Streptomyces profundus: K4G22_31425
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Entry
K4G22_31425 CDS
T10233
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sprf Streptomyces profundus
Pathway
sprf00280
Valine, leucine and isoleucine degradation
sprf00640
Propanoate metabolism
sprf00785
Lipoic acid metabolism
sprf01100
Metabolic pathways
sprf01110
Biosynthesis of secondary metabolites
sprf01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sprf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
K4G22_31425 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
K4G22_31425 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K4G22_31425 (pdhA)
Enzymes [BR:
sprf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
K4G22_31425 (pdhA)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
UED88159
LinkDB
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Position
complement(7633409..7634533)
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AA seq
374 aa
AA seq
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MAAETLRQQTVDRLLPSLEPVRLVAADGSAVEAPEGYVAPPDDVLCEAFRRMVVGRRFDA
QASALTRQGRLAVYPSSRGQEACQIGAALALRERDWLFPTYRDSVALVSRGLDPVEVLSL
LRGDWHCGYDPAAVRTAPQCTPLATQTIHAVGMADALRRHGAGDVVMALVGDGGTSEGDF
HEALNYAAVLRAPVVFLVQNNGYAISVPLARQTAAPALAYKGVGYGMPSEQVDGNDLVAV
LAVLSRAVERAREGRGPSLVEAHTYRMEAHTNADDPSRYRDEAEVAAWLAADPLARLETY
LRARGVLSDEDVAACEARAEELAGRLRAELATETRGDPLELFDHVFATPTPQLREQRALL
AAELAEGAEGVGER
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atggcggctgagacccttcgacaacagacggtcgatcgacttcttccctcgctcgaaccg
gtgcgtctcgtggcggccgacggctcggcggtcgaggctcccgaggggtatgtcgcgccg
ccggacgacgtgttgtgcgaggcgttccggcgcatggtcgtcggccggcggttcgacgcg
caggcgtcggcgttgacgcgccaggggcggctcgcggtgtatccgtcgagccgcgggcag
gaggcctgccagatcggggcggcgctggcgctgcgggagcgggactggctcttccccacc
taccgggactcggtggcgctggtgtcgcggggcctggacccggtggaggtgctgtcgctg
ctgcgcggcgactggcactgcggctacgatccggcggccgtgcggacggccccgcagtgc
accccgctggcgacccagacgatccacgcggtgggcatggcggacgcgctgcggcgtcat
ggcgcgggcgacgtggtgatggcgctggtgggggacggcggcaccagcgagggggacttc
cacgaggcgttgaactacgcggcggtgctgcgggcgcccgtggtgttcctggtgcagaac
aacgggtacgcgatctcggtgccgttggcgcggcagaccgcggctccggcgctggcgtac
aagggggtggggtacgggatgccgtccgagcaggtggacggcaatgacctggtcgcggtg
ttggcggtgctctcccgcgcggtggagagggcgcgggaggggcgaggcccgtccctggtg
gaggcgcacacctatcggatggaggcgcacaccaacgcggacgacccgtcgcgctatcgg
gacgaggcggaggtcgccgcgtggttggcggccgatccgctggcgcggttggagacgtat
ctgcgggcgcgcggcgtgctgtcggacgaggacgtggcggcgtgcgaggcgcgggcggag
gagctcgccggccggctgcgcgcggagttggcgacggagacgcggggggacccgttggag
ttgttcgaccatgtcttcgccaccccgacgccgcagttgcgggagcagcgtgccctgttg
gcggcggagctggccgagggagcggagggggtgggtgagcggtga
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