Streptococcus pyogenes M1 GAS (serotype M1): SPy_0814
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Entry
SPy_0814 CDS
T00050
Symbol
folC.2
Name
(GenBank) putative folyl-polyglutamate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spy
Streptococcus pyogenes M1 GAS (serotype M1)
Pathway
spy00790
Folate biosynthesis
spy01100
Metabolic pathways
spy01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spy00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SPy_0814 (folC.2)
Enzymes [BR:
spy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SPy_0814 (folC.2)
6.3.2.17 tetrahydrofolate synthase
SPy_0814 (folC.2)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AAK33750
UniProt:
Q9A0E1
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Position
complement(670499..671767)
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AA seq
422 aa
AA seq
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MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHVVGTNGKGSVTAYLQHI
LSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVIRPILTKMSLETNWDRPTE
FELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHALAVVCPSISFDHQERLGYSLA
EIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGSRLYQLGKDFLLNPSEKTFSFQH
DNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFPKISPKTIQKGIEATTWPGRSEFIQ
PNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILFAGLKRKPLADLLAQLDTFEVSVTTFD
FPEANLLEDYPDKYPQVKDYRDWLQGSVTSDELFVVTGSLYFISEVRQYCLSNANIFKNI
FP
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgactacctatgatagcatttcctggattcatacctttaaggctaatggtcgcaagacc
gatttggccagaatggcttggttacttgaggcactaggccggccacaagacaaattccct
gctattcacgttgttggaactaacggcaagggctctgtgacagcctacttacagcatatc
ctgtcaacttctggttatcaggtcggaacctttacatctccttttattatctcttttcac
gatcggatttgccttaatggccagcccatttcagacctagaattggcgcaatgtgtgagc
gtgattagacccattctcactaaaatgtctcttgaaacaaattgggatagacctaccgag
tttgagttagtgacgctcataatgttttgctactttgccaatcttaaacctgttgatatt
gccattattgaggcagggattggtgggaaaaccgacgcaaccaatgtttttcatgctctg
gccgtcgtatgcccttctattagttttgatcaccaagaacgtttaggttatagcctagca
gaaattgctcaccaaaaagcagaagttatcaaagctaaagaacccgttattatcggtcaa
cttgagcaggaggctagtcaagtctttcaacaagttacccaaaaagccggttcacgctta
tatcaattaggaaaagattttttgctcaatccttcagaaaagacgttttcctttcaacac
gataacttgaatttaaccaaactccgtctcaaactattaggtcaacatcaaaaagcgaat
gcctgtttagccattatgacagctcaattacttagaaaatcctttcctaaaatatctcca
aaaacgattcaaaaaggaattgaggcaacaacttggcctggccggtccgaatttattcaa
cctaatcttctattagacggcgctcacaatccagattccattgctaaattaaagtctcta
ctgcaagaagaatttcccaaacgtcctattcatattctctttgcaggtctcaaacgtaag
cctttagccgacttgctggctcaactagatacttttgaagtatctgtcacgacttttgat
ttccctgaagcaaatcttttagaggattatcctgataaatacccacaggtaaaagattac
agagactggttacaaggttccgtaacatctgatgaactctttgttgttacagggtcactt
tattttatctccgaggtaaggcaatattgtctgagcaacgcaaatatctttaaaaacata
ttcccctaa
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