Streptococcus pneumoniae Hungary19A 6 (serotype 19A): SPH_0152
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Entry
SPH_0152 CDS
T00658
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spv
Streptococcus pneumoniae Hungary19A 6 (serotype 19A)
Pathway
spv00230
Purine metabolism
spv01100
Metabolic pathways
spv01110
Biosynthesis of secondary metabolites
Module
spv_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPH_0152
Enzymes [BR:
spv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SPH_0152
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Paralog
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
Motif
Other DBs
NCBI-ProteinID:
ACA37152
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Position
124655..128380
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AA seq
1241 aa
AA seq
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MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDVFDLAEDLFAPAEKHIF
SEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQEALLLLGSSSDVTVNTAQL
YLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFSESDKTIPKLTFFESYTAEDF
ARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKHIDF
SASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEINA
CSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMR
ISGAGDITAPISETRAGKLPQQVISKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRME
LGAVVGAAPKGNVVREKPEAGDVIILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQK
GNAIEERKIQRLFRNGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLNKVPLKYQGLNG
TEIAISESQERMAVVVRPEDVDTFVAECNKENIDAVVVATVTEKPNLVMHWNGETIVDLE
RRFLDTNGVRVVVDAKVVDKDVKLPEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDC
SVGRSTVNHPLGGRYQLTPTEASVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYA
VIEATARLVAAGANWSKARFSYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGG
KDSMSGTFEELTVPPTLAAFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIK
KNFTQFEAIQADHKVTSASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFV
FTSPEEIAGVEKVGQTKADFTLTVNRVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVP
AVASDVVIKAKEKVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKS
VETMVDNIDKTNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGIC
NGFQALVKSGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDI
HAIPVSHGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSK
NGQIIGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggataaacgtatttttgttgaaaaaaaggctgattttcaggtcaagtcagagagtttg
gttagagagctccagcacaacttgggactgtcaagcttgaaaagtattcgtattgtgcaa
gtatatgatgtatttgacttggctgaggacttgtttgcacctgcagagaagcacattttc
tctgagcaggtaaccgaccatgttttagatgaagtatctgtgcaggcggatcttgctaac
tatgctttctttgccattgaaagtctgccagggcagtttgaccagcgtgcagcttcgtca
caggaagccttgcttttgttgggaagttcgagtgacgtgacagtcaacacagcccaactt
tacttggtgaataaagatattgatgcgactgagttggaagctgtcaaaaactacctgctc
aatccagttgattctcgtttcaaggatatcacgacagggattgccaagcaggagttttca
gagtcagacaagaccattccaaaattgactttctttgaaagctatacagcagaagacttt
gctcgctacaaggccgaacaagggatggccatggaagtggatgatttgctctttatccaa
gactactttaagtcaatcgggcgcgtgccaactgagactgaacttaaggttttggacact
tactggtctgaccactgccgtcatacgacttttgagacagagttgaaacacatcgacttt
tcagcttctaaatttcaaaagcaattgcagtcaacctatgacaagtatattgccatgcgc
gaggaattaggtcggtctgaaaaaccacaaaccttgatggatatggcgactattttcggt
cgttatgagcgtgctaatggacgattggatgatatggaagtctctgacgaaatcaatgcc
tgctcagttgaaattgaagtggacgttgatggtgtcaaggaaccttggctcctcatgttt
aaaaacgaaacccacaaccatccaacagaaattgagccatttggtggagcggctacctgt
attggtggagctattcgtgatccgttgtcaggccgttcctatgtttaccaagccatgcgt
atttcaggtgctggtgatattacagcaccgatttcggaaactcgcgctgggaaattgcca
caacaagtcatttctaaaacagcagctcatggttattcttcatatggtaaccagattggg
cttgcaacaacctacgttcgtgaatacttccacccaggctttgtagctaaacgtatggaa
cttggtgccgttgttggtgcggctcccaagggcaatgttgtccgtgaaaaacctgaagca
ggtgatgtgatcatccttctcggaggcaaaacaggtcgtgatggtgtcggtggtgcgacg
ggctcttctaaggttcaaacagttgagtctgtagagactgctggtgctgaggttcaaaaa
ggaaatgccatcgaagaacgcaagattcagcgcctcttccgtaatggcaatgtcactcgt
ctgatcaagaagtccaatgactttggggcaggcggtgtctgtgtggctatcggtgaattg
gcagacggtcttgaaatcgacctcaacaaggtgcctcttaaataccagggcttgaatggt
acagaaattgccatctctgaatcacaagaacggatggcggtcgtggttcgtcctgaagat
gtggataccttcgttgccgaatgtaacaaagaaaatattgatgctgttgtggtggcgaca
gtaactgaaaaaccaaatcttgtcatgcactggaatggtgagacaatcgttgacttggag
cgtcgtttccttgacaccaatggtgtgcgcgtggttgtcgatgccaaagttgtggacaag
gatgtcaaactcccagaagagcgtcaaacatctgctgaaacactggaatcagataccctt
acggttctatctgacctcaaccatgcaagtcaaaaaggattacagactatctttgactgc
tctgttggacgctcaacggttaatcacccacttggtggtcgttaccaactcacaccaact
gaggcatctgtgcagaaattgccagttcaacacggtgtgactcatactgcgtcggtcatt
gctcaaggtttcaacccatatgtagctgaatggtctccataccacggtgctgcttatgcg
gttatcgaagcaactgctcgtttggtggctgctggtgccaactggtccaaggctcgtttc
tcttaccaagagtatttcgagcggatggacaaacaagcagagcgtttcggtcagccagta
gccgcccttctaggttctattgaagcacaaattcagcttggcttgccatctatcggtggt
aaggactccatgtctggtacctttgaagaattgaccgttccgccaaccttggctgccttt
ggggtgacgacggcagatagccgtaaggtgctctctccagaatttaaagctgttggggaa
aatatctactacatcccaggtcaagccctctctgcagagattgattttgacttgattaag
aaaaattttactcagtttgaagccatccaagctgaccataaagtgacatctgcatcagct
gtcaaatacggtggtgtagttgaaagtttggctcttgctacctttggaaactatattggt
gcagaggtgaccttgcctgaacttaaaacagctttgacagctcaattaggcggctttgtc
ttcacatctcctgaagaaattgctggagtagagaaggttggacaaacgaaagcagacttt
acactgactgtcaaccgtgtgaaactagatggacacaagcttgacagtgcatttcaaggg
acattggaagaagtttacccaacagaatttacccaagcgaaagaactagaagaagtacca
gctgtggcatcagatgttgtgattaaagccaaagaaaaggttgaaaaacctgtggtttac
atcccagtctttccaggaaccaactcagaatatgattcagctaaggccttcgaaaaagaa
ggtgcagaggtcaatttggtgccattcgtgaccttgaatgaagaagctattgtcaagtca
gttgaaactatggttgacaatatcgacaagactaatattctcttctttgctggtggattc
tcggctgcggatgaaccagatggttcagctaagtttatcgtcaatatcctgcttaatgaa
aaagtgcgtgtggctattgatagctttatcgcccgtggtggcttgattatcggtatttgt
aatggattccaagccttagtcaaatcgggtctcctaccatacggaaactttgaagatgct
aacagtactagtccaaccctcttctacaatgatgccaaccaacacgtggccaagatggtg
gaaactcgtattgccaataccaactcaccatggttggctggtgtgcaagtgggcgatatc
cacgctattcctgtttcgcacggtgaagggaagtttgtcgtgacggctgaggaatttgca
gagctccgtgacaatggacaaattttcagccaatacgttgactttaacggtaaaccaagt
atggattctaagtacaatccgaatggttctgtccatgccatcgaaggaattaccagcaag
aatggtcaaatcatcggtaagatgggccactcagaacgttatgaggatggtcttttccaa
aatatcccaggcaataaagaccagcacctgttcgcgtcagcggttaaacatttcactgga
aaataa
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