KEGG   Streptococcus pyogenes SSI-1 (serotype M3): SPs0025
Entry
SPs0025           CDS       T00119                                 
Name
(GenBank) putative phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
sps  Streptococcus pyogenes SSI-1 (serotype M3)
Pathway
sps00230  Purine metabolism
sps00670  One carbon pool by folate
sps01100  Metabolic pathways
sps01110  Biosynthesis of secondary metabolites
Module
sps_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:sps00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    SPs0025
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SPs0025
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sps04147]
    SPs0025
Enzymes [BR:sps01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     SPs0025
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     SPs0025
Exosome [BR:sps04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   SPs0025
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: BAC63120
UniProt: P0DD61
LinkDB
Position
38241..39788
AA seq 515 aa
MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGVETIAIDDVTGFPEMMD
GRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNLYPFKETILRPDITYDLAV
ENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAGQTTFETRQRLAAKVFRHTA
AYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENPQQDADFYQKALPIDYSIASAKQ
LNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHMNPCGIGQADDIETAWDYAYEADPV
SIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSYSEEALAILTNKKKNLRILELPFDAQA
ASEVEAEYTGVVGGLLVQNQDVVAENPSDWQVVTDRQPTEQEATALEFAWKAIKYVKSNG
IIITNDHMTLGLGAGQTNRVGSVKIAIEQAKDHLDGAVLASDAFFPFADNIEEIAAAGIK
AIIQPGGSVRDQDSIDAANKHGLTMIFTGVRHFRH
NT seq 1548 nt   +upstreamnt  +downstreamnt
atgactaaacgtgctttaatctcagtgtctgacaagtcaggaattgttgactttgcaaaa
gaattgaaaaacttgggttgggatattatctcaactggtgggactaaggttgcccttgat
aatgctggcgttgagactattgccatcgacgatgtgactggattcccagagatgatggac
ggtcgtgttaagaccctccacccaaacattcacggtgggcttttggctcgtcgcgacgct
gacagccaccttcaggctgctaaggacaacaatatcgagctgattgacctcgtggttgtc
aacctctatcccttcaaggagactatccttcgtccagacataacctatgatttggcggtg
gaaaacatcgacatcggcggtccatcaatgcttcgctcagccgctaaaaatcacgctagc
gtgaccgttgtggttgacccagcggattatgcgactgttttgggagaattggctgacgct
ggtcagacgacatttgaaacgcgtcaacgcttggcagctaaggtctttcgtcacacagca
gcctacgacgctttgattgctgagtacttcacaactcaagtgggagaggctaagcctgaa
aaattaaccatcacttacgaccttaaacaggctatgcgttacggagaaaatccacaacaa
gacgctgatttctatcaaaaagccttgccaatagactactcaatcgcttctgctaaacag
ctcaacggaaaagaattgtccttcaataatatccgtgatgccgatgcagcaatccgtatt
atccgcgatttcaaagatcgtccaactgttgttgtcctcaaacacatgaacccatgtggt
atcggacaggctgatgatattgagacagcttgggattacgcttatgaagctgacccagtt
tcaatctttggtggaattgtcgtccttaaccgtgaagttgacgcagcgacagctaagaag
atgcaccctatcttcttggaaatcatcatcgcaccatcatactcagaagaagcgctagct
attctcacaaataaaaagaaaaacttgcgaatccttgagttgccgtttgatgcccaagct
gccagcgaagtggaagctgagtacactggcgtagttggtggacttttggtgcaaaaccaa
gacgttgtggctgaaaatccatctgactggcaagtggtgacagaccgccaaccaacagaa
caagaggcgactgcccttgagtttgcctggaaggctatcaagtatgttaagtctaacggg
attattattactaacgatcacatgacgcttggactcggtgcaggtcaaaccaaccgtgtc
ggctcagtcaagattgctatcgagcaggctaaagaccaccttgacggtgccgttctagca
tcagatgccttcttcccatttgcggacaacattgaagaaatcgctgccgcagggatcaaa
gcaatcatccaaccaggtggttcagttcgtgaccaagactctattgacgccgcaaacaaa
catggcttgaccatgatcttcacaggtgtgagacattttaggcattaa

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