Streptomyces rapamycinicus: M271_32185
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Entry
M271_32185 CDS
T02907
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
src
Streptomyces rapamycinicus
Pathway
src00790
Folate biosynthesis
src01100
Metabolic pathways
src01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
src00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
M271_32185
Enzymes [BR:
src01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
M271_32185
6.3.2.17 tetrahydrofolate synthase
M271_32185
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AGP57861
UniProt:
A0A0A0NL00
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Position
7964194..7965699
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AA seq
501 aa
AA seq
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MSEERPQNESDEFEEIVGAETDRDPDLAVIEAGSRTLRAQSGPPQGDGIPARPSDPEVDR
ALREVEGELARRWPETKLDPSLVRIESLMDILGSPQRAYPSIHITGTNGKTSTARMIESL
LGAFELRTGRYTSPHVQSITERISLDGAPISAERFIETYQDIRPYIEMVDAQQEHRLSFF
EVLTGMAYAAFADAPVDIAVVEVGMGGSWDATNVIDAGVAVIMPISLDHTDRLGTTPEQI
AVEKAGIVKQDATVVLAQQPVEAASVVLKRAVEVDATVAREGMEFGVLSREVAVGGQLLT
LRGLGGEYTDVFLPLHGAHQAHNAAMALAAVEAFFGVGSQHARPLDIDTIRSAFASVTSP
GRMEVVRRSPTVVLDAAHNPAGARAAAAAVTESFDFSRLIGVVGASDGKDVRGLLEAFEP
IFAEVVVTGNSSHRAMDPDELAAIAVEVFGSDRVQVEPRLDDALEAAITLAEEEGEYAGA
GVLVTGSVITVGEARLLLGKG
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaggagcgcccccagaacgagtccgacgagttcgaagagatcgtcggagccgag
accgaccgcgaccccgatctggcggtgatcgaggccggcagccggacgctgcgtgcgcag
tccgggccgccgcagggagacggcatcccggcccgcccgtccgaccccgaggtggaccgc
gccctgcgggaggtggagggcgagctggccaggcgctggccggagaccaagctggacccg
tcgctggtgcggatcgagtcgctgatggacatcctcggctcgccgcagcgggcctatccg
tcgatccacatcaccggtacgaacggcaagacgagcaccgcccgcatgatcgagtcgctg
ctgggcgccttcgagctgcgcaccggccggtacaccagcccccatgtccagtcgatcacc
gagcggatcagtctggacggggcgccgatctccgccgagcggttcatcgagacgtaccag
gacatccggccgtacatcgagatggtcgacgcccagcaggagcaccggctgtccttcttc
gaggtgctcaccggcatggcgtacgcggccttcgcggacgcgccggtggacatcgcggtg
gtcgaggtcggcatgggcggctcctgggacgccaccaacgtgatcgacgcgggcgtcgcg
gtgatcatgccgatctcgctggaccacaccgaccggctcggcaccactccggagcagatc
gccgtcgagaaggccggcatagtgaagcaggacgcgaccgtggtgctcgcgcagcagccg
gtggaggccgcctccgtggtgctcaagcgcgcggtcgaggtggatgccacggtcgcccgt
gagggcatggagttcggcgtgctgtcccgggaggtggcggtcggcggccagctgctgacc
ctgcgcggcctcggcggggagtacaccgatgtcttcctcccgctgcacggcgcccaccag
gcgcacaacgcggcgatggcgctggcggccgtggaggcgttcttcggcgtcggctcccag
cacgcccgtccgctcgacatcgacaccatccgctccgccttcgcctccgtgacctcgccc
ggccggatggaggtcgtgcgccgcagccccaccgtggtgctggacgccgcgcacaacccc
gcgggcgcccgtgccgccgccgcggcggtcaccgagtccttcgacttcagccggctgatc
ggcgtggtcggcgcgagtgacggcaaggacgtgcgcggtctgctggaagccttcgagccg
atcttcgccgaggtcgtggtgaccggcaattccagccaccgcgccatggacccggacgag
ctggccgcgatcgccgtcgaggtcttcggctccgaccgggtgcaggtcgagccgcggctg
gacgacgctctggaggccgccatcaccctggcggaggaagagggcgaatacgccggagcg
ggcgttctggtgaccgggtcggtgatcacggtcggcgaggcccggctcctcctgggaaag
ggctga
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