249
6.3.2.17 tetrahydrofolate synthase
SPP_0249
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ACO20718
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Position
212240..213490
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AA seq
416 aa
AA seq
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MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTGTNGKGSTIAFMRELFM
GHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKEMEKTLLQTPDQLSFFELL
TLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVITSIGLDHQETLGDSLEAIAEQ
KAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQAGQDFSVLNGDFSSSLLNLSQLN
IGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVRKALEQTHWAGRLERIRPQIYLDGA
HNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKDYQGMLGYLTENLPQVELKMTGFDYQG
SLDETDVTGYHVIPSYREFISSFEERADAQDLLFVTGSLYFISEVRGYLLDREQIN
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
atgtttgaagtagaagaatggctccatagtcggattggtttgaattttcgatcaggtttg
ggccgaatgcagcaagcggtggatttgttaggaaatcctgagcagtcttaccctattatc
cacgtaacagggactaatgggaaaggatctaccattgcttttatgagggaattatttatg
gggcatggcaaaaaagttgcgacctttacctcccctcatatcgtatccatcaatgaccga
atctgcattaatgggcaacctatagcagacgcagactttatccgtttggctgatcaggta
aaggagatggagaaaacgcttctgcaaactcctgaccagttgtccttttttgaattgctg
accttggttgcttttctttattttagggagcaggaggtggatttggttttattagaagtg
ggaattggtggcttacttgacacgaccaatgtggtaactggagagcttgctgtcatcacc
tccattgggcttgaccatcaagaaaccttgggtgatagtctagaagcaattgcagagcag
aaagctggtattttcaaggctggtaaaaaggcagtgattgcgaaattgcctccagaagct
agacttgtctgtcagaaaaaagccgaatctttagctgttgacctttatcaggcaggtcaa
gatttttcagtgctgaatggtgatttttcaagctctttactaaatctttcacagctgaac
ataggcttagaaggagcctatcagcaggagaatgcggccttggcgttgcaaacttttctt
ctttttatgggagaaagaaaggaagctattgatgaacaggctgtaagaaaggccttggaa
cagacccattgggctggtcgcttggagcgtattcgcccacagatttacttggatggtgct
cataacctccctgccttgactcgcttggttgagtttatcaaagaaaaagagcaggaaggc
tatcgacctcaaatcctctttggatccttgaaacgtaaggattatcaagggatgttgggt
tatctgactgaaaatttacctcaagtggaactcaaaatgaccggctttgactatcaaggg
tctttggacgagacagatgtaacaggttaccatgtaattccctcttaccgagaatttatc
agcagtttcgaagaaagggcagacgctcaagacttgctgttcgttacagggtctctctat
tttatctcagaagtacggggctacctgctggaccgtgagcagataaattga
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