Streptococcus pyogenes SSI-1 (serotype M3): SPs0021
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Entry
SPs0021 CDS
T00119
Name
(GenBank) putative phosphoribosylformylglycinamidine synthase II
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
sps
Streptococcus pyogenes SSI-1 (serotype M3)
Pathway
sps00230
Purine metabolism
sps01100
Metabolic pathways
sps01110
Biosynthesis of secondary metabolites
Module
sps_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sps00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPs0021
Enzymes [BR:
sps01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SPs0021
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
GATase
Motif
Other DBs
NCBI-ProteinID:
BAC63116
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Position
30872..34597
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AA seq
1241 aa
AA seq
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MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKDLRIVQVYDVFNLAEDLLARAEKHIF
SEQVTDRLLTEAEITAELDKVAFFAIEALPGQFDQRAASSQEALLLFGSDSQVKVNTAQL
YLVNKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFSVSDKTIPNLDFFENYKADDF
AAYKADQGLAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKNIDF
SASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEINA
CSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMR
ISGAGDITTPIAETRTGKLPQQVISKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRME
LGAVVGAAHKENVVREKPEAGDVVILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQK
GNAIEERKIQRLFRDGEVTRLIKKSNDFGAGGVCVAIGELADGLEIDLDKVPLKYQGLNG
TEIAISESQERMSVVVRPNDVDAFIAACNKENIDAVVVATVTEKPNLVMTWNGETIVDLE
RRFLDTNGVRVVVDVKFVDKDLTVPEARTTSAETLEADTLKVLSDLNHASQKGLQTIFDS
SVGRSTVNHPIGGRYQITPTESSVQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYA
VIEATARLVATGADWSRARFSYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGG
KDSMSGTFEDLTVPPTLVAFGVTTADSRKVLSPEFKVAGENIYYIPGQAISEDIDFDLIK
ANFSQFEAIQAQHKITAASAAKYGGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFV
FTSAEEIADAVKIGQTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQADALEEVP
AVVSDTVIKAKETIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAES
VDTMVANIAKANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDNFIEKGGLIIGIC
NGFQALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDI
HAIPVSHGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSK
NGQIIGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atgaataaacgtatttttgttgagaaaaaggctgactttggcattaaatcggctagcctt
gtgaaagagttgacacataatctacaactgacttctttgaaggacttgcgtattgtgcag
gtctatgatgtcttcaatttggctgaggatttactggcgcgtgctgagaagcatattttc
tctgagcaggtgacagaccgtcttttgacggaagctgaaatcactgcggagcttgataag
gttgccttctttgccattgaggcgcttcctggtcaatttgaccaacgtgctgctagttcg
caagaagctttgctattatttggaagtgacagtcaggttaaggtcaatacagcccagctt
tacttggtcaataaggatattgcagaagcagagcttgaagccgttaagaactatcttttg
aaccctgttgattcgcgtttcaaggacattactttgccgcttgaagagcaggctttctct
gtatctgataagacgatccctaatcttgatttctttgaaaattataaagctgacgatttt
gcggcctataaggcagatcagggcttggctatggaggtcgatgaccttctcttcatccaa
gattatttcaaatcaatcggacgtgtgccaactgagactgagttgaaagttttggatact
tactggtcagaccactgccgtcacacaacctttgaaactgaattgaagaacattgatttt
tcagcttctaaattccaaaaacaattgcagacaacttatgataaatatatcgccatgcgt
gatgagcttggtcgttctgaaaagccacaaacacttatggatatggcgactatttttggt
cgttatgagcgtgccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcc
tgctcagttgagattgaagtagatgttgatggtgtgaaagagccttggctcctcatgttt
aagaatgagactcacaatcacccaacagaaattgagccattcggtggagcggcgacttgt
atcggtggtgctattcgtgacccattgtcagggcgttcatacgtttatcaggctatgcgt
atttcaggcgcaggcgatatcacgactccgattgcggaaacacgtactggtaaattgcca
caacaggttatttctaagactgcggcgcacggctattcttcatatggtaaccaaattgga
cttgcgacaacttatgtgcgtgagtacttccaccctggcttcgtagccaaacgcatggag
cttggagctgtggtcggagcggcacataaggaaaatgtggttcgtgaaaaaccagaagca
ggtgatgtggtaatcttgcttggtggtaaaacagggcgtgacggtgtcggcggtgcgaca
ggttcatctaaggttcaaacggttgagtctgtggaaacagctggcgcagaggtacaaaaa
gggaatgccatcgaagagcgtaagattcaacgtctcttccgtgatggtgaagtgactcgt
ctcatcaaaaaatcaaacgactttggtgctggtggtgtctgtgttgccatcggtgaattg
gctgacggtcttgaaatcgatttggacaaggtgcctcttaaataccaaggtcttaatggt
actgaaattgcaatctcagaatctcaagagcgtatgtcagtcgttgttcgtccaaatgat
gtggatgccttcatcgcagcttgcaacaaggaaaatatcgatgccgttgtagttgcgaca
gttaccgagaaaccaaatcttgtcatgacttggaatggtgaaaccatcgttgacttggaa
cgccgtttccttgataccaacggtgtccgtgtcgttgttgatgttaaattcgttgacaag
gacttgacagttccagaagcacgcacaacatcagcagagacacttgaagcagatacgctt
aaggtcttgtctgatctcaaccatgctagtcaaaaaggtcttcaaactatctttgactca
tctgttggtcgttcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgaca
gaaagttctgttcaaaaattgccagttcaacatggtgtgacaacaactgcatctgttatg
gctcaaggttacaatccttatattgcagagtggtcaccttatcacggtgctgcctatgct
gtcattgaagcgacagctcgcttggtagcaacgggtgctgactggtctcgtgcacgtttc
tcttaccaagagtactttgagcgtatggataaacaggcagagcgttttggtcagccagta
tcagctcttcttggttctattgaggctcagattcaacttggtttgccatcaatcggcggt
aaggactctatgtctggtactttcgaagacttgacagtaccaccaaccttggtagctttc
ggcgtgacaacagcggacagccgcaaggttctctctcctgagtttaaagtggctggcgaa
aacatttactatatcccaggtcaagctatttcagaagatattgattttgaccttatcaag
gctaactttagccagtttgaagctattcaagctcaacataagattacagctgcctcagcc
gctaaatacggtggtgtcctagaaagtcttgctctcatgacttttggtaaccgtatcggt
gcttctgttgaaattgcagagcttgacagcagcttgacagctcaactcggaggttttgtc
tttacatcagctgaggaaattgctgacgcggtgaaaatcggtcaaactcaggcagacttt
acagtcactgtcaatggaaatgaccttgctggcgctagccttctagcagccttcgaaggc
aaattggaagaggtttacccaacagaattcgaacaggcagacgctcttgaagaagttcct
gctgtggtatcagatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttac
attcctgtcttccctggtaccaactcagagtatgattcagctaaggcctttgaacaggtt
ggagctagtgtcaacttggtaccatttgtaaccttgaatgaggttgctattgctgagtca
gttgacactatggttgctaatattgctaaggcaaatatcatcttctttgctggaggcttc
tcagcagcggatgaaccagatgggtctgctaagtttatcgtcaatatcttgcttaacgag
aaggtccgcgcagctattgacaacttcatcgaaaaaggtggccttatcatcggtatctgt
aatggtttccaagcccttgttaaatcaggtcttcttccatacggaaacttcgaagaagct
ggtgagacaagtccaactctcttctataacgatgccaaccaacacgttgccaagatggtt
gagactcgtatcgcaaataccaactcaccttggttggcaggagttgaggtcggcgatatt
catgccatcccagtttcacacggtgaaggtaaatttgttgtcagcgcttctgaatttgca
gagctaagagacaatggtcaaatctggagccaatatgtggactttgacggacaaccatct
atggattctaaatacaatccaaacggctctgtcaatgccatcgaagggattaccagcaag
aatggtcaaatcatcggtaagatgggacactcagaacgctgggaagacggactcttccaa
aatattcctggtaacaaagaccaaaccttgtttgctagtgcagtaaaatattttacagga
aaataa
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