Streptococcus pyogenes MGAS5005 (serotype M1): M5005_Spy0023
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Entry
M5005_Spy0023 CDS
T00262
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spz
Streptococcus pyogenes MGAS5005 (serotype M1)
Pathway
spz00230
Purine metabolism
spz01100
Metabolic pathways
spz01110
Biosynthesis of secondary metabolites
Module
spz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
M5005_Spy0023
Enzymes [BR:
spz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
M5005_Spy0023
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
GATase
Svf1_C
Motif
Other DBs
NCBI-ProteinID:
AAZ50642
LinkDB
All DBs
Position
36792..40565
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AA seq
1257 aa
AA seq
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MSSYFPVAPLSDLVSYMNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIEALPGQFDQRAASSQEAL
LLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFSVSDK
TIPNLDFFETYQADDFATYKAEQGLAMEVDDLLFIQNYFKSIGCVPTETELKVLDTYWSD
HCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYER
ANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGA
IRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGYSSYGNQIGLATT
YVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGKTGRDGVGGATGSSK
VQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDFGAGGVCVAIGELADGL
EIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPNDVDAFIAACNKENIDAVVVATVTEK
PNLVMTWNGEIIVDLERRFLDTNGVRVVVDAKVVDKDLTVPEARTTSAETLEADTLKVLS
DLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESSVQKLPVQHGVTTTASVMAQGY
NPYIAEWSPYHGAAYAVIEATARLVATGADWSRARFSYQEYFERMDKQAERFGQPVSALL
GSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAFGVTTADSRKVLSPEFKAAGENIYY
IPGQAISEDIDFDLIKDNFSQFEAIQAQHKITAASAAKYGGVLESLALMTFGNRIGASVE
IAELDSSLTAQLGGFVFTSAEEIADAVKIGQTQADFTVTVNGNDLAGASLLAAFEGKLEE
VYPTEFEQTDVLEEVPAVVSDTVIKAKETIEKPVVYIPVFPGTNSEYDSAKAFEQVGASV
NLVPFVTLNEVAIAESVDTMVANIAKANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRA
AIDSFIEKGGLIIGICNGFQALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRI
ANTNSPWLAGVEVGDIHAIPVSHGEGKLVVSASEFAELRDNGQIWSQYVDFDGQPSMDSK
YNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIPGNKDQILFASAVKYFTGK
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcctattttccagtcgctcccttgtcggacttggtatcttatatgaataaacgt
atttttgttgagaaaaaggctgactttggtattaaatcggctagtcttgtgaaagagttg
acgcataatctacaactgacctctttgaaggctttgcgtattgtgcaggtctatgatgtc
ttcaatttggctgaggatttgctggcgcgtgctgagaagcatattttctctgagcaggtg
acagactgtcttttgacggaaactgaaatcactgcggagcttgataaggttgccttcttt
gccattgaggcgcttcctggtcaatttgaccaacgtgctgctagttcgcaagaagctttg
ctattatttggaagtgacagtcaggttaaggtcaatacagcccagctatacttggtcaat
aaggatattacagaagcagagcttgaagccgttaagaactatcttttgaaccctgttgat
tcgcgtttcaaggacattactttgccgcttgaagagcaggctttctctgtatctgataag
acgatccctaatcttgatttctttgaaacttatcaagctgacgattttgcgacttataag
gcagagcagggcttggctatggaggtcgatgaccttctcttcatccaaaattatttcaaa
tcaatcggatgtgtgccaactgagactgagttgaaagttttggatacttactggtcagac
cactgccgtcacacaacctttgaaactgaattgaagaacattgatttttcagcttctaaa
ttccaaaaacaattgcagacaacttatgacaaatatatcgccatgcgtgatgagcttggt
cgttctgaaaagccacaaacacttatggatatggcgactatttttggtcgttatgagcgt
gccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcctgctcagttgag
attgaagtagatgttgatggtgtgaaagagccttggctcctcatgtttaagaacgagact
cacaatcacccaacagaaattgagccattcggtggagcggcgacttgtatcggtggtgct
attcgtgacccattgtcaggacgttcatacgtttatcaggctatgcgtatttcaggcgca
ggcgatatcacgactccgattgcggaaacacgtgctggtaaattgccacaacaagttatt
tctaaaactgcggcgcacggctattcttcatatggtaaccaaattgggcttgcgacaact
tatgtgcgcgagtacttccaccctggcttcgtagccaaacgtatggagcttggagctgtg
gttggtgctgcacctaaggaaaatgtggttcgtgaaaaaccagaagcaggcgatgtggtc
atcttgctcggtggtaaaacaggtcgtgatggtgtcggtggtgcgacaggttcatctaag
gttcaaacggttgaatctgtggaaacagctggcgcagaggtacaaaaagggaatgccatt
gaagaacgtaagattcaacgtcttttccgtgatggcaatgtcactcgtcttattaagaaa
tcaaatgacttcggtgcaggtggtgtctgtgttgccatcggtgaattggctgacggtctt
gaaatcgatttggacaaggtgcctcttaaataccaaggtcttaatggtactgaaattgca
atctcagaatctcaagagcgtatgtcagtcgttgttcgtccaaatgatgtggatgccttc
atcgcagcctgcaacaaggaaaatatcgatgcagtcgttgttgcgaccgttactgaaaaa
ccaaatcttgtcatgacttggaatggcgaaatcatcgttgatttggaacgccgtttcctt
gataccaatggtgtccgtgtcgttgttgatgctaaagtcgttgacaaggacttgacagtt
ccagaagcacgcacaacatcagcagagacacttgaagcagatacgcttaaggtcttgtct
gacctcaaccacgctagtcaaaaaggtcttcaaactatctttgactcatctgttggtcgt
tcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgacagaaagttctgtt
caaaaattgccagttcaacatggtgtgacaacaactgcatctgttatggctcaaggttac
aatccttatattgcagagtggtcaccttatcacggtgctgcctatgctgtcattgaagcg
acagctcgcttggtagcaacgggtgctgactggtctcgtgcacgtttctcttaccaagag
tactttgagcgtatggataaacaggcagagcgttttggtcagccagtatcagctcttctt
ggttctattgaggctcagattcaacttggtttgccatcaatcggcggtaaggactctatg
tctggtactttcgaagacttgacagtaccaccaaccttggtagctttcggcgtgacaaca
gcggacagccgcaaggttctctctcctgagtttaaagcggctggcgaaaacatttactat
atcccaggtcaagctatttcagaagatattgattttgaccttatcaaggataactttagc
cagtttgaagctattcaagctcaacataagattacagctgcctcagccgctaaatacggt
ggtgtcctagaaagtcttgctctcatgacttttggtaaccgtatcggtgcttctgttgaa
attgcagagcttgacagcagcttgacagctcaactcggaggttttgtctttacatcagct
gaggaaattgctgacgcggtgaaaatcggtcaaactcaggcagactttacagtcactgtc
aatggaaatgaccttgctggcgctagccttctagcagccttcgaaggcaaattggaagag
gtttacccaacagaatttgagcagacagatgttcttgaagaagttcctgctgtggtatca
gatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttacattccagtcttc
cctggtaccaactcagaatacgattcagctaaggcctttgaacaggttggagctagtgtc
aacttggtaccatttgtaaccttgaatgaggttgctattgctgagtcagttgacactatg
gttgctaatattgctaaggcaaatatcatcttctttgctggaggtttctcagcagcggat
gaaccagatgggtctgctaagtttatcgtcaatatcttgcttaacgagaaggtccgcgca
gctattgacagcttcatcgaaaaaggtggccttatcatcggtatctgtaatggtttccaa
gcccttgttaaatcaggtcttcttccatacggaaacttcgaggaagctggtgagacaagt
ccaactctcttctataatgatgctaatcagcatgttgccaagatggttgagactcgtatc
gcaaataccaactcaccttggttggcaggagttgaggtcggcgatattcatgccattcca
gtttcacatggtgaaggtaaacttgttgtcagcgcttctgaatttgcagagctaagagac
aatggtcaaatctggagccaatatgtggactttgacggacaaccatctatggattctaaa
tacaatccaaacggctctgtcaatgccatcgaagggattaccagcaagaatggtcaaatc
atcggtaagatgggacactcagaacgctgggaagacggactcttccaaaatatccctggt
aacaaagaccaaatcctctttgcaagtgctgtaaaatactttacagggaagtaa
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