Streptococcus pyogenes STAB901 (serotype M44): STAB901_06050
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Entry
STAB901_06050 CDS
T03472
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spyo
Streptococcus pyogenes STAB901 (serotype M44)
Pathway
spyo00550
Peptidoglycan biosynthesis
spyo01100
Metabolic pathways
spyo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spyo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
STAB901_06050
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
STAB901_06050
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
STAB901_06050
Enzymes [BR:
spyo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
STAB901_06050
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MurT_C
Motif
Other DBs
NCBI-ProteinID:
AIG50566
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Position
complement(1158498..1159889)
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AA seq
463 aa
AA seq
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MKLTLHEVAKIVDAQNNVSDLDDVPLYHIEFDSRKITKGDLFLPLKGQRDGHEFIDLAFQ
NGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDVIAVTGSNGKTSTKDMIGA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHMGDIRLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMDSNGILIAPGDSIIDPYLPENQMVIRFGGHQ
ELNVTDIREEKDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVADEDIIEALE
SVQLTANRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKKIAVLADMKEL
GKDSVILHSQLIDSLTSGNIDQLVFYGDHIKELARLASQVYPAKQVHYFLKTEQEDQFEA
MAQYVQNILNPFDQILLKGSHSMSLEKLVDRLVTDKNCDSYQP
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaaccttacacgaagtggctaaaatagttgatgcccaaaataatgtgtctgac
ttagacgacgttcctctgtatcacattgaatttgatagccgaaagattacaaaaggagac
ctctttttacccttaaaaggtcaaagggatggtcatgagtttattgatttagcctttcaa
aatggagctgtcgctactttttcagaaaaagaattgccggggaaacctcaccttcttgtt
gaagactgcctaaaagcttttcaaaagctagcccattattatattgataagatgcgcgtg
gatgttattgctgtgacaggctcaaatggtaaaacttccaccaaagatatgataggagct
gtcctatcaaccacttacaaaacttacaaaacgcaaggaaattacaataatgagattggt
ttgccttacaccgttctccacatgcctgacgatacggaaaaaattgttcttgaaatggga
caagatcacatgggagatattcgtcttctgtctgaaattgcaaggcctcgtattgcagtt
ttaaccttagtcggcgaagcccatttagaatattttgggtcacgtgacaagattgctcaa
gggaaaatgcaaattgttgatggaatggattcaaatggcattttaattgccccaggtgat
tcgattatcgatccttatcttccagaaaaccagatggtcattcgatttggcggccaccaa
gaattgaatgttactgatattcgagaagaaaaagatagcttaacgtttacaacaaatgtg
ttagcaacacctgtgtccctacctctaccaggaaaatacaacgcgaccaatgctatggta
gcagcctatgttggcaaattgttggcagtagcagatgaggatattatcgaggcgttagag
tctgttcaactcactgctaatcgtacggagtggaaaaaagcagccaatggtgctgatatt
ttatcagatgtctacaatgctaacccaacagccatgcgtctgattttagaaacatttgct
aacatagcaaagaaccccggaggaaaaaagattgcagtgctagcagatatgaaagaactt
ggaaaggattcagtgatacttcattctcagttaattgacagcttaacatcaggtaatatt
gatcagcttgttttttatggggatcatattaaagaattagcacggttggcaagtcaggtt
tatcctgctaagcaagtacattattttttaaaaactgaacaagaagaccagtttgaagcc
atggcacaatatgttcaaaacattcttaatccctttgatcaaattcttttaaaaggcagc
cactcgatgtcgctagaaaagttagtagatcgattagtgactgacaagaattgtgacagc
tatcagccttga
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