Streptococcus pyogenes MGAS5005 (serotype M1): M5005_Spy0927
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Entry
M5005_Spy0927 CDS
T00262
Symbol
fhs.1
Name
(GenBank) formate--tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spz
Streptococcus pyogenes MGAS5005 (serotype M1)
Pathway
spz00670
One carbon pool by folate
spz00720
Other carbon fixation pathways
spz01100
Metabolic pathways
spz01120
Microbial metabolism in diverse environments
spz01200
Carbon metabolism
spz01240
Biosynthesis of cofactors
Module
spz_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spz00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
M5005_Spy0927 (fhs.1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
M5005_Spy0927 (fhs.1)
Enzymes [BR:
spz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
M5005_Spy0927 (fhs.1)
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
DUF719
Motif
Other DBs
NCBI-ProteinID:
AAZ51545
UniProt:
Q99ZI9
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All DBs
Position
complement(916269..917939)
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AA seq
556 aa
AA seq
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MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLILVT
AINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPME
DINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVG
LGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKV
EGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAG
FGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANL
KRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALA
KTVVRVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFAEFGWD
KLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPA
AMAMDVAENGTALGLF
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgaaatcagatatcgaaattgcccaaagtgtcgccttacaaccaatcactgacattgtt
aaaaaggttggaatagacggcgatgacattgagctttatggcaaatataaggctaaattg
tcttttgagaaaatgaaagctgtcgaagctaatgagcctggaaaattaatcttggtaact
gctattaaccctactccagcaggagaaggaaaatcaaccatgtctattggactggcagat
gccttaaatcaaatgggaaaaaaaaccatgcttgccttacgtgaaccctcccttggtcct
gttatggggattaaaggcggggcagcaggtggtggttatgcccaagtattgcctatggaa
gacattaatcttcactttactggtgacatgcatgccattacaaccgctaataatgcatta
tctgctttgattgacaatcatttgcagcaaggaaacgatttaggaattgatcctcgccgc
attatttggaagcgcgtgttggaccttaatgatcgtgctcttcgtcaggtaattgttggc
ttaggtagtccagtgaatggtgtgccacgcgaagatgggttcgatatcacagtagcttct
gaaatcatggcaattttatgtttggcaactgacttaaaagatctaaagaaacgtcttgct
gatatcgttgtggcttatacctatgatcgtaagcctgtctatgtgcgtgacttgaaggtt
gaaggagccttgacattaattctaaaagatgctatcaagccaaacttggtgcagactatt
tatggaacaccagctcttattcatggggggccatttgctaatattgctcatggttgtaat
tctgtccttgctacctcaacagctttgcgattagcagattacactgttaccgaagcagga
ttcggggccgacctaggagctgaaaaattcctaaatatcaaagtacctaatcttcctaaa
gcaccagatgctatcgttattgttgcaaccttgcgcgcccttaaaatgcatggaggtgtc
gccaaatcagatttagccgctgaaaattgtgaggctgttcgcttaggatttgccaactta
aaacgtcacgtggaaaacatgcgccaattcaaagttccagttgtggtggctatcaatgaa
tttgtagcagataccgaggctgaaattgctaccttaaaagcgctttgtgaagagattaag
gttccagtagaattagccagtgtttgggcaaatggagctgagggaggcttagcattagct
aaaacagtggttcgtgtgattgatcaagaagctgctgactacaaacgtctctattcagat
gaggatactttggaagaaaaagtgatcaatatcgttacccagatttatggtggcaaagct
gttcaatttggccccaaggccaaaacacaattgaagcagttcgcagaattcggttgggat
aaattgcctgtttgtatggctaagacccaatacagtttttcagataacccatccttgctt
ggagcgccaaccgattttgacattaccattcgtgaatttgttcctaaaacaggagcaggt
tttattgttggtttaacaggtgatgtgatgaccatgcctggtttgcctaaagttccagct
gccatggcaatggatgtagcagaaaatggcacagccctcggtctcttttag
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