Streptococcus pneumoniae P1031 (serotype 1): SPP_1688
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Entry
SPP_1688 CDS
T00874
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spp
Streptococcus pneumoniae P1031 (serotype 1)
Pathway
spp00300
Lysine biosynthesis
spp00550
Peptidoglycan biosynthesis
spp01100
Metabolic pathways
spp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SPP_1688
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SPP_1688
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SPP_1688
Enzymes [BR:
spp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SPP_1688
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
HBS1_N
Motif
Other DBs
NCBI-ProteinID:
ACO21194
LinkDB
All DBs
Position
complement(1562093..1563466)
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AA seq
457 aa
AA seq
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MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVPLKGALDGHDFIETAFE
NGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAH
LLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAI
VTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTPADPIVEDYLPTDKKVVRFGQGA
ELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIHQAFQ
GLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKEL
GDQSIQLHNQIILSLSPDVLDTVIFYGEDIAELAQLASQMFPIGHVYYFKKTEDQDQFED
LVKQVKESLGAHDQILLKGSNSMNLAKLVESLENEDK
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacaatctatgaagttgcccaagctgttggagctaaaaatgatgttagtctt
tttgcggacgcccagttagaaaaggctgagtttgacagtcgattgattgggactggagat
ttatttgtgccacttaaaggtgcgcttgatggccatgactttattgaaacagcctttgaa
aatggtgcagcagtaaccttgtctgagaaagaggtctcaaatcatccttacattctagta
gatgatgttttgacagcctttcaatccttagcatcctactatcttgaaaaaacgactgtt
gatgtctttgctgttacaggttcaaatggcaagacaacgactaaggatatgttggcgcat
ttactgtcaacaagatacaagacctacaaaacacaaggcaattacaataatgagattggc
cttccttacacagttcttcatatgcctgaaggaacagaaaagttggttttggagatggga
caggatcacttgggagatattcatctcttgtctgaattggctcgtccaaaaacagccatc
gtgaccttggttggagaagctcatttggcctttttcaaagatcgttctgagattgctaaa
ggaaaaatgcaaattgcagacggaatggcttcaggttccttgcttttaacgccggctgac
cctatcgtagaggactatttgccaactgataaaaaggtggtccgttttgggcaaggggca
gagttggaaatcacagacttggttgagcgtaaggacagtctgacctttaaggctaatttc
ttggaacaagcccttgatttgccagtgactggtaagtacaatgctaccaatgctatgatt
gcgtcctatgttgccctacaagaaggagtttcagaggagcaaattcatcaggccttccaa
ggtcttgaattgacgcgtaatcgtactgagtggaagaaagcagccaatggagcagatatc
ctgtcagacgtatataatgccaatccaactgctatgaagctgattttagagactttctct
gccattccagccaatgaaggtggcaagaaaattgcagtgttggcggatatgaaggagctt
ggtgaccagtctattcaactccataaccagataattttgagcctttctccagatgtgctt
gataccgttattttctatggagaagacattgctgaattagcccaacttgctagtcaaatg
ttcccaatcggacacgtttattacttcaagaaaacagaagaccaagaccaatttgaagac
ctagttaagcaggtcaaagaaagccttggggctcatgaccaaatcctgctcaaaggctct
aactctatgaatctagccaagttggtagaaagtttagaaaatgaagacaagtga
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