Streptococcus pyogenes M1 GAS (serotype M1): SPy_0167
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Entry
SPy_0167 CDS
T00050
Symbol
slo
Name
(GenBank) streptolysin O precursor
KO
K11031
thiol-activated cytolysin
Organism
spy
Streptococcus pyogenes M1 GAS (serotype M1)
Pathway
spy02024
Quorum sensing
Brite
KEGG Orthology (KO) [BR:
spy00001
]
09140 Cellular Processes
09145 Cellular community - prokaryotes
02024 Quorum sensing
SPy_0167 (slo)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02042 Bacterial toxins [BR:
spy02042
]
SPy_0167 (slo)
Bacterial toxins [BR:
spy02042
]
Type II toxins: Membrane damaging toxins
Pore-forming toxins, Beta-pore-forming/Cholesterol-dependent
SPy_0167 (slo)
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Gene cluster
GFIT
Motif
Pfam:
Thiol_cytolysin
Thiol_cytolys_C
DUF6479
New_glue
Motif
Other DBs
NCBI-ProteinID:
AAK33267
UniProt:
P0C0I3
Structure
PDB
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Position
151443..153158
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AA seq
571 aa
AA seq
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MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTTE
KAGQKTDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNE
LEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAALQL
ANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWHDNY
SGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQI
FYTVSANLPNNPADVFDKSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSND
VEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIKDNA
TFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHQGAYVAQYEIL
WDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRK
VIDERDVKLSKEINVNISGSTLSPYGSITYK
NT seq
1716 nt
NT seq
+upstream
nt +downstream
nt
atgtctaataaaaaaacatttaaaaaatacagtcgcgtcgctgggctactgacggcagct
cttatcattggtaaccttgttactgctaatgctgaatcgaacaaacaaaacactgctagt
acagaaaccacaacgacaaatgagcaaccaaagccagaaagtagtgagctaactactgaa
aaagcaggtcagaaaacggatgatatgcttaactctaacgatatgattaagcttgctccc
aaagaaatgccactagaatctgcagaaaaagaagaaaaaaagtcagaagacaaaaaaaag
agcgaagaagatcacactgaagaaatcaatgacaagatttattcactaaattataatgag
cttgaagtacttgctaaaaatggtgaaaccattgaaaattttgttcctaaagaaggcgtt
aagaaagctgataaatttattgtcattgaaagaaagaaaaaaaatatcaacactacacca
gtcgatatttccattattgactctgtcactgataggacctatccagcagcccttcagctg
gctaataaaggttttaccgaaaacaaaccagacgcggtagtcaccaagcgaaacccacaa
aaaatccatattgatttaccaggtatgggagacaaagcaacggttgaggtcaatgaccct
acctatgccaatgtttcaacagctattgataatcttgttaaccaatggcatgataattat
tctggtggtaatacgcttcctgccagaacacaatatactgaatcaatggtatattctaag
tcacagattgaagcagctctaaatgttaatagcaaaatcttagatggtactttaggcatt
gatttcaagtcgatttcaaaaggtgaaaagaaggtgatgattgcagcatacaagcaaatt
ttttacaccgtatcagcaaaccttcctaataatcctgcggatgtgtttgataaatcggtg
acctttaaagagttgcaacgaaaaggtgtcagcaatgaagctccgccactctttgtgagt
aacgtagcctatggtcgaactgtttttgtcaaactagaaacaagttctaaaagtaatgat
gttgaagcggcctttagtgcagctctaaaaggaacagatgttaaaactaatggaaaatat
tctgatatcttagaaaatagctcatttacagctgtcgttttaggaggagatgctgcagag
cacaataaggtagtcacaaaagactttgatgttattagaaacgttatcaaagacaatgct
accttcagtagaaaaaacccagcttatcctatttcatacaccagtgttttccttaaaaat
aataaaattgcgggtgtcaataacagaactgaatacgttgaaacaacatctaccgagtac
actagtggaaaaattaacctgtctcatcaaggcgcgtatgttgctcaatatgaaatcctt
tgggatgaaatcaattatgatgacaaaggaaaagaagtgattacaaaacgacgttgggac
aacaactggtatagtaagacatcaccatttagcacagttatcccactaggagctaattca
cgaaatatccgtatcatggctagagagtgcactggcttagcttgggaatggtggcgaaaa
gtgatcgacgaaagagatgtgaaactgtctaaagaaatcaatgtcaatatctcaggatca
accttgagcccatatggttcgattacttataagtag
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