Streptococcus pyogenes A20 (serotype M1): A20_1191c
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Entry
A20_1191c CDS
T02335
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spya
Streptococcus pyogenes A20 (serotype M1)
Pathway
spya00550
Peptidoglycan biosynthesis
spya01100
Metabolic pathways
spya01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spya00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A20_1191c (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A20_1191c (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A20_1191c (murF)
Enzymes [BR:
spya01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A20_1191c (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MurT_C
DUF4419
Motif
Other DBs
NCBI-ProteinID:
AFV38273
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Position
complement(1133441..1134832)
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AA seq
463 aa
AA seq
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MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLPLKGQRDGHEFIDLAFQ
NGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDVIAVTGSNGKTSTKDMIGA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHMGDIRLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAPGDPIIDPYLPENQMVIRFGNQQ
EIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVTDEDIIAALQ
TVTLTGNRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKKIAVLADMKEL
GKDSVILHSQLIDSLTSGNIDQLVFYGDHIKELARLASQVYPAEQVHYFLKTEQEDQFEA
MAQYVQNILNPFDQILLKGSHSMSLEKLVDRLVTDKNCDSYQP
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaaccttacacgaagtggctaaaatagttgacgcccaaaataatgtgtctgac
ttagacgacgttcctctgcatcacattgaatttgatagccgaaagattacaaaaggagac
ctctttttacccttaaaaggtcaaagggatggtcatgagtttattgatttagcctttcaa
aatggagctgtcgctactttttcagaaaaagaattgccggggaaacctcaccttcttgtt
gaagactgcctaaaagcttttcaaaagctagcccattattatattgataagatgcgcgtg
gatgttattgctgtgacaggctcaaatggtaaaacttccaccaaagatatgataggagct
gtcctatcaaccacttacaaaacttacaaaacgcaaggaaattacaataatgagattggt
ttgccttacaccgttctccacatgcctgacgatacggaaaaaattgttcttgaaatggga
caagatcacatgggagatattcgtcttctgtctgaaattgcaaggcctcgtattgcagtt
ttaaccttagtcggcgaagctcatttagaatattttggaagccgagacaaaatagcccaa
ggcaaaatgcagattgttgacggcatgaattcagatgggattttaattgctccgggagat
ccgattattgacccatatcttccagaaaatcagatggttatccgttttggaaatcagcag
gaaattgacgttactggtattcaagaagacaaagatagcttaacgtttacaacaaatgtg
ttagcaacacctgtgtccctacctctaccaggaaaatacaacgcgaccaatgctatggta
gcagcctatgtaggaaaactattggcagtaacagacgaggatattatagctgctttacag
actgtgacgttgacaggtaatcgtacggagtggaaaaaagcagccaatggtgctgatatt
ttgtcagatgtctacaatgccaacccaacagccatgcgtctgattttagaaacatttgct
aacatagcaaagaaccccggaggaaaaaagattgcagtgctagcagatatgaaagaactt
ggaaaggattcagtgatacttcattctcagttaattgacagcttaacatcaggtaatatt
gatcagcttgttttttatggggatcatattaaagaattagcacggttggcaagtcaggtt
tatcctgctgagcaagtacattattttttaaaaactgaacaagaagaccagtttgaagcc
atggcacaatatgttcaaaacattcttaatccctttgatcaaattcttttaaaaggcagc
cactcgatgtcgctagaaaagttagtagatcgattagtgactgacaagaattgtgacagc
tatcagccttga
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