Streptomyces qinzhouensis: FQU76_21240
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Entry
FQU76_21240 CDS
T06686
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
sqz
Streptomyces qinzhouensis
Pathway
sqz00230
Purine metabolism
sqz00670
One carbon pool by folate
sqz01100
Metabolic pathways
sqz01110
Biosynthesis of secondary metabolites
Module
sqz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sqz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
FQU76_21240 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
FQU76_21240 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sqz04147
]
FQU76_21240 (purH)
Enzymes [BR:
sqz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
FQU76_21240 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
FQU76_21240 (purH)
Exosome [BR:
sqz04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
FQU76_21240 (purH)
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
QDY78619
UniProt:
A0A5B8IMA2
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Position
4855996..4857570
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AA seq
524 aa
AA seq
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MTVEAPPSGKRPIRRALVSVYDKTGLEELARGLHEAGVQLVSTGSTAGRIAAAGVPVVKV
EDLTGFPECLDGRVKTLHPRVHAGILADLRLDAHREQLEELGVEPFDLVVVNLYPFRATV
ASGAGYDECVEQIDIGGPSMVRAAAKNHPSVAVVTSPGRYADVLAAVADGGFDLTARRGL
AAEAFAHTAAYDVEVANWFAAQAPAVDSGGDFPEFLGAAYQRAGVLRYGENPHQGAALYV
DGKGGLPGAEQLHGKEMSYNNYTDTEAAWRAAWDHSEPCVAIIKHANPCGIAIGADVAEA
HRKAHACDPLSAFGGVIAVNRPVSVAMAEQVAEVFTEVIVAPGYEDGAIEVLAKKKNIRV
LRCADAPASPVELKLIEGGALLQAADRLQADGDSPANWTLAAGDPLSEAELAELAFAWRA
CRAVKSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAGEERARGSYAASDAFFPFPDGA
EILIAAGVRAIVQPGGSVRDELVVEAARKAGATMYFTGTRHFFH
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
gtgactgttgaggctcccccgagcggcaagcggcccatccggcgggcgctggtcagcgtg
tacgacaagaccggtctggaggagctcgcccgcggtctgcacgaggcgggcgtccagctc
gtctccaccggctcgaccgccgggcgaatcgccgcggccggggtgccggtcgtcaaggtc
gaggatctgaccggcttcccggagtgcctggacggccgggtcaagacactgcacccgcgc
gtccacgccggcatcctcgccgatctgcgtctcgacgcgcaccgcgagcagctggaggaa
ctgggcgtcgagccctttgacctggtcgtggtcaacctctacccgttccgggcgaccgtc
gcgtccggcgccggatacgacgaatgcgtcgagcagatcgacatcggcggtccgtcgatg
gtccgcgccgccgccaagaatcacccctcggtcgcggtcgtcaccagccccggacggtac
gcggacgtgctcgccgcggtcgccgacggcggcttcgacctgaccgcgcgccggggcctg
gccgccgaggcgttcgcccacaccgccgcgtacgacgtggaggtcgccaactggttcgcg
gcccaggccccggcggtggactccggcggtgacttccccgagttcctgggcgcggcctac
cagcgggccggggtgctgcggtacggcgagaacccgcaccagggcgccgcgctgtacgtc
gacggcaagggcgggctgcccggcgccgagcagctgcacggcaaggagatgtcgtacaac
aactacacggacaccgaggccgcctggcgggccgcctgggaccacagtgagccgtgtgtc
gcgatcatcaagcacgccaatccgtgcgggatcgcgatcggcgcggatgtcgccgaggcg
caccgcaaggcgcacgcctgtgacccgctgtccgccttcggcggtgtgatcgcggtcaac
cgcccggtgtcggtggcgatggccgagcaggtcgccgaggtcttcaccgaggtcatcgtg
gccccggggtacgaggacggcgcgatcgaggtgctcgccaagaagaagaacatccgggtg
ctgcggtgcgcggacgcgcccgcgtcgccggtcgagctgaagctcatcgagggcggtgcg
ctgctccaggcggccgaccggctccaggccgacggcgactccccggcgaactggaccctg
gcggccggtgacccgttgtcggaggccgagctggcggagctggccttcgcctggcgggcc
tgccgcgcggtgaagtcgaacgcgatcctgctcgccaaggacggcgcgtccgtcggcgtc
gggatgggccaggtcaaccgggtcgactcggcgaagctcgcggtcgagcgggcgggggag
gagcgggcccggggttcgtacgccgcgtccgacgccttcttcccgttcccggacggggcc
gagatcctgatcgccgccggggtacgggcgattgtccagccgggcggttcggtgcgggac
gagctggtggtcgaggcggcccggaaggcgggcgcgacgatgtacttcaccgggacgcgc
cacttcttccactga
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