Streptococcus pneumoniae CGSP14 (serotype 14): SPCG_0052
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Entry
SPCG_0052 CDS
T00690
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
spw
Streptococcus pneumoniae CGSP14 (serotype 14)
Pathway
spw00230
Purine metabolism
spw00670
One carbon pool by folate
spw01100
Metabolic pathways
spw01110
Biosynthesis of secondary metabolites
Module
spw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPCG_0052 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SPCG_0052 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
spw04147
]
SPCG_0052 (purH)
Enzymes [BR:
spw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
SPCG_0052 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
SPCG_0052 (purH)
Exosome [BR:
spw04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
SPCG_0052 (purH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
ACB89304
LinkDB
All DBs
Position
54370..55938
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AA seq
522 aa
AA seq
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MIKKENIMTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGVDTIAIDDVT
GFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNLYPFKETILKPD
VTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAANGETSYETRQRLAA
KVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENPQQDADFYQKALPTDY
SIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHMNPCGIGQADDIETAWDY
AYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSYTDEALAILINKKKNLRILA
LPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQVVTKRQPTETEATALEFAWKAI
KYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQAKDRLDGAVLASDAFFPFADNVEE
IAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFTGVRHFRH
NT seq
1569 nt
NT seq
+upstream
nt +downstream
nt
atgattaaaaaggagaatataatgactaaacgcgtcttaatcagcgtctcagacaaagcg
ggcattgttgaatttgcccaagaactcaaaaaacttggttgggagattatctcaacaggt
ggaactaaggttgcccttgataatgctggggtggataccattgctatcgatgatgtgact
ggtttcccagaaatgatggacggtcgtgtgaagaccctccacccaaatatccacggaggg
cttctcgctcgtcgtgacttggatagccacttggaagcggctaaggacaacaagattgag
ctcattgaccttgtggtggtcaacctttacccatttaaggaaactatccttaaaccagat
gtgacttatgctgatgcagttgaaaatatcgatattggtgggccatctatgcttcgttca
gcagcgaaaaatcatgccagtgttacagttgtggtagatcctgctgactacgctgtggtt
ttggacgaattggcagcaaacggcgaaacctcttatgaaactcgccaacgtttagcagcc
aaagtatttcgtcacacagcggcttatgacgccttgattgcagaatacttcacagctcaa
gtgggtgaaagcaagcctgaaaaactcactttgacttatgacctcaagcaaccaatgcgt
tacggtgagaatcctcaacaagacgcggacttttaccagaaagctttgcctacagattac
tctattgcttcagccaaacagctcaacgggaaagaattgtcatttaataatatccgtgat
gcagatgctgctatccgtatcatccgtgacttcaaagatagtccaaccgttgtggctctc
aaacacatgaatccatgtggaattggtcaagctgatgacatcgagactgcttgggactac
gcttatgagtctgatccagtatctatctttggtgggattgtcgtcctcaaccgtgaggtg
gatgctgcgacagctgagaagatgcacggcgttttcctcgaaatcatcattgcaccaagc
tatacggatgaagcgctagctattttgatcaataaaaagaaaaacttgcgtatccttgcc
ttgccatttaatgctcaagaggctagcgaagtggaagcagaatacacaggtgtagtcggt
ggacttctcgtgcaaaatcaagacgtggtcaaggaaagcccagctgactggcaagtggtg
accaaacgtcagccaaccgagacagaagcgactgctcttgagttcgcttggaaggctatc
aagtacgtcaaatcaaatggtattatcgtgaccaacgaccacatgacacttggtgttggt
ccaggtcaaaccaaccgtgtggcttctgttcgccttgccattgaccaagccaaagatcgt
ctggacggggcggtccttgcttcagatgccttcttcccatttgcggataacgtggaagaa
atcgccaaagcaggaattaaggccatcatccagcccggtggctctgtccgtgaccaagaa
tctatcgaagcggcagacaaatatggcttgaccatggtctttacaggcgtgagacatttt
agacattaa
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