Streptomyces qinzhouensis: FQU76_24830
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Entry
FQU76_24830 CDS
T06686
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sqz
Streptomyces qinzhouensis
Pathway
sqz00290
Valine, leucine and isoleucine biosynthesis
sqz00660
C5-Branched dibasic acid metabolism
sqz01100
Metabolic pathways
sqz01110
Biosynthesis of secondary metabolites
sqz01210
2-Oxocarboxylic acid metabolism
sqz01230
Biosynthesis of amino acids
Module
sqz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sqz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
FQU76_24830 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
FQU76_24830 (leuC)
Enzymes [BR:
sqz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
FQU76_24830 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
FQU76_24830 (leuC)
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GFIT
Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QDY79205
UniProt:
A0A5B8JBJ7
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Position
5667271..5668704
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AA seq
477 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLYIDLHLLHEVTSPQAFDGLRMGGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRRNCAEFGVRLHPLGDIEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMARPKTMAITVEGELPDGVTA
KDLILAIIAKIGTGGGQGYVLEYRGPAIEKLSMEARMTICNMSIEAGARAGMIAPDRTTF
DYLQGRPHAPEGADWDAAVAYWETLRTDDDAVFDAEVVIDAAALSPFVTWGTNPGQGAPL
SAEVPDPASYEDASERFAAEKALEYMGLSAGQALRDIHVDTVFVGSCTNGRIEDLRSAAA
VLDGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFTTAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVVGKLASPADLSEADAARTPAGV
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgaaggc
gagcccgacctgctctacattgatttgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccggatgggcggccgccccgtgcgccggctcgacctcaccatcgccacc
gaggaccacaacacccccaccctcgacatcgacaagccgatcgccgacccggtgtcccgc
gcccagctcgaaacgctgcgccgcaactgcgccgaattcggggtacggctccatccgctc
ggcgatatcgagcagggcgtcgtccatgtggtgggcccgcagctcgggctgacccagccc
ggcaccacggtggtctgcggcgactcgcacacctccacccacggcgccttcggtgccctg
gccttcggcatcggcacctcccaggtggagcatgtgctggccacccagaccctgccgatg
gcccgcccgaagaccatggcgatcaccgtcgagggcgagctgcccgacggcgtcaccgcc
aaggacctgatcctggcgatcatcgcgaagatcggcaccggcggcggccagggctatgtc
ctggagtaccgcggccccgccatcgagaagctctcgatggaagcccggatgaccatctgc
aacatgtccatcgaggcgggcgcccgggccggcatgatcgcccccgaccggaccaccttc
gactatctccagggccgcccgcacgcccccgagggcgccgactgggacgcggcggtcgcc
tactgggagaccctgcgcaccgacgacgacgcggtcttcgacgccgaggtcgtcatcgac
gccgccgcgctctccccgttcgtcacctggggcaccaaccccggccagggcgcgccgctc
tccgccgaggtccccgaccccgcttcgtacgaggacgcttcggagcggttcgccgccgaa
aaggccctggagtacatggggttgagcgccggccaggcgctgcgcgacatccatgtcgac
accgtcttcgtaggctcctgcaccaatggccggatcgaggacctgcgctccgccgccgcc
gtcctcgacggccggaaggtcgccgacggggtgcggatgctggtcgtccccggctcggtc
cgggtcgccctccaggccgtcgaggagggcctggacaaggtcttcaccacggcgggcgcc
gaatggcggcacgcgggctgctccatgtgtctggggatgaaccccgaccaactggcgccg
ggcgagcgctccgcgtcgacctccaaccgtaacttcgagggcaggcagggcaagggcggc
cggacccatctggtgtcgccgcaggtcgccgccgccaccgcggtcgtgggcaagctggcc
tccccggccgatctgtccgaagccgacgccgcccgtacgcccgctggagtctga
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