Streptococcus pyogenes M1 GAS (serotype M1): SPy_2085
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Entry
SPy_2085 CDS
T00050
Symbol
fhs.2
Name
(GenBank) putative formate-tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spy
Streptococcus pyogenes M1 GAS (serotype M1)
Pathway
spy00670
One carbon pool by folate
spy00720
Other carbon fixation pathways
spy01100
Metabolic pathways
spy01120
Microbial metabolism in diverse environments
spy01200
Carbon metabolism
spy01240
Biosynthesis of cofactors
Module
spy_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spy00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
SPy_2085 (fhs.2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SPy_2085 (fhs.2)
Enzymes [BR:
spy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
SPy_2085 (fhs.2)
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
Motif
Other DBs
NCBI-ProteinID:
AAK34738
UniProt:
Q99XR2
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All DBs
Position
1736465..1738138
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AA seq
557 aa
AA seq
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MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDARQLVALKNKPDGKLILV
TAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPM
EDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVD
GLQGKVNGIPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLK
AGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPN
LDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGGRE
LAEKVVTLAEQDNQFRFVYEEDDSIETKLTKIVTKVYGGKGINLSSAAKRELADLERLGF
GNYPICMAKTQYSFSDDAKKLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVP
ASETIDIDEEGNITGLF
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atggttttatcagatattgaaatagccaactctgtcactatggaacctatcagtaaggtt
gccgatcaattagggattgacaaggaggcgctctgtctctatggtaagtacaaggcaaaa
attgatgcccgtcaactggtcgccttaaaaaacaaacctgatggcaaactcattcttgtc
actgctatctcaccaacaccagctggtgaaggcaaaaccaccacttctgttggattggta
gatgctctttctgccattggaaaaaaagcagttattgcccttcgtgaaccttctcttggt
cctgtttttggggttaagggaggagctgctggcggtggccacgcgcaagttgtcccaatg
gaagacatcaaccttcactttacaggggactttcatgccatcggtgtcgccaacaactta
ttagctgccttgattgataaccacattcaccatggcaatagcctaggcattgattccaga
cgtatcacttggaaacgtgtggtggatatgaatgaccgccagcttcgtcatattgttgac
ggcttgcaaggcaaggtcaacgggattcctcgtgaagatggttatgacattaccgtcgcc
tctgaaatcatggcaatcctgtgcctatccgaaaatatttctgacctcaaagcccgcctt
gaaaaaatcatcatcggttacaactaccaaggtgaacctgtaacagctaaagacttgaaa
gctggtggtgccctagccgctctgctcaaggatgcgattcatcctaatctcgtgcaaacc
ctggaacacacaccagccctcattcacggtggcccatttgctaatatcgcccatggctgt
aatagtgtcctcgccaccaaactagccttgaaatatggtgattatgccgttaccgaagct
ggatttggcgctgaccttggagctgaaaaattcattgacatcaaatgccgcatgtcaggc
cttcgcccagcagccgttgtcctagtagccactatacgtgcccttaaaatgcatgggggt
gtgccaaaagcagacctggctactgaaaatgttcaggccgttgtggatggtttacctaac
cttgacaaacatttggctaatatccaagacgtctatggccttccagttgtcgtggcgatc
aataaattcccgcttgataccgatgccgaattacaagctgtctatgatgcctgcgacaaa
cgtggcgttgacgttgtgatttctgatgtttgggcaaatggcggagctggtggccgtgaa
ctggctgaaaaagtcgtgacactagccgagcaagacaatcaattccgctttgtttatgag
gaagacgatagcattgaaaccaaactgactaaaatcgttaccaaagtttacggtggtaaa
ggcatcaacttgagctcagcagccaaacgtgaactggctgacttagaacgcctcggcttt
ggcaactacccaatttgcatggccaaaacccaatattccttctcagacgatgccaaaaaa
cttggcgcaccaactgactttacagtgactattagcaaccttaaagtgtccgcaggagca
ggatttatcgttgccctaacaggtgctatcatgaccatgcctggccttccaaaagtacct
gccagcgaaacaattgatattgacgaggagggcaacatcacaggactattctaa
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