Streptomyces profundus: K4G22_06665
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Entry
K4G22_06665 CDS
T10233
Name
(GenBank) CoA-acylating methylmalonate-semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
sprf Streptomyces profundus
Pathway
sprf00280
Valine, leucine and isoleucine degradation
sprf00410
beta-Alanine metabolism
sprf00562
Inositol phosphate metabolism
sprf00640
Propanoate metabolism
sprf01100
Metabolic pathways
sprf01120
Microbial metabolism in diverse environments
sprf01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
sprf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
K4G22_06665
00562 Inositol phosphate metabolism
K4G22_06665
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
K4G22_06665
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
K4G22_06665
Enzymes [BR:
sprf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
K4G22_06665
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
K4G22_06665
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Motif
Pfam:
Aldedh
LuxC
Motif
Other DBs
NCBI-ProteinID:
UED83929
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Position
1569110..1570582
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AA seq
490 aa
AA seq
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MTKLITHWISGATRAGTSGRGAPVHDPTSGERTGETTLASADDVTAAVADSVRAASAWRG
SSLSRRAAVLFAFRELLHRHTDELASVIVAEHGKVHADAVGEVRRGLENIEFAAGVPHLL
KGDHSARAATGVDVHSVREPLGVVVGVTPFNFPAMVPLWMCGNAIAAGNAFLLKPSEKVP
SAALFLARLWQEAGLPDGVFNVLQGDGETVDALLRHPDVAAVSFVGSTPVARHVHRTGTD
QGKRVQALGGAKNHAVVLPDADVDVAADALVSAAYGSAGERCMALSVAVAVGGIGDALVR
AIGERLPEVRLGVDMGPLITREHRDRVAGYVAAGEAQGATVVADGRTAPAPAPGFFLGTT
LLDHVTPEMSVYQDEIFGPVLSVVRVDTFDEAVELVNANPYGNGTAVFTRDGGAARRFTE
EAQIGMVGVNVPLPVPIGSYSFGGWKASLFGDVHMYGPEGLSFYTRAKVVTTRWPDPATS
SVDLGFPQTR
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atgaccaagctcatcacccactggatctcgggcgcgacgcgagccggcacctcggggcgc
ggcgcgcccgtgcacgatcccacgtccggcgagcggaccggcgagaccacgctggcctcg
gccgacgatgtgacggcggcggtcgccgactccgtgcgcgccgcgtcggcctggcgcggc
agttcgctctcgcgccgcgccgccgtcctcttcgcgttccgggagctgctgcaccggcac
accgatgaactcgcctcggtcatcgtggccgagcacggcaaggtgcacgccgacgcggtg
ggcgaggtgcgccgggggcttgagaacatcgagttcgccgccggcgtgccccacctgttg
aagggcgaccactcggccagggcggcgaccggcgtcgatgtgcacagcgtgcgggagccg
ctcggggtggtcgtcggcgtcaccccgttcaacttccccgcgatggtgccgctgtggatg
tgcggcaacgcgatcgccgccggcaacgcgttcctgttgaagccgagcgagaaggtgccg
tcggccgcgctgttcctggcgcggctctggcaggaggccgggctgcccgacggcgtgttc
aacgtcctccagggcgacggggagacggtggacgcgctgctgcggcacccggatgtggcg
gcggtgagcttcgtcggctcgacgccggtggcccggcacgtccaccggacggggacggac
cagggcaagcgggtccaggcgttgggcggggcgaagaaccacgcggtggtgctgccggac
gccgatgtcgacgtggcggccgacgccctcgtgtcggccgcctacgggtcggccggcgag
cggtgcatggcgctctcggtcgcggtggcggtcggcgggatcggtgacgcgctggtgcgg
gcgatcggcgagcggctgcccgaggtgcgcctcggtgtggacatgggcccgttgatcacc
agggagcaccgggaccgggtcgccggctatgtggcggccggcgaggcgcagggcgcgacg
gtggtggccgacgggcggacggccccggcacccgcgccgggtttcttcctcggcacgacg
cttcttgaccatgtgactccggagatgagcgtctaccaggacgagatcttcggtccggtg
ctctccgtggtcagggtggacaccttcgacgaggccgtggagttggtcaacgcgaacccc
tatggcaacggcacggccgtgttcacccgggacggcggcgcggcgcggcgcttcaccgag
gaggcccagatcggcatggtgggcgtcaacgtgccgcttccggtgccgatcggctcctac
tcgttcggtggctggaaggcgtcgctcttcggcgatgtccatatgtacgggcccgagggg
ctgtcgttctacacccgcgccaaggtcgtgaccacgcgctggcccgacccggccacctcg
tccgtcgacctgggctttccgcagaccaggtga
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