Serratia quinivorans: E4343_13215
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Entry
E4343_13215 CDS
T05941
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
squ
Serratia quinivorans
Pathway
squ00260
Glycine, serine and threonine metabolism
squ00261
Monobactam biosynthesis
squ00270
Cysteine and methionine metabolism
squ00300
Lysine biosynthesis
squ01100
Metabolic pathways
squ01110
Biosynthesis of secondary metabolites
squ01120
Microbial metabolism in diverse environments
squ01230
Biosynthesis of amino acids
Module
squ_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
squ_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
squ_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
squ00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
E4343_13215 (thrA)
00270 Cysteine and methionine metabolism
E4343_13215 (thrA)
00300 Lysine biosynthesis
E4343_13215 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
E4343_13215 (thrA)
Enzymes [BR:
squ01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
E4343_13215 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
E4343_13215 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QBX67081
LinkDB
All DBs
Position
complement(2817140..2819599)
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI
LPNMSDAERIFADLLSGLAQALPGFEYDRLKTLVDQEFSQLKQVLHGVALLGQCPDSVNA
AIICRGEKLSIAIMEGVFRAKGFPVTVINPVEKLLAQGHYLESTVDIAESTLRIAAAAIP
ADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTV
PDARLLKSMSYQEAMELSYFGASVLHPRTIAPIAQFQIPCLIKNTANPQAPGTLIGGENL
DTDTPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRAGISVVLITQSSSEYSISF
CVPQSELQRARRALEDEFYLELKDGLLEPLDVMEQLAIISVVGDGMRTLRGISASFFSAL
ARANINIVAIAQGSSERSISVVVSNDSATTGVRVCHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIYRQQPWLKQKHIDLRVCGIANSRAMLTNIHGIALDSWRDELAGAQEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLADGFHVVTPNKKANTSSMNYYQQLRTAAAGSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELTRFSGILSGSLSFIFGKLDEGMSLSAATLEA
KAKGYTEPDPRDDLSGMDVARKLLILAREAGYKLELADIEVESVLPPSFDASGDVETFMA
RLPELDKEYARNVANATEQGKVLRYVGAIENGRCQVRIDAVDGNDPLYKVKNGENALAFY
SRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcggaacctcggtagcgaatgcagaacgttttctgcgcgtc
gccgacatcatggaaagtaacgcacgtcagggacaggtggccacggtcttgtccgctccg
gctaaaatcaccaaccacctggtggcgatgattgataaaacggtagcggggcaggacatt
ctgccaaatatgagcgatgcagaacgcatctttgccgacctgctgagcggtctggcacag
gcgttgcccggttttgaatacgatcgtctcaagacgctggtcgaccaggagttttcccaa
ctcaaacaggtactgcatggcgttgcgctgctggggcaatgcccggatagcgtgaatgcg
gctatcatctgccgcggtgagaagctctctatcgccatcatggaaggggtgtttcgcgcc
aaaggtttcccggttacggtgataaacccggtggagaaactgctggcgcaggggcattac
ctggagtccacggtagacattgccgaatccacactgcgcatcgccgccgcagcaatcccg
gcggatcacatcgtgctgatggccggtttcaccgccggtaacgataaaggggaactggtg
gtgctgggccgtaacggctccgactactctgctgcggtactggctgcctgcctgcgcgcc
gactgctgtgagatctggaccgacgtcgacggcgtttatacctgcgatcctcgtaccgtg
ccagacgccaggttgctgaaatcgatgtcgtatcaggaagctatggagctttcctatttc
ggcgccagcgtgcttcacccccgtactatcgctccgattgcccagttccaaatcccttgc
ctgatcaaaaataccgccaacccgcaggcccctggcacgctgattggcggcgaaaatctg
gataccgataccccggtgaagggcatcaccaatctcaataacatggcgatgatcaacgtc
tccgggccagggatgaagggcatggtcggcatggccgcgcgcgtgtttgccgtgatgtcc
cgtgccggaatctcagtggtgttgatcacccagtcctcttccgaatacagcatcagcttc
tgcgtaccgcagagtgagctgcagcgtgcccgtcgcgcactggaagacgaattctatctt
gaattgaaagatggcctgctagagccgctggacgtgatggagcagttggcgattatctcg
gtcgtcggcgatggcatgcgcaccctgcgcggtatttcggccagcttcttctccgccctg
gcgcgcgccaacatcaatattgtcgctattgcccaggggtcctccgaacgttccatctcg
gtggtggtcagcaacgactcggcgactaccggggttcgtgtctgtcaccagatgctgttt
aacaccgatcaggtgattgaagtgtttgttatcggcgttggcggcgtcggcggtgcgttg
atcgaacagatctaccgtcaacagccgtggctgaagcaaaagcatatcgacctgcgggtg
tgcggcattgccaattcacgcgccatgttgaccaacatacacggcatcgcgctggatagc
tggcgtgatgaactggccggtgcgcaggagccattcaaccttggccgtctgatccgcctg
gtgaaggagtaccacctgctgaatccggtgattgtcgattgcacctccagccaggcggtg
gccgatcaatacgccgatttcctggccgatggtttccacgtggtgacgccgaacaaaaag
gccaacacttcgtcgatgaactactaccaacaactgcgcaccgccgctgccggttcacgt
cgcaagttcctgtacgataccaacgtcggtgcggggttgccggtgatcgaaaacctgcaa
aacctgctgaacgccggtgatgagctgacacgcttctctggcattctgtccggttcgctg
tcgtttattttcggtaagctcgatgagggcatgtcgctgtcggccgcgaccctggaggcc
aaagccaagggctataccgagccggatccgcgtgacgatctttccggtatggatgtggcg
cgcaagctgctgatcctggcgcgtgaggcgggttacaaactggagttggccgatatcgaa
gttgagtcggtgctgccaccttcctttgacgcttccggcgacgtggaaacctttatggcg
cgcctgccggagctggataaagagtacgcccgcaacgtggccaatgccaccgagcagggt
aaggtgctgcgctatgtcggggcgatcgaaaatggccgctgtcaggtgcgtatagatgcg
gtagacggtaacgatccgttgtataaagtgaagaacggcgagaacgccctggctttctac
agccgctactatcagccattgccactggtgctgcgcggctacggtgccggtaacgatgtg
accgccgcaggggtatttgccgacctgttgcgcacactgtcatggaagttgggagtttaa
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