Streptomyces profundus: K4G22_24245
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Entry
K4G22_24245 CDS
T10233
Symbol
ispG
Name
(GenBank) flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
sprf Streptomyces profundus
Pathway
sprf00900
Terpenoid backbone biosynthesis
sprf01100
Metabolic pathways
sprf01110
Biosynthesis of secondary metabolites
Module
sprf_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
sprf00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
K4G22_24245 (ispG)
Enzymes [BR:
sprf01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
K4G22_24245 (ispG)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
K4G22_24245 (ispG)
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Gene cluster
GFIT
Motif
Pfam:
GcpE
Zn_ribbon_9
zf-ChsH2
Motif
Other DBs
NCBI-ProteinID:
UED86926
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Position
5545785..5546939
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AA seq
384 aa
AA seq
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MTAISLGMPSVPTKLAERRVSRQIQVGSVAVGGDAPVSVQSMTTTRTSDIGSTLQQIAEL
TASGCQIVRVAVPTQDDADALATIARKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGN
IKQFDDKVKEIARVAGDAGTPIRIGVNAGSLDRRLLAKYGKATPEALVESALWECSLFEE
HGFRDIKISVKHNDPVVMVNAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSE
GIGDTIRVSLSAPPAEEIKVGAQILESLGLRERRLEIVSCPSCGRAQVDVYKLAEEVTAG
LDGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLID
EAMKIAEQMERDGVAAGEPEVAVG
NT seq
1155 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatctcgctgggaatgccgtcagtaccgaccaaactggccgaacgccgcgtc
agccgtcagatccaggtcggctccgtcgcggtagggggtgacgccccggtctccgtgcag
tcgatgaccaccacccgcacctcggacatcggttccaccctgcaacagatcgctgaactc
accgcctcgggctgccagatcgtccgggtggccgtgcccacgcaggacgacgcggacgcg
ttggcgacgatcgcgcgcaagtcgcagatccccgtgatcgccgatatccacttccagccc
aagtacgtcttcgccgccatcgatgccggctgcgccgcggtccgggtcaacccgggcaac
atcaagcagttcgacgacaaggtcaaggagatcgccagggtcgccggcgacgccggcacc
ccgatccggatcggggtcaacgccggctccctggaccggcggctgctcgccaagtacggc
aaggccacgcccgaggccctggtggagtcggcgctctgggagtgctcgctcttcgaggag
cacggcttccgggacatcaagatctccgtcaagcacaacgaccccgtggtgatggtcaac
gcctaccgtcagttggccgcgcagtgcgactacccgctgcacctgggcgtcaccgaggcg
gggcccgcgttccagggcaccatcaagtccgcggtcgccttcggcgccctgctcagcgag
ggcatcggcgacaccatccgggtctccctctccgcgccgccggccgaggagatcaaggtc
ggcgcgcagatcctggagtccctcggcctgcgcgagcgccgcctggagatcgtctcctgc
ccctcctgcgggcgggcccaggtggacgtctacaagctggccgaggaggtcaccgccggc
ctggacggcatggaggtgccgctccgcgtcgccgtcatgggctgtgtcgtcaacggtccg
ggcgaggccagggaggccgacctcggcgtcgcgtccggcaacggcaagggccagatcttc
gtcaagggcgaggtcatcaagaccgtgcccgagtccaagatcgtggagaccctgatcgac
gaggccatgaagatcgccgagcagatggagcgcgacggcgtcgccgccggcgagcccgag
gtcgccgtcggctga
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