Streptococcus pneumoniae R6 (avirulent serotype 2): spr0162
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Entry
spr0162 CDS
T00060
Symbol
ribA
Name
(GenBank) Riboflavin biosynthesis; GTP-cyclohydrolase II
KO
K14652
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:
4.1.99.12
3.5.4.25
]
Organism
spr
Streptococcus pneumoniae R6 (avirulent serotype 2)
Pathway
spr00740
Riboflavin metabolism
spr00790
Folate biosynthesis
spr01100
Metabolic pathways
spr01110
Biosynthesis of secondary metabolites
spr01240
Biosynthesis of cofactors
Module
spr_M00125
Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD
Brite
KEGG Orthology (KO) [BR:
spr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00740 Riboflavin metabolism
spr0162 (ribA)
00790 Folate biosynthesis
spr0162 (ribA)
Enzymes [BR:
spr01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.25 GTP cyclohydrolase II
spr0162 (ribA)
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase
spr0162 (ribA)
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Paralog
GFIT
Motif
Pfam:
DHBP_synthase
GTP_cyclohydro2
PucR
Motif
Other DBs
NCBI-ProteinID:
AAK98966
UniProt:
Q8DRF1
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All DBs
Position
complement(170814..172019)
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AA seq
401 aa
AA seq
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MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTENVNFMATYAKGLICMPM
SESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEERGLTARMCVAEDITPSDF
RRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGLCCEIMNHDGKMMRTDDLIQF
SKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYGNFKAISYIDKLNGEHHLALIMG
NIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKAMKMIVENGSGVLLYLRQEGRGIGL
INKLKAYHLQDQGMDTLDANLALGFEGDLRKYHIGAQMLKDLGLQSLHLLTNNPDKVEQL
EKYGITISSRISIEIEANPYDSFYLETKKNRMGHILNMEEK
NT seq
1206 nt
NT seq
+upstream
nt +downstream
nt
atggaatatcgaaaaatacaagaagcattagaagcattgcagaagggacgacttgttctt
gttatagacgacaaggatagagaaaatgaaggagacttaatttgttctgcacaagcagct
acaacagaaaatgttaattttatggctacttatgccaaaggattaatttgtatgcctatg
agcgaaagtttagctaatcaattaatgctttcacctatggttgaaaacaatacagataat
cataagactgcttttacagtttcaattgattataaagaaacgaccacaggtatttctgcc
gaggaaagaggactgaccgcacgtatgtgtgtagctgaagatataacaccctctgatttt
cgcaggccaggacacatgtttcctttaattgcaaaaaaaggtggtgtcctagaaagaaat
ggacacacagaagcaactgttgatttattaaaattagctggactaaaagagtgtggccta
tgttgtgaaataatgaatcatgatggcaaaatgatgagaacagatgatttaattcagttc
tcgaagaaacacaacattccattaattaccatcaaagaattacaagaatatagaaaagta
tatgatcagctggtagaacgagtttcaactgtcaatatgcctactagatacggtaatttc
aaagcaattagctatatagataaactaaatggggaacatcatcttgctcttattatggga
aatatagaggatgaagccaatgtattatgtcgggtccactccgaatgtttaacaggagat
gttttaggctctttacgttgcgattgtggacagcaattcgataaagctatgaaaatgatt
gttgagaatggttcgggtgtcttactttacttgcgacaggagggacgaggaattggactt
atcaataaattaaaagcctatcatttacaagatcaaggcatggatacgcttgatgccaat
cttgcattaggctttgaaggtgatttaagaaaatatcatattggagcacaaatgcttaaa
gatctgggacttcagtcacttcatttactgacaaataatcctgacaaggttgaacagtta
gaaaaatatggaattaccatttccagtagaatatcaatcgaaatagaagccaatccttac
gatagtttttatttagaaacaaagaaaaatcgaatgggtcacattttaaatatggaggaa
aaataa
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