Streptococcus pyogenes MGAS5005 (serotype M1): M5005_Spy0025
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Entry
M5005_Spy0025 CDS
T00262
Symbol
purM
Name
(GenBank) phosphoribosylformylglycinamidine cyclo-ligase
KO
K01933
phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.3.1
]
Organism
spz
Streptococcus pyogenes MGAS5005 (serotype M1)
Pathway
spz00230
Purine metabolism
spz01100
Metabolic pathways
spz01110
Biosynthesis of secondary metabolites
Module
spz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
M5005_Spy0025 (purM)
Enzymes [BR:
spz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
M5005_Spy0025 (purM)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
Motif
Other DBs
NCBI-ProteinID:
AAZ50644
UniProt:
Q9A1Z0
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Position
42208..43230
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AA seq
340 aa
AA seq
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MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLSKTGVKEPVLV
SGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYIATGKNNPVKLEE
VVSGVAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVGVAEKSQIIDGSKVKEGDIL
LGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLKDVLLEPTRIYVKAALPLIKEEL
VKGIGHITGGGFIENIPRMFADDLAAEIDEDKVPVLPIFKALEKYGDIKHEEMFEIFNMG
VGLMLAVSPENVNRVKELLDEPVYEIGRIIKKADASVVIK
NT seq
1023 nt
NT seq
+upstream
nt +downstream
nt
atgtctgaaaaaaatgcttatgcaaaatctggtgttgatgttgaagctggttatgaagtg
gttgaaagaataaaaaaacacgttgctcgtacagaacgtgcgggagtcatgggagctcta
ggtggctttggtgggatgtttgacttgagtaaaacaggagttaaagagcctgtcttggtt
tcagggactgacggtgtcggaacaaaacttatgcttgctatcaagtacgacaagcacgac
acaatcggtcaagactgtgttgccatgtgtgtcaatgatattattgcagcaggtgctgag
ccattatattttttagattatattgcgacaggaaaaaataacccagtcaaacttgaagaa
gttgtttctggtgttgcagaaggttgtgttcaagcaggagcagcactcattggaggtgag
accgctgaaatgcctggaatgtatggtcaagatgattatgaccttgcaggctttgctgtt
ggtgtggctgaaaaatctcaaatcatcgacggttcaaaagtaaaagaaggcgatattctt
ttgggacttgcttcaagtggtatccattcaaacggttattctttggtacgtcgtgtcttt
gctgactatactggtaaagagctgcttccagagcttgaaggcaaacaacttaaggatgtc
ctccttgagccaactcgtatctatgttaaagcagctctgccattaatcaaggaagaacta
gtcaaaggtatcggccacatcacgggtggtggctttatcgagaatattcctcgtatgttt
gcggatgatttggctgcggaaatcgatgaggacaaggtgccagtgcttccgattttcaag
gcgcttgaaaaatatggtgacatcaagcacgaagaaatgtttgaaatcttcaatatgggt
gtcggtcttatgctagctgttagtcctgaaaatgttaaccgcgtcaaagagctcttggat
gaaccagtttatgaaatcggtcgtatcatcaagaaagcagacgctagtgtggtgattaaa
taa
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