Streptococcus pyogenes M1 476 (serotype M1): M1GAS476_0817
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Entry
M1GAS476_0817 CDS
T02499
Symbol
acoC
Name
(GenBank) branched-chain alpha-keto acid dehydrogenase subunit E2
KO
K00627
pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:
2.3.1.12
]
Organism
spym
Streptococcus pyogenes M1 476 (serotype M1)
Pathway
spym00010
Glycolysis / Gluconeogenesis
spym00020
Citrate cycle (TCA cycle)
spym00620
Pyruvate metabolism
spym00785
Lipoic acid metabolism
spym01100
Metabolic pathways
spym01110
Biosynthesis of secondary metabolites
spym01120
Microbial metabolism in diverse environments
spym01200
Carbon metabolism
spym01210
2-Oxocarboxylic acid metabolism
Module
spym_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spym00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
M1GAS476_0817 (acoC)
00020 Citrate cycle (TCA cycle)
M1GAS476_0817 (acoC)
00620 Pyruvate metabolism
M1GAS476_0817 (acoC)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M1GAS476_0817 (acoC)
Enzymes [BR:
spym01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.12 dihydrolipoyllysine-residue acetyltransferase
M1GAS476_0817 (acoC)
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Gene cluster
GFIT
Motif
Pfam:
2-oxoacid_dh
E3_binding
Biotin_lipoyl
Biotin_lipoyl_2
PYNP_C
PLA2_B
Motif
Other DBs
NCBI-ProteinID:
BAM30147
UniProt:
J7M9Z5
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All DBs
Position
1:774134..775543
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AA seq
469 aa
AA seq
DB search
MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKTNMELEAEDSGVLLKIT
RQAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASADAGPAVAPKENVASPAPQV
AATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKGRVHKEDVENFKGAQPKASPL
ARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKPAEAKAPAAKEEKVVDLPEGVEH
KPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMIALRKKLIDPIMAKTGLKVSFTDLI
GMAVVKTLMKPEHEYMNASLINDANDIELHRFVNLGIAVGLDDGLIVPVIHGANKMCLSD
FVLASKDVIKKAQTGKLKAAEMSGSTFSITNLGMFGTKTFNPIINQPNSAILGVGATIPT
PTVVDGEIVSRPIMAMCLTIDHRLVDGMNGAKFMVDLKKLMENPFELLI
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atggcatttgaaattattatgccaaagctgggcgttgacatgcaagaaggcgagatcatc
gagtggaaaaaacaagaaggtgataccgtcaatgaaggtgatatccttcttgaaatcatg
tcagacaaaaccaatatggaacttgaggcagaagactcaggtgttcttcttaaaattaca
cgtcaagcaggtgatactgtacctgtaactgaagttatcggttacattggtgcagagggt
gaatcagtagatactattgcttcaagtgaaaaaacaacagaaattccagttcctgcttca
gcagacgctggaccagcagttgctccaaaagaaaatgtggcaagtccagctcctcaagtg
gcagcgacagctattccgcaaggaaatggcggaaaagttcgtgctactccagctgcacgt
aaggcagcagcagaaatgggcattgaccttggccaagttccaggaacaggaccaaaagga
cgtgtccataaagaagacgttgaaaactttaaaggtgctcaaccgaaagcttcaccactt
gctcgtaaaattgcagcagacaaaggtattgatttggcaaccgtatcaggtactggcttt
aacggtaaggtcatgaaagaagacatcatggctattcttgaagcggctaaaccagctgaa
gcaaaagccccagcagctaaagaagaaaaagttgttgatcttccagaaggtgtggaacac
aagccaatgtcagctatgcgtaaggcaatctctaaaggtatgacaaactcttaccttact
gcccctacctttacgcttaactacgatattgacatgacagagatgattgcccttcgtaag
aagttaattgacccaatcatggctaaaacaggccttaaagtcagctttacagacttgatt
ggtatggcagtggttaaaaccttgatgaaacctgagcatgagtacatgaatgcttccctc
atcaatgatgctaatgatattgaattgcaccgctttgtgaaccttggtattgccgtaggt
cttgatgatggtcttatcgttcctgttatccatggggctaacaagatgtgcttgtcagat
ttcgtgcttgcttcaaaagatgtgattaaaaaagcgcaaactggtaagttgaaagcagct
gaaatgtctggatcaaccttctctatcacaaacttgggaatgtttggtacgaagacattt
aacccaattattaaccaaccaaactcagcaattcttggtgttggagcaactatcccaact
ccaacggttgtggatggtgagattgtttcccgtccaattatggcaatgtgcctaaccatc
gaccaccgtttagttgatggtatgaacggtgcaaaattcatggttgatctcaagaaattg
atggaaaatccatttgaattgttaatctga
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