Streptococcus pneumoniae Hungary19A 6 (serotype 19A): SPH_0684
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Entry
SPH_0684 CDS
T00658
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
spv
Streptococcus pneumoniae Hungary19A 6 (serotype 19A)
Pathway
spv00270
Cysteine and methionine metabolism
spv00450
Selenocompound metabolism
spv01100
Metabolic pathways
spv01110
Biosynthesis of secondary metabolites
spv01230
Biosynthesis of amino acids
Module
spv_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
spv00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SPH_0684 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SPH_0684 (metE)
Enzymes [BR:
spv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
SPH_0684 (metE)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
ACA36765
UniProt:
B1IAA7
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Position
628633..630882
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AA seq
749 aa
AA seq
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MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAKHWNIVKEKGITEIPSN
DFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQGEKGDVRALPMKKWFNTNY
HYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVGPFTFLQLSDFEEGVKADDFV
DSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAEEKALFLNLYNKLLADKKGLEVLLQ
TYFGDVRDVYADLVNLPVDAIGFDFVEGKKTLELVKGGFPADKTLYAGIVNGKNIWRNNY
EKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEEFEPALLNHFAFAVEKLDEIRDLDAIR
NGQGSEALAANKELFATERVGENAELRARIAGLTDTDYTRLPAFAEREAIQEEAFKLPAL
PTTTIGSFPQTKEVRAKRLAYRKGELSQKEYDAFLAETIDEWIKWQEDIDFDVLVHGEFE
RNDMVEYFGQNLSGYLFSKNGWVQSYGMRGVKPPIIWGDVTRLNPITVKWSSYAQSRTNK
PVKGMLTGPVTILNWSFPREDISIKDSTLQIALAIKDEVLDLEAAGVKIIQIDEAALREK
LPLRRSDWYEDYLDWAIPAFRLVHSTVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFE
ASRSNLEILDELKAKNFQTEVGPGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPD
CGLKTRGIPETKESLIRLVEAAKAAREKL
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgtcaactacaatcgtcggtttccctcgtttgggcgaattccgtgaattaaaatttaca
actgaaaaatactttagaaaagaaatctcagaagaagaacttttagcagcagcaaaagac
ttgcgtgctaaacactggaacattgtcaaagaaaaaggcatcactgaaattccatcaaat
gacttttctcactatgataacttcctagatgcggctttccttttcaacgtggtgcctgca
tccgttcaaaacttggacttgtctgaccttgagcgctacttcgctttgggacgtggttac
cagggagaaaaaggggacgttcgcgccctcccaatgaagaaatggtttaacactaactac
cactacatcgttcctaaatttgaaaaagacactcaagtaaaattggctggtcacaagatt
tttgatgagttccaagaagccaaagaacttggattgaacactcgtcctgttcttgtaggt
cccttcactttccttcaattgtcagactttgaagaaggcgtgaaagcagacgacttcgta
gatagcttagtggctgcttaccaagaagtttttgctaaattggctgaacttggtgcgact
tgcatccaattggatgaagcggctcttgtaaaagacttgacagctgaagaaaaagctctc
ttcttgaacctttacaacaaactcttggctgacaaaaaaggtcttgaagtcttgcttcaa
acttatttcggtgatgttcgtgacgtatacgctgaccttgtaaacttgccagtagatgct
atcggttttgactttgttgaaggtaagaaaactcttgaactcgttaaaggtggcttccca
gctgacaagactctctatgcaggtattgtcaatggtaaaaacatctggcgcaacaactat
gaaaagagcttggctgttcttgagcaaatcccagctgaaaacatcgttttgacaagctct
tgctcacttcttcatgtgccatttacaactgctaatgaagaatttgaaccagcactcttg
aaccactttgcctttgcagttgaaaaattggatgaaatccgtgacttggatgctatccgc
aatggtcaaggttcagaagctcttgcagccaacaaagaactctttgcgactgagcgtgtt
ggtgaaaatgctgaacttcgtgcgcgtatcgctggcttgacagacacagactacactcgt
ttgccagcctttgcagaacgtgaagctatccaagaagaagctttcaaacttccagctctt
ccaacaacaacgattggttcattccctcaaacaaaagaagttcgtgccaaacgtttggct
taccgtaaaggtgaattgtctcaaaaagagtacgatgctttccttgctgaaacgattgac
gaatggatcaagtggcaagaagatattgactttgatgtccttgttcacggtgaatttgag
cgtaatgacatggttgagtacttcggtcaaaacttgtcaggatacctcttctctaaaaat
ggatgggtacaatcatacggtatgcgtggggtaaaaccaccaatcatctggggtgatgtc
actcgtcttaaccctatcactgttaaatggtctagctatgcacaaagtcgtacaaacaaa
cctgttaaaggtatgttgactggacctgttaccatccttaactggtcattcccacgtgaa
gacatctctatcaaggattcaactctccaaatcgcccttgctatcaaggatgaagtactt
gaccttgaagctgctggtgtgaaaatcatccaaatcgacgaggctgctcttcgtgaaaaa
ttgccactccgccgtagcgactggtacgaagactaccttgactgggctattcctgccttc
cgcttggtacactcaacagtagcgccagacacacaaatccacactcacatgtgttactca
gaatttacagatatcatcccagctatcgataacatggatgcagacgttatttcctttgaa
gctagccgttcaaaccttgaaatcttggacgaactcaaagcgaaaaacttccaaacagaa
gtgggacctggggtttacgatatccactcacctcgtgtaccaaatgaaggcgaaatcgac
aacacaatcgaagccatccttgctaaagtgccaagcaagaaagtttggatcaaccctgac
tgtggtttgaaaacacgtggtatcccagaaacaaaagaaagcttgatccgccttgttgaa
gcagctaaagctgcgcgtgagaaattgtaa
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