Streptococcus pyogenes MGAS5005 (serotype M1): M5005_Spy1774
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Entry
M5005_Spy1774 CDS
T00262
Symbol
fhs.2
Name
(GenBank) formate--tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spz
Streptococcus pyogenes MGAS5005 (serotype M1)
Pathway
spz00670
One carbon pool by folate
spz00720
Other carbon fixation pathways
spz01100
Metabolic pathways
spz01120
Microbial metabolism in diverse environments
spz01200
Carbon metabolism
spz01240
Biosynthesis of cofactors
Module
spz_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spz00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
M5005_Spy1774 (fhs.2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
M5005_Spy1774 (fhs.2)
Enzymes [BR:
spz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
M5005_Spy1774 (fhs.2)
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
Motif
Other DBs
NCBI-ProteinID:
AAZ52392
UniProt:
Q99XR2
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All DBs
Position
1736123..1737796
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AA seq
557 aa
AA seq
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MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDARQLVALKNKPDGKLILV
TAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPM
EDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVD
GLQGKVNGIPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLK
AGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPN
LDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGGRE
LAEKVVTLAEQDNQFRFVYEEDDSIETKLTKIVTKVYGGKGINLSSAAKRELADLERLGF
GNYPICMAKTQYSFSDDAKKLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVP
ASETIDIDEEGNITGLF
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atggttttatcagatattgaaatagccaactctgtcactatggaacctatcagtaaggtt
gccgatcaattagggattgacaaggaggcgctctgtctctatggtaagtacaaggcaaaa
attgatgcccgtcaactggtcgccttaaaaaacaaacctgatggcaaactcattcttgtc
actgctatctcaccaacaccagctggtgaaggcaaaaccaccacttctgttggattggta
gatgctctttctgccattggaaaaaaagcagttattgcccttcgtgaaccttctcttggt
cctgtttttggggttaagggaggagctgctggcggtggccacgcgcaagttgtcccaatg
gaagacatcaaccttcactttacaggggactttcatgccatcggtgtcgccaacaactta
ttagctgccttgattgataaccacattcaccatggcaatagcctaggcattgattccaga
cgtatcacttggaaacgtgtggtggatatgaatgaccgccagcttcgtcatattgttgac
ggcttgcaaggcaaggtcaacgggattcctcgtgaagatggttatgacattaccgtcgcc
tctgaaatcatggcaatcctgtgcctatccgaaaatatttctgacctcaaagcccgcctt
gaaaaaatcatcatcggttacaactaccaaggtgaacctgtaacagctaaagacttgaaa
gctggtggtgccctagccgctctgctcaaggatgcgattcatcctaatctcgtgcaaacc
ctggaacacacaccagccctcattcacggtggcccatttgctaatatcgcccatggctgt
aatagtgtcctcgccaccaaactagccttgaaatatggtgattatgccgttaccgaagct
ggatttggcgctgaccttggagctgaaaaattcattgacatcaaatgccgcatgtcaggc
cttcgcccagcagccgttgtcctagtagccactatacgtgcccttaaaatgcatgggggt
gtgccaaaagcagacctggctactgaaaatgttcaggccgttgtggatggtttacctaac
cttgacaaacatttggctaatatccaagacgtctatggccttccagttgtcgtggcgatc
aataaattcccgcttgataccgatgccgaattacaagctgtctatgatgcctgcgacaaa
cgtggcgttgacgttgtgatttctgatgtttgggcaaatggcggagctggtggccgtgaa
ctggctgaaaaagtcgtgacactagccgagcaagacaatcaattccgctttgtttatgag
gaagacgatagcattgaaaccaaactgactaaaatcgttaccaaagtttacggtggtaaa
ggcatcaacttgagctcagcagccaaacgtgaactggctgacttagaacgcctcggcttt
ggcaactacccaatttgcatggccaaaacccaatattccttctcagacgatgccaaaaaa
cttggcgcaccaactgactttacagtgactattagcaaccttaaagtgtccgcaggagca
ggatttatcgttgccctaacaggtgctatcatgaccatgcctggccttccaaaagtacct
gccagcgaaacaattgatattgacgaggagggcaacatcacaggactattctaa
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