Streptomyces rapamycinicus: M271_24825
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Entry
M271_24825 CDS
T02907
Name
(GenBank) pyruvate dehydrogenase E1 subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
src
Streptomyces rapamycinicus
Pathway
src00280
Valine, leucine and isoleucine degradation
src00640
Propanoate metabolism
src00785
Lipoic acid metabolism
src01100
Metabolic pathways
src01110
Biosynthesis of secondary metabolites
src01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
src00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
M271_24825
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
M271_24825
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M271_24825
Enzymes [BR:
src01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
M271_24825
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AGP56459
UniProt:
A0A0A0NHM5
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Position
complement(6141565..6142731)
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AA seq
388 aa
AA seq
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MTVESTAARKPRRSGAKRSTTARDTKKQPAGQTELVQLLTPEGERVEHPEYAIDPTPEEL
RGLYRDMVLTRRFDAEATTLQRQGELGLWASLLGQEAAQIGSGRALHDADYVFPTYREHG
VAWCRGVDPTNLLGMFRGVNHGGWDPNSNNFHLYTIVIGSQTLHATGYAMGVAKDGADAA
VLAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEKQTRVPLYQRAQGFG
FPGVRVDGNDVLACLAVTKAALERARTGQGPMLIEAFTYRMGAHTTSDDPTRYRSPEERE
LWETKDPILRLRTLLTREGLADDAYFADLERESDALAKRVRDAVRAMPDPEDMAMFEHIY
ADGHALVDEERAQFAEYQASFVTAEEGI
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgcaagccgcgccgcagcggagccaagcgcagcacc
acagcgcgggacaccaagaagcagcctgcgggccagaccgaactcgtacagctgctgacc
cccgagggcgagcgtgtcgagcaccccgagtacgccatcgaccccacccccgaggagctg
cgcggtctgtaccgggacatggtgctgacacggcggttcgacgccgaggccaccaccctg
cagcgccagggcgaactgggcctgtgggcctcgctgctcggccaggaggcggcgcagatc
ggctccggccgggcgctgcacgacgccgactacgtcttccccacctaccgcgagcacgga
gtggcgtggtgccggggcgtcgacccgaccaatctgctggggatgttccgtggggtgaac
cacggcggctgggacccgaacagcaacaacttccacctgtacaccatcgtcatcggctcg
cagacgctgcacgcgaccggctacgcgatgggcgtggccaaggacggcgcggacgccgcg
gtcctggcctacttcggcgacggcgcctccagccagggcgatgtcgccgaatcgttcacc
ttctccgcggtctacaacgccccggtcgtcttcttctgccagaacaaccagtgggccatc
tccgagcccaccgagaagcagacccgggtgccgctctaccagcgcgcccagggcttcggc
ttccccggggtgcgggtggacggcaatgacgtgctcgcctgtctggccgtcaccaaggcc
gcgctggagcgggcgcgcaccgggcagggcccgatgctcatcgaggcgttcacctatcgc
atgggcgcccacaccacctcggacgaccccacgcgctaccgctcgcccgaggagcgggag
ctgtgggagaccaaggacccgatcctgcggctgcgcaccctgctgacccgcgagggcctg
gccgacgacgcgtacttcgccgacctcgagcgggagagcgacgcgctggccaagcgggtt
cgggacgccgtacgggccatgcccgaccccgaggacatggcgatgttcgagcacatctac
gccgacggacatgcccttgtcgacgaggagcgggcgcagttcgccgagtaccaggcttcg
ttcgtcaccgctgaggaaggcatctga
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