Streptococcus pyogenes M1 476 (serotype M1): M1GAS476_1801
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Entry
M1GAS476_1801 CDS
T02499
Symbol
pbp2A
Name
(GenBank) multimodular transpeptidase-transglycosylase
KO
K12555
penicillin-binding protein 2A [EC:
2.4.99.28
3.4.16.4
]
Organism
spym
Streptococcus pyogenes M1 476 (serotype M1)
Pathway
spym00550
Peptidoglycan biosynthesis
spym01100
Metabolic pathways
spym01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
spym00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
M1GAS476_1801 (pbp2A)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
M1GAS476_1801 (pbp2A)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
spym01003
]
M1GAS476_1801 (pbp2A)
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
spym01011
]
M1GAS476_1801 (pbp2A)
Enzymes [BR:
spym01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.99 Transferring other glycosyl groups
2.4.99.28 peptidoglycan glycosyltransferase
M1GAS476_1801 (pbp2A)
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
M1GAS476_1801 (pbp2A)
Glycosyltransferases [BR:
spym01003
]
Polysaccharide
Bacterial polysaccharide (excluding LPS)
M1GAS476_1801 (pbp2A)
Peptidoglycan biosynthesis and degradation proteins [BR:
spym01011
]
Peptidoglycan biosynthesis and degradation
Glycosyltransferase/DD-Transpeptidase (Class A PBP)
M1GAS476_1801 (pbp2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transgly
Transpeptidase
YrhK
Motif
Other DBs
NCBI-ProteinID:
BAM31111
LinkDB
All DBs
Position
1:complement(1705846..1708182)
Genome browser
AA seq
778 aa
AA seq
DB search
MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANHLDSSATKNSEQDPATA
LQRSRAYEGSPKSRPAWLQKLEAVLPSPQRPIRRFWRRYHIGKLLMILIGTLVLLLGSYL
FYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSYVELNAISDDLENAVIATEDR
TFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTK
KYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTAANLTLDEAATLAGMLKGPEIYNPY
HSLKNATHRRDTVLGAMVDAKKITQTKAQQARAVGLKNRLADTYVGKTDDYKYPSYFDAV
ISEAIATYGLSEKDIVNNGYKVYTELDQNYQTGMQTTFNNDELFPVSAYDGSSAQAASVA
LDPKTGGVRGLIGRVNSSENPTFRSFNYATQAKRSPASTIKPLVVYAPAVASGWSIEKEL
PNTVQDFDGYQPHNYGNYESEDVPMYQALANSYNIPAVSTLNDIGIDKAFTYGKTFGLDM
SSAKKELGVALGGSVTTNPLEMAQAYAAFANNGVIHPAHLINRIENARGEVLKTFTDKAK
RVVSQSVADKMTAMMLGTFSNGTAVNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTP
DVVISQWVGFNQTDENHYLTDSSAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISA
VYGVNETGNQSGVDTQSIIDGLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR
NT seq
2337 nt
NT seq
+upstream
nt +downstream
nt
atgagatttctagaacttttacaaaagaaattttttcctaaagcatatcaggaaaaacaa
ttcttaatgcatcaaaaaacgcgtttaacgccacaacacaatcaaaagcagtattcgcca
aatgccaatcatttggactcatcagctaccaaaaactcagaacaagaccctgcaacagct
ctgcaacgcagtagagcctacgaaggaagccctaaaagtcggcccgcttggttgcaaaag
ctggaagctgttttgccgtctcctcaacgtccaattcggcgtttttggcgccgctatcac
atcggaaaactgctaatgattctgattggaactcttgtcttactcttaggatcatacttg
ttttacttatcaaaaacagctaaagtatctgatttacaagatgccttgaaggctacaacg
gttatttatgatcacaaaggagagtatgcaggcagtttatctggtcaaaaagggagttat
gttgagctcaacgctatttcagatgatcttgagaatgctgttattgccactgaggatagg
actttttacagtaatagcggtattaatcttaaacgcttcttattggcggtagttacggcg
ggccgctttggaggtggctcaacgattacacagcaactggctaaaaatgcttatctctca
caagatcagacaattaaacgaaaggcccgagagttttttttggcgttagagttgaccaaa
aaatacagtaaaaaagatattcttactatgtaccttaacaactcctactttggaaatgga
gtttggggagttgaagatgccagtcaaaaatattttggaaccacagctgctaacttaaca
ctggatgaagctgccacattagcaggtatgctcaaaggacctgaaatatataacccttac
cattctctaaaaaatgctactcaccgtagagatactgttttaggagcgatggttgatgcc
aaaaagattacccaaacaaaagctcagcaagctagagcagtagggctaaaaaatcgctta
gctgatacttatgttggtaagacagatgactacaaatacccatcctactttgatgctgtt
attagtgaagcaatagcaacttatggtctttcagaaaaagacattgttaataatggatac
aaagtttacactgagctagatcaaaattaccaaactggcatgcagacgacttttaacaac
gatgaactatttcctgtttcagcttatgacggtagctctgctcaagcagctagtgttgct
ttagatcctaaaacaggaggtgttagaggtctgattggtcgtgtgaatagtagtgaaaat
ccgactttcagaagttttaactatgcgactcaagcaaaacgtagtcccgcatcaacaatc
aaaccactcgtggtttacgcgccagccgttgcttcaggatggtcaattgaaaaagaacta
ccaaataccgttcaagatttcgatggctatcagccacataattatggaaattatgaatca
gaagatgttcctatgtatcaagcattagcaaactcttataatattccagcagtttctaca
ttgaacgatatcggaatcgataaagcctttacctatggtaaaacatttgggttagatatg
agctctgccaaaaaagagttgggggtagctttaggtggcagcgtgacaaccaatccattg
gagatggctcaggcatatgctgcctttgccaataatggagtaatccatcctgcgcacttg
attaaccggattgaaaatgccaggggtgaagtgcttaaaacctttactgataaggctaaa
cgtgttgtcagccagtctgttgcagataagatgacagccatgatgctaggtaccttttca
aatggaacagcagtcaatgctaacgtatatggctatacactagctggtaaaacagggacg
acagaaaccaacttcaatcccgacttagcaggcgatcagtgggttattggttatacgcca
gatgttgttattagtcaatgggtaggatttaatcagaccgatgaaaatcattatctaacg
gattcaagtgcaggcacggcctcagctatttttagcactcaggcatcttacattttgcct
tataccaagggcagccaatttcatgtagataatgcctacgctcaaaatggtatttcagct
gtttatggagtcaatgaaacaggtaatcaatcaggagttgatactcaatctattattgat
ggtttaagaaaatcagcacaagaagcttcgcaatcactatcaaaagcagtcgatcagtca
gggttacgtgataaagcccaatctatttggaaagagattgttgactattttagatag
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