Streptococcus pneumoniae CGSP14 (serotype 14): SPCG_0047
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Entry
SPCG_0047 CDS
T00690
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase, putative
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spw
Streptococcus pneumoniae CGSP14 (serotype 14)
Pathway
spw00230
Purine metabolism
spw01100
Metabolic pathways
spw01110
Biosynthesis of secondary metabolites
Module
spw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPCG_0047 (purL)
Enzymes [BR:
spw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SPCG_0047 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
ACB89299
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Position
46909..50637
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AA seq
1242 aa
AA seq
DB search
MMDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDVFDLAEDLFAPAEKHI
FSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQEALLLLGSSSDVTVNTAQ
LYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFSESDKTIPKLTFFESYTAED
FARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKHID
FSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEIN
ACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAM
RISGAGDITAPISETRAGKLPQQVISKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRM
ELGAVVGAAPKGNVVREKPEAGDVIILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQ
KGNAIEERKIQRLFRNGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLNKVPLKYQGLN
GTEIAISESQERMAVVVRPEDVDTFVAECNKENIDAVVVATVTEKPNLVMHWNGETIVDL
ERRFLDTNGVRVVVDAKVVDKDVKLPEERQTSAETLESDTLTVLSDLNHASQKGLQTIFD
CSVGRSTVNHPLGGRYQLTPTEASVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAY
AVIEATARLVAAGANWSKARFSYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIG
GKDSMSGTFEELTVPPTLVAFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLI
KKNFAQFEASQADHKVTSASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGF
VFTSPEEIAGVEKIGQTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEV
PAVASDVVIKAKEKVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVK
SVETMVDNIDKTNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGI
CNGFQALVKSGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGD
IHAIPVSHGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITS
KNGQIIGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK
NT seq
3729 nt
NT seq
+upstream
nt +downstream
nt
ttgatggataaacgtatttttgttgaaaaaaaggctgattttcaggtcaagtcagagagt
ttggttagagagctccagcacaacttgggactgtcaagcttgaaaagtattcgtattgtg
caagtatatgatgtatttgacttggctgaggacttgtttgcacctgcagagaagcacatt
ttctctgagcagggaaccgaccatgttttagatgaagtatctgtgcaggcggatcttgct
aactatgctttctttgccattgaaagtctgccagggcagtttgaccagcgtgcagcttcg
tcacaggaagccttgcttttgttgggaagttcgagtgacgtgacagtcaacacagcccaa
ctttacttggtgaataaagatattgatgcgactgagttggaagctgtcaaaaactacctg
ctcaatccagttgattctcgtttcaaggatatcacgacagggattgccaagcaggagttt
tcagagtcagacaagaccattccaaaattgactttctttgaaagctatacagcagaagac
tttgctcgctacaaggccgagcaagggatggccatggaagtggatgatttgctctttatc
caagactactttaagtcaatcgggcgcgtgccaactgagactgaactcaaggttttggac
acttactggtctgaccactgccgtcatacgacttttgagacagagttgaaacacatcgac
ttttcagcttctaaatttcaaaagcaattgcagtcaacctatgacaagtatattgccatg
cgcgaggagttaggtcggtctgaaaaaccacaaaccttgatggatatggcgactattttc
ggtcgttatgagcgtgctaacggacgattggatgatatggaagtctctgacgaaatcaat
gcctgctcagttgaaattgaagtggatgttgatggtgtcaaggaaccttggctcctcatg
tttaaaaatgaaacccacaaccatccaacagaaattgagccatttggtggagcggctacc
tgtatcggtggagctattcgtgatccgttgtcaggccgttcctatgtttaccaagccatg
cgtatttcaggtgctggtgatattacagcaccgatttcggaaactcgtgctgggaaattg
ccacaacaagtcatttctaaaacagcagctcatggttattcttcatatggtaaccagatt
gggcttgccacaacctacgttcgtgaatacttccacccaggctttgtagctaaacgtatg
gaacttggtgccgttgttggtgcggctcccaagggcaatgttgtccgtgaaaaacctgaa
gcaggtgatgtgatcatccttctcggaggcaaaacaggtcgtgatggtgtcggtggtgcg
acgggctcttctaaggttcaaacagttgagtctgtagagactgctggtgctgaggttcaa
aaaggaaatgccatcgaagaacgcaagattcagcgcctcttccgtaatggcaatgtcact
cgtctgatcaagaagtccaatgactttggggcaggcggcgtctgtgtggctatcggtgaa
ttggcagacggtcttgaaatcgacctcaacaaggtgcctcttaaataccagggcttgaat
ggtacagaaattgccatctctgaatcacaagaacggatggcggtcgtggttcgtcctgaa
gatgtggataccttcgttgccgaatgtaacaaagaaaatattgatgctgttgtggtggcg
acagtaactgaaaaaccaaatcttgtcatgcactggaatggtgagacaatcgttgacttg
gagcgtcgtttccttgacaccaatggtgtgcgcgtggttgtcgatgccaaagttgtggac
aaggatgtcaaactcccagaagagcgtcaaacatctgctgaaacactggaatcagatacc
cttacggttctatctgacctcaaccatgcaagtcaaaaaggattacagactatctttgac
tgctctgttggacgctcaacggttaatcacccacttggtggtcgttaccaactcacacca
actgaggcatctgtgcagaaattgccagttcaacacggtgtgactcatactgcgtcggtc
attgctcaaggtttcaacccatatgtagctgaatggtctccataccacggtgctgcttat
gcggttatcgaagcaactgctcgtttggtggctgctggtgccaactggtctaaggctcgt
ttctcttaccaagaatatttcgagcggatggacaagcaagcagagcgtttcggtcagcca
gtagctgctcttctaggttctattgaagcacaaattcagcttggcttgccatctatcggt
ggtaaggactccatgtctggtacctttgaagaattgaccgttccgccaaccttggttgcc
tttggggtgacgacggcagatagccgtaaggtgctctctccagaatttaaagctgttggg
gaaaatatctactacatcccaggtcaagccctctctgcagagattgattttgacttgatt
aagaaaaattttgctcagtttgaagcaagccaagctgaccataaagtgacgtctgcatca
gctgtcaaatacggtggtgtagttgaaagtttggctcttgctacctttggaaactatatt
ggtgcagaggtgaccttgcctgaacttaaaacagctttgacagctcaattaggcggcttt
gtcttcacatctcctgaagaaattgctggagtagagaagattggacaaacgaaagcagac
tttacactgactgtcaacggtgtgaagctagatggacacaagcttgacagtgcatttcaa
gggacattggaagaagtttacccaacagaatttacccaagcgaaagaactagaagaagta
ccagctgtggcatcagatgttgtgattaaagccaaagaaaaggttgaaaaacctgtggtt
tacatcccagtctttccaggaaccaactcagaatatgattcagctaaggccttcgaaaaa
gaaggtgcagaggtcaatttggtgccattcgtgaccttgaatgaagaagctattgtcaag
tcagttgaaactatggttgacaatatcgacaagactaatattctcttctttgccggtgga
ttctcggctgcggatgaaccagatggttcagctaagtttatcgtcaatatcctgcttaat
gaaaaagtgcgtgtggctattgatagctttatcgcccgtggtggcttgattatcggtatt
tgtaatggattccaagccttagtcaaatcgggtctcctaccatacggaaactttgaagat
gctaacagtactagtccaaccctcttctacaatgatgccaaccaacacgtggccaagatg
gtggaaactcgcattgccaataccaactcaccatggttggctggtgtgcaagtgggcgat
atccacgctattcctgtttcgcacggtgaagggaagtttgtcgtgacggctgaggaattt
gcagagctccgtgacaatggacaaattttcagccaatacgttgactttaacggtaaacca
agtatggattctaagtacaatccgaatggttctgtccatgccatcgaaggaattaccagc
aagaatggtcaaatcatcggtaagatgggccactcagaacgttatgaggatggtcttttc
caaaatatcccaggcaataaagaccaacacctgttcgcatcagcggttaaacatttcact
ggaaaataa
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