KEGG   Streptococcus pneumoniae Hungary19A 6 (serotype 19A): SPH_0468
Entry
SPH_0468          CDS       T00658                                 
Symbol
rfbB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
spv  Streptococcus pneumoniae Hungary19A 6 (serotype 19A)
Pathway
spv00521  Streptomycin biosynthesis
spv00523  Polyketide sugar unit biosynthesis
spv00525  Acarbose and validamycin biosynthesis
spv00541  Biosynthesis of various nucleotide sugars
spv01100  Metabolic pathways
spv01110  Biosynthesis of secondary metabolites
spv01250  Biosynthesis of nucleotide sugars
Module
spv_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:spv00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    SPH_0468 (rfbB)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    SPH_0468 (rfbB)
   01055 Biosynthesis of vancomycin group antibiotics
    SPH_0468 (rfbB)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    SPH_0468 (rfbB)
   00525 Acarbose and validamycin biosynthesis
    SPH_0468 (rfbB)
Enzymes [BR:spv01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     SPH_0468 (rfbB)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase NAD_binding_4 3Beta_HSD Polysacc_synt_2 RmlD_sub_bind NAD_binding_10 NmrA adh_short Sacchrp_dh_NADP KR
Other DBs
NCBI-ProteinID: ACA35950
UniProt: B1I977
LinkDB
Position
417883..418932
AA seq 349 aa
MTEYKKIIVTGGAGFIGSNFVHYVYNNFTDVHVTVLDRLTYAGNRANIEEILGDRVELVV
GDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDLRF
HHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFG
VKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLYGEGKNVRDWIHTNDHSSGVWTI
LTKGQIGETYLIGADGEKNNKEVLELILKEMGQATDAYDHVTDRAGHDLRYAIDASKLRE
ELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKEAVEANYAKTQEIITV
NT seq 1050 nt   +upstreamnt  +downstreamnt
atgactgaatacaaaaaaattatcgtgacaggtggagctggttttatcggttctaacttt
gttcactatgtttacaataactttacagatgtccatgtgacagtgctggacaggctgact
tatgcaggtaatcgtgccaatattgaagaaattttaggcgaccgtgttgagttagtcgtt
ggagatattgctgatgcagccttggtagataagttagcagctgaagcggatgccattgta
cactatgcggcagaaagccacaatgacaattcgcttaatgacccctcgccatttatccat
accaacttcatcggaacttatacactcttggaagcggctcgtaaatacgaccttcgtttc
caccatgtgtcgactgacgaagtctatggggatctgccgctgcgtgaagatttaccaggt
catggggaaggaccaggtgagaaatttacggctgaaaccaagtacaatccaagctcgcct
tactcatcgactaaggcggcttcagatttgattgtcaaagcctgggtgcgttcttttgga
gtcaaggcaacgatttccaactgttcaaataactacggtccttatcaacatatcgaaaaa
ttcatcccacgtcagattactaacatcctaagtggaattaagccaaaactttacggtgaa
ggtaagaatgttcgtgactggattcataccaatgaccattcttcaggagtttggacaatc
ttgacaaaagggcaaatcggtgaaacctacttgattggggctgatggtgagaagaacaat
aaggaagttttggaacttatccttaaggaaatgggacaagctacggatgcctatgatcat
gtgactgaccgtgcaggacatgaccttcgctatgcgattgatgccagcaagctccgtgag
gagttggggtggaaacctgaatttaccaactttgaagctgggctcaaggcaacaatcaag
tggtatacagataaccaagaatggtggaaagcagaaaaagaagctgttgaagccaattat
gctaagactcaggagattattacagtataa

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