Streptococcus pyogenes A20 (serotype M1): A20_0060
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Entry
A20_0060 CDS
T02335
Symbol
purH
Name
(GenBank) phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
spya
Streptococcus pyogenes A20 (serotype M1)
Pathway
spya00230
Purine metabolism
spya00670
One carbon pool by folate
spya01100
Metabolic pathways
spya01110
Biosynthesis of secondary metabolites
Module
spya_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spya00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
A20_0060 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
A20_0060 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
spya04147
]
A20_0060 (purH)
Enzymes [BR:
spya01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
A20_0060 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
A20_0060 (purH)
Exosome [BR:
spya04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
A20_0060 (purH)
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
AFV37169
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All DBs
Position
44106..45653
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AA seq
515 aa
AA seq
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MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVTLDDAGVETIAIDDVTRFPEMMD
GRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNLYPFKETILRPDITYDLAV
ENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAGQTTFETRQRLAAKVFRHTA
AYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENPQQDADFYQKALPTDYSIASAKQ
LNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHMNPCGIGQADDIETAWDYTYKADPV
SIFGGIIVLNREVDAATAKKMHPIFLEIIIAPSYSEEALAILTNKKKNLRILELPFDAQA
ASEVEAEYTGVVGGLLVQNQDVVAENPSDWQVVTDRQPTEQEATALEFAWKAIKYVKSNG
IIITNDHMTLGLGAGQTNRVGSVKIAIEQAKDHLDGAVLASDAFFPFADNIEEIAAAGIK
AIIQPGGSVRDQDSIDAANKHGLTMIFTGVRHFRH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgactaaacgtgctttaatctcagtgtctgacaagtcaggaattgttgactttgcaaaa
gaattgaaaaacttgggttgggatattatctcaactggtgggactaaggttacccttgac
gatgctggtgttgagaccattgccatcgacgatgtgactagattcccagagatgatggac
ggtcgtgttaagaccctccacccaaacattcacggtgggcttttggctcgtcgcgacgct
gacagccaccttcaggctgctaaggacaacaatatcgagctgattgacctcgtggttgtc
aacctctatcccttcaaggagactatccttcgtccagacataacctatgatttggcggtg
gaaaacatcgacatcggcggtccatcaatgcttcgctcagccgctaaaaatcacgctagc
gtgaccgttgtggttgacccagcggattatgcgactgttttgggagaattggctgacgct
ggtcagacgacatttgaaacgcgtcaacgcttggcagctaaggtctttcgtcacacagca
gcctacgacgctttgattgctgagtacttcacaactcaagtgggagaggctaagcctgaa
aaattaaccatcacttacgaccttaaacaggctatgcgttacggagaaaatccacaacaa
gacgctgatttctatcaaaaagccttgccaacagactactcaattgcttctgctaaacag
ctcaacggaaaagaattgtctttcaataatatccgtgatgccgatgcggcaatccgtatt
atccgcgatttcaaagaccgtccaactgttgttgctctcaaacacatgaacccatgtggt
atcggacaggctgatgacattgagactgcttgggattacacttataaagctgacccagtt
tcaatctttggcggaattattgtccttaaccgtgaagttgacgcagcgacagccaagaag
atgcaccctatcttcttggaaatcatcatcgcaccatcatactcagaagaagcgctagct
attctcacaaataaaaagaaaaacttgcgaatccttgagttgccgtttgatgcccaagct
gccagcgaagtggaagctgagtacactggcgtagttggtggacttttggtgcaaaaccaa
gacgttgtggctgaaaatccatctgactggcaagtggtgacagaccgccaaccaacagaa
caagaggcgactgcccttgagtttgcctggaaggctatcaagtatgttaagtctaacggg
attattattactaacgatcacatgacgcttggactcggtgcaggtcaaaccaaccgtgtc
ggctcagtcaagattgctatcgagcaggctaaagaccaccttgacggtgccgttctagca
tcagatgccttcttcccatttgcggacaacattgaagaaatcgctgccgcagggatcaaa
gcaatcatccaaccaggtggttcagttcgtgaccaagactctattgacgccgcaaacaaa
catggcttgaccatgatcttcacaggtgtgagacattttaggcattaa
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