Streptococcus pneumoniae R6 (avirulent serotype 2): spr1219
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Entry
spr1219 CDS
T00060
Symbol
hom
Name
(GenBank) Homoserine dehydrogenase
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
spr
Streptococcus pneumoniae R6 (avirulent serotype 2)
Pathway
spr00260
Glycine, serine and threonine metabolism
spr00270
Cysteine and methionine metabolism
spr00300
Lysine biosynthesis
spr01100
Metabolic pathways
spr01110
Biosynthesis of secondary metabolites
spr01120
Microbial metabolism in diverse environments
spr01230
Biosynthesis of amino acids
Module
spr_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
spr_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
spr00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
spr1219 (hom)
00270 Cysteine and methionine metabolism
spr1219 (hom)
00300 Lysine biosynthesis
spr1219 (hom)
Enzymes [BR:
spr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
spr1219 (hom)
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Gene cluster
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Motif
Pfam:
Homoserine_dh
NAD_binding_3
ACT
GFO_IDH_MocA
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-ProteinID:
AAL00023
UniProt:
Q8DPE1
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All DBs
Position
complement(1215716..1217035)
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AA seq
439 aa
AA seq
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MAILENFEEIKMTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVKDEDEK
NRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVVTANKDLL
AVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVNGTSNFMVTK
MVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMKIAFDDVAHKGI
RNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLASVNGVMNAVFVES
IGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEYSRDLVLANPEDVKAN
YYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARVVIITHKINKAQLENVSA
ELKKVSEFDLLNTFKVLGE
NT seq
1320 nt
NT seq
+upstream
nt +downstream
nt
atggctatattagaaaatttcgaggagataaagatgacagttaaaattgctttactagga
tttggtaccgttgcaagtggtgtgcctttcctcctaaaggaaaatggaggaaaaatcaat
caatcagcacattcagatatcaaagttgctaaggtattggtcaaggatgaagatgaaaaa
aatcgcttgcttgcagcagggaatgactttaactttgtaaccaatgtggatgatatttta
tcagaccaggatattactatcgtagtggaattgatggggcgtattgagcctgctaaaacc
tttatcactcgtgccttggaagctggaaaacacgttgttactgctaacaaggacctttta
gctgtccatggcgcagaattgctagaaatcgctcaagctaacaaggtagcactttactac
gaagcagcagttgctggtgggattccaattcttcgtactttagcaaattccttggcttct
gataaaattacgcgcgtgcttggagtagtcaacggaacttccaacttcatggtgaccaag
atggtggaagaaggctggtcttacgatgatgctcttgcggaagcacaacgtctaggattt
gcagaaagcgatccgacgaatgacgtagatgggattgatgcagcctacaagatggttatt
ttgagccaatttgcctttggcatgaagattgcctttgatgatgtagcccacaagggaatc
cgcaatatcacaccagaagacgtagctgtagctcaagagcttggttacgtagtgaaattg
gttggttctattgaggaaacttcttcaggtattgctgcagaagtgactccaaccttccta
cctaaagcgcacccacttgctagtgtgaatggcgtaatgaacgctgtctttgtagaatct
atcggtattggtgagtctatgtactacggaccaggtgcgggtcaaaaaccaactgcaaca
agtgttgtagctgatattgtccgtatcgttcgtcgtttgaatgatggtactatcggcaaa
gacttcaacgaatatagccgtgacttggtcttggcaaatcctgaagatgtcaaagcaaac
tactatttctcaatcttggctctagactcaaaaggtcaggtcttgaagttggctgaaatc
ttcaatgctcaagatatttcctttaagcaaatccttcaagatggcaaagagggtgacaag
gcgcgtgtcgttatcatcacacacaagattaataaagcccagcttgaaaatgtctcagct
gaattgaagaaggtttcagaattcgacctcttgaataccttcaaggtgctaggagaataa
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