Streptomyces fodineus: BFF78_30735
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Entry
BFF78_30735 CDS
T05140
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spun
Streptomyces fodineus
Pathway
spun00300
Lysine biosynthesis
spun00550
Peptidoglycan biosynthesis
spun01100
Metabolic pathways
spun01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spun00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BFF78_30735
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BFF78_30735
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BFF78_30735
Enzymes [BR:
spun01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BFF78_30735
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF7916
DUF2126
Motif
Other DBs
NCBI-ProteinID:
AOR34848
UniProt:
A0A1D7YGW1
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All DBs
Position
7145375..7146781
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AA seq
468 aa
AA seq
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MIALSLAEIAAVVGGQTHDIPDPSVQVTGPVVRDSREVVPGSLFAAFVGERVDGHDFAAR
VVEAGAVAVLASRPVGVPAIVVEDVQTALGALARHVVRRLGATLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPQSLNNEIGLPLTALTATEETQFLVLEMGARGIGHIRYLTELTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPEDGAAILNADDPLVRAMASRTKAKVVLF
GESAEADVRAENVRLTDSGQPSFRLLTPSGASDVTMRLYGEHHVSNALAAAAVAHELGMS
AEEIATALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGKGRRTWA
VLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGIEASWLQLGAYNEGSWGEESVHVS
DAQAAIDLLRSELRPGDVVLVKASRSVGLESVAQALVETGAEGEVAAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagcagtcgtcggcgggcagacgcacgacata
cccgatccgtccgtccaggtcacgggcccggtcgtccgggactcccgcgaggtggtgccc
ggcagcctgttcgccgccttcgtgggcgagcgcgtggacggccacgacttcgctgcgcgg
gtcgtcgaggcgggcgcggtcgccgtactggcgtcgcgccccgtcggcgtgcccgcgatc
gtggtcgaggacgtccagacggctctcggcgccctcgcccggcacgtcgtacgccggctc
ggcgcgaccctcgtcgccctgaccggctcggcgggcaagaccagcaccaaggacctgatc
gcgcaggtgctccggcgcaaggcgccgacggtgttcacgccgcagtcgctcaacaacgag
atcgggctgccgctcaccgccctcaccgccaccgaggagacgcagttcctcgtgctggag
atgggcgcccgtggcatcgggcacatccgctacctcaccgaactgaccccgccgaggatc
ggcctggtcctcaacgtcggcaccgcccacatcggcgagttcggcggccgggagcagatc
gcccaggcgaagggggaactggtcgaggccctccccgaggacggcgcggcgatcctcaac
gccgacgacccgctggtgcgggccatggcctcccgtaccaaggcgaaggtggtccttttc
ggagagtcggccgaagcggacgtacgcgccgagaacgtgcggctcacggacagcggacag
ccttccttcagacttctcacaccctccggtgcaagcgatgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcggaagagatcgccaccgcgctctccgaggcgggctccctctcccgctggcgcatggag
gtcaccgagcgaccggacggcgtgaccatcgtcaacgacgcctacaacgccaaccccgag
tccatgcgggccgccctccgggcgctcgcggccatgggcaaggggcgccgcacgtgggcg
gtgctcggcaagatggccgagctgggggacgaggcgctcgccgagcacgacgccgtcgga
cggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcggggggattgaggcctcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcgatcgacctgttgcgcagcgagttgcgcccgggggacgtcgtgctc
gtgaaggcgtcccgttcggtgggtctggagagcgttgcccaggcgctcgtcgagaccggt
gccgagggcgaggttgccgcccgatga
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