KEGG   Streptococcus pyogenes M1 GAS (serotype M1): SPy_0185
Entry
SPy_0185          CDS       T00050                                 
Symbol
polA
Name
(GenBank) DNA-directed DNA polymerase I
  KO
K02335  DNA polymerase I [EC:2.7.7.7]
Organism
spy  Streptococcus pyogenes M1 GAS (serotype M1)
Pathway
spy03030  DNA replication
spy03410  Base excision repair
spy03420  Nucleotide excision repair
spy03440  Homologous recombination
Brite
KEGG Orthology (KO) [BR:spy00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    SPy_0185 (polA)
   03410 Base excision repair
    SPy_0185 (polA)
   03420 Nucleotide excision repair
    SPy_0185 (polA)
   03440 Homologous recombination
    SPy_0185 (polA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:spy03032]
    SPy_0185 (polA)
   03400 DNA repair and recombination proteins [BR:spy03400]
    SPy_0185 (polA)
Enzymes [BR:spy01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     SPy_0185 (polA)
DNA replication proteins [BR:spy03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     SPy_0185 (polA)
DNA repair and recombination proteins [BR:spy03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA polymerase I
     SPy_0185 (polA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     SPy_0185 (polA)
SSDB
Motif
Pfam: DNA_pol_A 5_3_exonuc_N 5_3_exonuc DNA_polI_exo1 WHD_BrxR
Other DBs
NCBI-ProteinID: AAK33285
UniProt: Q9A1M8
LinkDB
Position
171523..174165
AA seq 880 aa
MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV
LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII
GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN
DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLGLLAT
DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
FEKMQLPLEMTKKTKTGYSTAVNVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDRAADVTANDRRNAKAVNFGIVYGI
SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGHSWYEAK
NT seq 2643 nt   +upstreamnt  +downstreamnt
atggaaaacaagaataaattactattaattgatgggtcatctgttgcctttcgtgccttt
tttgccctctacaatcaaattgaccgctttaaaaaccatagcggtcttcataccaatgcc
atttatggctttcatttgatgctagaccacatgatgaagcgagtccagcccacacacgtg
ctggtggcttttgatgcgggcaaaaccaccttccggacagaaatgtatgccgattataag
gcgggtcgcgctaaaaccccagaggaatttcgtgagcagtttccttatattcgtgagatg
ttgacagcccttgggattgcttattatgagttggaacactacgaagcagacgatattatc
gggacgcttgataaaatggcggagcgcacagaagtgccttttgatgtgaccattgtcagt
ggtgataaagatttgatccagttaactgacgaaaataccgtggttgaaatttctaaaaaa
ggggtagccgaatttgaagaattcacaccggcttacctcatggaaaaaatgggattgacg
ccaaaccagtttattgacctcaaagccttgatgggagataaatcggataatattccagga
gtgaccaaaatcggtgaaaaaactgggctcaagctccttcatgaatttggtagtttagaa
ggtatctacgagcatattgatggattcaagacctcaaaaatgaaagaaaacttgattaat
gatcgtgaccaagctttcctatctaaaacgctcgccactatcaatacagcatctcctatc
acaattggcttagatgatattgtctacaatggtccagatgttgctagtctctctcaattt
tacgatgagatggattttgtgcaactcaagaaaggtcttgctagccagatgcctcaagag
ccagtagctgtcatttcctatcaagaagtgaccaatgtgtctgctgatttgtttagcgca
gaagacatcttctactttgaaacgcttcgggacaattaccatcgtgaggccatcattggt
tttgcttggggacatggtgagcagatttacgcatccacagaccttggcctattagcgacg
gatagttttaagcaggtcttccaaaaacccattgccacttatgattttaaacgtagcaag
gtcttgttgagccacttaggaattgagttggtagcacctagctatgatgctagattagct
aattaccttctgtcaactgtagaagacaatgagcttagcaccattgcccgcatttttact
gacatctctttggaagaagacgatacagtctatggtaaaggtgctaaacgggctgttcct
gataaagacgtcttactagaacacttagctcgtaaggtcaaagtattattagatagcaag
tctcaaatgctagacaagctcactgcccatgagcaactagacctctatcagaatattgaa
ttgcctttggctaatgtccttgctaaaatggaaattgaagggatcaaggttaatagggcg
actttgcaagatatggcagagcaaaacaaggtcattattgaagcgctcacccaagagatt
tatgatatggctggccaagaatttaatatcaattcgcctaaacagttaggcagtatcttg
tttgagaagatgcaactacctcttgagatgactaagaagaccaaaacaggttattctaca
gctgttaatgttttggaacgtttggcaccgattgctccaattgtggctaaaattttggat
taccgccagattaccaaattacagtctacttatgtgattggtttacaggattatattctg
gctgatggcaagattcatacccgctatgtgcaggatctcacgcagacagggcgtttgtct
agtgtggaccctaatcttcaaaacattcccattcgtttggaacaggggcgtttgattcgt
aaggcctttaccccatctcatgaagatgccgtcttgttgagttcagattactcacagatt
gaattgcgggtactggcacatatttcaggggatgagcatttgattgctgcctttaatgaa
ggggcagacattcatacctcaacggctatgcgtgtgtttgggattgacagggcagcagat
gttactgccaatgaccgccgtaatgccaaggctgttaactttggaattgtgtatgggatt
tctgattttggtttgtcaaataaccttggtatcacccgtaaacaggccaagtcttacatt
gatacctattttgaacgctatcctgggattaaagcctatatggaaaatgtggtgcgtgag
gctaaagacaagggctatgtagagaccctctttaagcgtcgtcgtgaattaccggatatc
aactctcgtaatttcaacgttcgctcttttgcggagcgtacagccatcaactcgcccatt
caaggaagcgcagctgatattctcaaaatcgctatgattaatctggataaggccttgcaa
gcaggtggttttagagctaaaatgctgcttcaagtgcatgatgaaatcgttttggaagtg
ccaaatgatgagttgactgctataaaaaaacttgtcaaagacaccatggaagctgctgtt
gatttagctgttcctttatgtgtcgatgaaagtactgggcatagctggtacgaagccaaa
taa

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