Streptococcus pneumoniae CGSP14 (serotype 14): SPCG_0551
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Entry
SPCG_0551 CDS
T00690
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
spw
Streptococcus pneumoniae CGSP14 (serotype 14)
Pathway
spw00270
Cysteine and methionine metabolism
spw00450
Selenocompound metabolism
spw01100
Metabolic pathways
spw01110
Biosynthesis of secondary metabolites
spw01230
Biosynthesis of amino acids
Module
spw_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
spw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SPCG_0551 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SPCG_0551 (metE)
Enzymes [BR:
spw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
SPCG_0551 (metE)
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Paralog
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
ACB89803
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Position
543958..546387
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AA seq
809 aa
AA seq
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MEYSCKVRITKDLRRLLQVFFFCPKQIYSFKLYQTLIFYNYTDAFFSVKIVSTTNFGGHI
MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAKHWNIVKEKGITEIPSN
DFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQGEKGDVRALPMKKWFNTNY
HYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVGPFTFLQLSDFEEGVKADDFV
DSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEKALFLNLYNKLLADKKGLEVLLQ
TYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVKGGFPADKTLYVGIVNGKNIWRNNY
EKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEEFEPALLNHFAFAVEKLDEIRDLDAIR
NGQGSEALAANKELFATERVGENAELRARIADLTDADYTRLPAFAEREAIQEEAFKLPAL
PTTTIGSFPQTKEVRAKRLAYRKGELSQKEYDAFLAETIDEWIKWQEDIDFDVLVHGEFE
RNDMVEYFGQNLSGYLFSKNGWVQSYGMRGVKPPIIWGDVTRLNPITVKWSSYAQSRTNK
PVKGMLTGPVTILNWSFPREDISIKDSTLQIALAIKDEVLDLEVAGVKIIQIDEAALREK
LPLRRSDWYEDYLDWAIPAFRLVHSTVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFE
ASRSNLEILDELKAKNFQTEVGPGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPD
CGLKTRGIPETKESLIRLVEAAKAAREKL
NT seq
2430 nt
NT seq
+upstream
nt +downstream
nt
ttggaatatagctgtaaagtaagaattacaaaggatttgagacgtttgcttcaagtcttt
ttcttttgtccgaaacagatatatagtttcaaactatatcaaaccctaattttttacaat
tatacagacgctttcttttctgttaagatagtttcaacaacaaattttggaggacacatc
atgtcaactacaatcatcggtttccctcgtttgggcgaattccgtgaattaaaatttaca
actgaaaaatactttagaaaagaaatctcagaagaagaacttttagcagcagcaaaagac
ttgcgtgctaaacactggaacattgtcaaagaaaaaggcatcactgaaattccatcaaat
gacttttctcactatgataacttcctagatgcggctttccttttcaacgtggtgcctgca
tccgttcaaaacttggacttgtctgaccttgagcgctacttcgctttgggacgtggttac
cagggagaaaaaggggacgttcgcgcccttccaatgaagaaatggttcaacactaactac
cactacatcgttcctaaatttgaaaaagacactcaagtgaaattggctggtcacaagatt
ttcgatgagttccaagaagcaaaagaacttggattgaacactcgtccagttcttgtaggt
cccttcactttccttcaattgtcagactttgaagaaggcgtgaaagcagacgacttcgta
gatagcttagtggctgcttaccaagaagtttttgctaaattggctgaacttggtgcgact
cgcatccaattggatgaagcggctcttgtaaaagacttgacagctgaagaaaaagctctc
ttcttgaacctttacaacaaactcttggctgacaaaaaaggtcttgaagtcttgcttcaa
acttatttcggtgatgttcgtgacgtatacgctgaccttgtaaacttgccagtagatgct
atcggtcttgactttgttgaaggtaagaaaactcttgaactcgttaaaggtggcttccca
gctgacaagactctctatgtaggtattgtcaatggtaaaaacatctggcgcaacaactac
gaaaagagcttggctgttcttgagcaaatcccagctgaaaacatcgttttgacaagctct
tgctcacttcttcatgtgccatttacaactgctaatgaagaatttgaaccagcactcttg
aaccactttgcctttgcagttgaaaaattggatgaaatccgtgacttggatgctatccgc
aatggtcaaggttcagaagctcttgcagccaacaaagaactctttgcgactgagcgtgtt
ggtgaaaatgctgaacttcgtgcgcgtatcgctgacttgacagacgcagactacactcgt
ttgccagcctttgcagaacgtgaagctatccaagaagaagctttcaaacttccagctctt
ccaacaacaacgattggttcattccctcaaacaaaagaagttcgtgccaaacgtttggct
taccgtaaaggtgaattgtctcaaaaagagtacgatgctttccttgctgaaacgattgac
gaatggatcaagtggcaagaagatattgactttgatgtccttgttcacggtgaatttgag
cgtaatgacatggttgagtacttcggtcaaaacttgtcaggatacctcttctctaaaaat
ggatgggtacaatcatacggtatgcgtggggtaaaaccaccaatcatctggggtgatgtc
actcgtcttaaccctatcactgttaaatggtctagctatgcacaaagtcgtacaaacaaa
cctgttaaaggtatgttgactggacctgttaccatccttaactggtcattcccacgtgaa
gacatctctatcaaggattcaactcttcaaatcgcccttgctatcaaggatgaagtactt
gaccttgaagttgctggtgtgaagatcatccaaatcgatgaggctgctcttcgtgaaaaa
ttgccactccgtcgtagcgactggtacgaagactaccttgactgggcaattcctgccttc
cgcttggtacactcaacagtagcgccagacacacaaatccacactcacatgtgttactca
gaatttacagatatcatcccagctatcgataacatggatgcagacgttatttcctttgaa
gctagccgttcaaaccttgaaatcttggacgaactcaaagcgaaaaacttccaaacagaa
gtgggacctggggtttacgatatccactcacctcgtgtaccaaatgaaggcgaaatcgac
aacacaatcgaagccatccttgctaaagtgccaagcaagaaagtttggatcaaccctgac
tgtggtttgaaaacacgtggtatcccagaaacaaaagaaagcttgatccgccttgttgaa
gcagctaaagctgcgcgtgagaaattgtaa
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