Streptococcus pyogenes M1 GAS (serotype M1): SPy_1164
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Entry
SPy_1164 CDS
T00050
Symbol
topA
Name
(GenBank) putative DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
spy
Streptococcus pyogenes M1 GAS (serotype M1)
Brite
KEGG Orthology (KO) [BR:
spy00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
spy03032
]
SPy_1164 (topA)
03400 DNA repair and recombination proteins [BR:
spy03400
]
SPy_1164 (topA)
Enzymes [BR:
spy01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
SPy_1164 (topA)
DNA replication proteins [BR:
spy03032
]
Prokaryotic type
DNA Topoisomerases
SPy_1164 (topA)
DNA repair and recombination proteins [BR:
spy03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
SPy_1164 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_Top1
Toprim
C1_2
DUF2996
Toprim_4
HypA
Motif
Other DBs
NCBI-ProteinID:
AAK34035
UniProt:
Q99ZM4
LinkDB
All DBs
Position
956719..958848
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AA seq
709 aa
AA seq
DB search
MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDL
KKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYLASDPDREGEAISWHLSHI
LGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQARRVLDRIVGYSISPILWKK
VKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDGLFKKGTKKFQATFYGINGKKTK
LDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMV
AQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQNDAAQFIINRFGANYSKHGNRVKNTS
GVQDAHEAIRPSSVNHTPDSIAKYLNKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQN
GVIFVANGSQMKFDGYMAVYNDSDKNKMLPEMAEGETVKKISTSPEQHFTQPPARYSEAT
LIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVDVA
FTAEMEGKLDQVEIGEEQWQHVIDQFYQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGH
PMVIKLGRFGKFYACSNFPECRNTKAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQY
PDCEFISWDLPIGRACPKSGDYLIEKKVRGGKQVMCSNETCDYKEEKIK
NT seq
2130 nt
NT seq
+upstream
nt +downstream
nt
ttgggaacaaaaactacaactaagccaaaaacgggtactaaaaagtccaccactaaaaag
aaatcaacagcgaaaaaaaatctcgttattgttgaatcacctgccaaagctaagactatt
gaaaaatatcttggacgcagttataaagttgttgcttcggtaggacatattcgtgactta
aaaaaatcgtctatgtctattgattttgataataattatgagccacaatacattaatatc
cgtggtaagggaccccttatcaattctttaaaaaaagaagccaaagctgctaaaaaagtt
tatttagctagtgacccggatcgtgagggagaggctatttcttggcatttgtcacatatc
ttaggacttgatcctcaagataataaccgagtggtttttaatgaaattacgaaagatgca
gttaaacatgcctttgtggagcctcgtcagattgatatggacttggtagattctcaacaa
gcacgtcgtgttttggaccgtattgtgggatattccatttcaccaattctttggaaaaag
gtcaaaaaaggactttcagcaggacgtgtccagtcggttgctttaaaactcatcattgac
cgtgaaaatgacatcaaagcatttgttccaaaggaatactggtctattgatggtcttttt
aaaaaaggaactaaaaagtttcaagcgactttttacggtattaatggcaaaaaaacaaag
cttgacaataacaacgatgtcaaagaggtattagcaaagctaacaaatgaagattttctt
gtcagcaaggttgacaagaaagagcgacgtcgtaatgctcccttaccttacacaacatca
tctcttcaacaagatgctgctaataaaatcaatttcagaacgcgtaaaaccatgatggta
gcccaacaactgtatgaggggattcatttaggagaaaatggaactcaaggtttaattacc
tatatgcgtacggattctactcgtatcagtccagtagcacaaaacgatgctgctcaattt
attatcaatcgctttggagctaattattcaaaacatggtaatcgtgtcaaaaataccagt
ggtgtccaagatgctcacgaggcgattcgtccatctagtgttaatcatacgccagactct
attgccaaataccttaacaaggatcagttaaaactttatacgcttatttggaatcgtttt
gtggctagccaaatgacagcagctgtttttgataccgtaaaggtgaacttggagcaaaat
ggcgtgatttttgttgccaatggtagccaaatgaagtttgatggttacatggctgtttac
aatgattccgataaaaacaaaatgttacctgagatggcagaaggagaaacggttaaaaaa
atatcgacctctccagaacagcactttacgcagccaccagctcgttattctgaagcaact
ctaattaaaacgctagaagaaaatggtgttggacgtccatcaacttacgctccaacctta
gaagtcattcaacgcagatactatgttaaattgtctgctaagcgctttgagccaactgag
cttggggaaattgtcaacaagcttattgtcgaatttttcccagatattgtcgatgttgcc
tttactgccgagatggaaggtaagctagatcaagttgaaatcggagaagaacaatggcaa
catgttatcgatcaattctatcaaccctttgtcaaagaattgaataaggctgagtctgaa
attgaaaagattcaaatcaaagatgaaccagctggcttcgactgtgatgtttgtggtcac
ccaatggtcattaagttaggacgttttgggaaattttacgcgtgtagcaacttcccagag
tgccgtaatacaaaagccatcactaaagaaattggtgttacttgtccggtttgtcataaa
ggacaagttatcgagcgtaaaaccaaaaaaaataggatattttatggttgtgatcagtat
ccagattgtgagtttatctcgtgggatttacctattggacgtgcttgccctaagtcaggt
gactatcttattgagaaaaaagttcgtggtggcaaacaagtaatgtgtagcaatgagacc
tgtgattacaaggaagaaaaaattaaataa
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