Salpingoeca rosetta: PTSG_08020 Help Entry PTSG_08020        CDS       T04136                                  Name (RefSeq) uncharacterized protein   KO K22754   E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27] Organism sre  Salpingoeca rosetta Brite KEGG Orthology (KO) [BR:sre00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:sre04121]     PTSG_08020 Enzymes [BR:sre01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      PTSG_08020 Ubiquitin system [BR:sre04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    Other single Ring-finger type E3     PTSG_08020 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-C3HC4 zf-RING_2 zf-C3HC4_2 AAA_7 zf-rbx1 zf-RING_UBOX zf-C3HC4_3 AAA_5 zf-C3HC4_4 zf-ANAPC11 zf-RING_5 TRAF3_RING Motif Other DBs NCBI-GeneID:  16071604 NCBI-ProteinID:  XP_004991042 UniProt:  F2UHS1 LinkDB All DBs Position Unknown AA seq 5042 aa AA seqDB search MERRRQIIHMLGGHPAFGRCCDADGKGKWLPNAETRLPEQHDDDDNDSDDVDDDDDDDEE EEEEEELRDASNRGSDYSYYTKDFILRVPSPTTIPYKLFKKSTFPEWQPGYDRVVVIEDD KTAHVHVFSDFATDNQQLHAKAIRFFIQRFLRRDDNDGALRALLNMTSMHVLMDDVLNDT ALIKALTGHQVLRLLTMIDTSSLVGELQSRQGHPSTRVLIQRALVSDPNTIQLFSANNPN LLHDHLQLLAALINTSTSSTYSYDRDAGYNDLCFVILVLGLAPNFEAEKLKHRAELPTTN SSSNTNSHDDHDDHDDHDHDHHSNGGSSSSSVEYSQDDILDAADFVQKYHETIHISADTM MWLAARAILAQLTPKDAIFFAATHPASKVLSEHDPSKFGRVVRTALTNTGGKGTKKKKKK KKRAAGTSGAYLKYMSTLPQAQEHIFDVWLSQLPSIGNDADHPLAKGAIKLATSAQLTSD QRGRLMQMLMNNTRSSMCRLILGSVLHIIPDHLTPVTVIAGMWSVVSPAEVETGLRTWLK EEATKMRVVTVDDPDSDTSGASSSSSRSPATSASATVFTSRRNRNGKGRARRRHRQRAQH QQHHQQHHQQHHQHQQPRIKTVKELSVRSLIHLAVQLEDTLREQLGVISSIPAGRPAEVA ARMHKFKPIYLLAGDCVEESNVPLVAFFQQLIAASSEDGIQLTEKGTTPNHLFGLAANRA VALARQHRQAGDEELCNLLKVLRTAARQNDSHHDMFRRVGVDMLSELTIPQTFKDVTDQP ALWRLVLNMRSPRDWRQTQPAVSARQTLAREYEAWRDLTKTPADMAVLFPPAQEPGRRLS KIHTLANLLAIVAPSDQEELLVLIQEALSVYDQLCDERWTVYSLHKFASDILPSNPWVAS LPATLETWLTEPLSQVNDSNRWNTAENILKESRDLLTALHQRANSHTFRRMLATEMASVH SSYTPATPSASDASETNESNENDDSGLSETTTSTSTTAASPSPPPSSPSTARADDEQVMT DAKREVEQVLKTADKVKTQHTRLFNNLRSSTQLSDLHIMWGGLTRAQVEHDMTLLCTIIG HPSEVRTRGPFAQLTKQLISYAEQRHYAQRAEQLNRVLHVCRPFFVTPVSKLTSAIDAVL DVDDSQTLRHLHTAVQDVQSHVPDDPDVWEVLGEMADAGNLLEFLREQEGDIRHYTASAD TFGSDAYMATAEQVNAFILLHSFMFPLINADTKAKDLEDFLRLLSQRFHQSQGHAASSSG ATSGSASSSASSARQPDRLPLSQLLRICNQGLEALQLFVNTLSDRGAAARERIRLVVDPS VEGARIVFRCDSLRQTASYHICIRHRSEDIELSERDVSDLRARACLLSTDQDQDVRVHMQ RFRDLVEGVELAMAELKQLAESGHLEEFNCYTHAMAVQGANLKDYRNALQTRLLLWTERL KEMREHYDVLNIFSNRQLVVLFHALVQPHEHHDEELVQERDQLLLAMLGPHADVHQVSLF VRDGLNSMGACDDNVHRLSELLAMLKSLIDAPPPRALRPSGMIDESMLPPFRHAAKHDLV RVLLSEDDRTTAASILAAFTDANLEYLPAQCLFCSEHTRVAIVRLFLARSQETTDLPFVL VYPELLSIEAQAELKEELTKWGHRCSNPRSSKPFAPAVGEHVPESSRPLPRFTVVCRRTT RSRLLHGVAGLVDEDLTGHVAQQLLANYALHTREHGAVTVVASEYAQQGKSTFIQQHLAR LAGGSNGASDGDDDGDGDSGRGSGRVGRRGPLRSSMLSRTSQATTATTATTKTGGSGADG GDDLVDDDEGDGDASPALFSSDDDGEDDEFLDASFEFPVPPSGPVPAGMATTATLPRDAV AGDGGHYCTLLVSGQDTFDVLHDKLSRLPLMDPRVKALYIDVGAALNIEDDLNMHLFQLL VLRCLSRDDRLWHVPRHVAVYVEIGNTLHDRLSQQLALTTKAPFADEVAASTTQAAPAQT GAPTASFTKEVLGWDANNIHVPTDTSSPIQRACRYLDLLHRDQLTDVVYREPDLNAMDGI EPTPLSKGDCIRLLTQYFPRLQENHASFGELNTFLLVAAQQLPRMLTSVFLRLSELCGWV GRSRSRAHEIRRGMLMAVVNTVQRFAMPSVDAVKDVQHHHQDAAGTVTDDVLRQMEKAIT WAEMEHWMLCVADDGCVCAFYSDPNSVPPQVRRFFALQRHPLKQMHEYTSQELFVQLKQL LGHKTQAAQNWYAMTPDNLLKMVLIYIRITNNVPCILMGHAGCGKTSLFHQLAHMCNDVV YERPLGIHAGTTAQDIIDYVNEAIDLGEKLLQDAGCVDVAVVPQAGVGAGTQGQTNDQTA TSATAEQDGDADPNAPGSASTSSATNTRVVSQGNDGDDPQGQTNDQVATSATSATGEQDG DADPNAPGSASTSSTTTSSASCTSTPVMPAHPVTVWAFLDEINTCEHLELLSDIIVRRRC GSRSIPDNVKIAAACNPYKRRDRPAPTPGLVTMERQPIDAQSHLMYRVHPLPEAMLPYVW DFGELSAGDERLYMGSMVDGLGLNRDEKKAVVEMLYQCHDYLRKKTGHIISLRDVKRFCT LFKFFQKWRQQRAPFPSPGPRPRETTIPFMSSKMHAAWLSLIQCYVVRLPEQSKRNELLD QCSARFRAWKRWGREAILRLLREEQLDMVDRMDRRAPQFQNLAENAALLENTFSIVVSLL NRIPIFLIGKPGNSKTVSMSLVNNSLRGRDSRDPLLKLYPGITVFAYQGSVEATSEGILQ VFARAEAYLDSANHQDVLPVVVLDEVGLTEHSRHNPLKVLHAKLEPPDGSELRVGVVGIS NWALDAAKMNRALHISRPDPSREDLLHTAVTIASNFVTTEYRFYEGPTRACDLPDELQLP LKGVAFGYHDYMQECKAQNRQPFFGLRDFYSVCKSMCRRMSELNASEGVVATAIIRNFSG TLGGDTVHSDRQLFFTRVQEQLLQVGWYHADRLAVTLMNASHNTVACIEDNWQDVFARHL MIGSVGRAALSILKTFSSLDTSNALIIRGSQFEADVVSEEYPYSVLSQIILKMEHGGVLV LVDLDSIYGSLYDMLNQSYTMIKGRRNCTIALGSLSNPLCPVHERFRCVVLMDREKMQTY DPPFLNRFEKHLLSFTDVLSGDQRDVCTQVENWLTRIVACGQDTSAVTPQDKARAIPCYG DNLVASLLLKHLASMQAAMASAGSSKTIKRENIRPSRVVRAKPAQLHVTVTHGWQSEQQQ QGMQPGDESWQELLHQQNEGLKMHVPPSYLQQQQQQQQQQQQQQQHAGGATGSRFLRASQ WRLTPDLAQQLQQRIKHSLIDLMTLEFVVSLTQFSDEDKQRVVDVYTHESSHHSLAGLLE WLQWFGAPSGDSGGGDGDEQQGASVRKGDYGDYGDGGGYDGDGGAGGHDDDDAATDEGAA EDDDDEMLEKPSKAKKARQQPLPAQPLRRLLLVTRTSIFYPFREVSECEIVRVSDIKSER MLSLELREALRRAGHHGTVVVQLLLNEFKHLAMVQEKVDGLLAGVDRETRGDAGLNGEHT HGGQGCSRVIVCVHMHSKTTSLRKQAQEVAMLQTITASAEWELRYCDDLGSLPSFAAQAL QQEQHTQHVSGGGDDVGGASMHVPAGPSAPPVVEPTLNLIELCSHSLQDVVLRHDHSLLH YRRLITPDALWWCYSRIDFSRVPHCQQRARSSIDRLLAALTSQDQEGEQLCMILAHAAAL MLDSTTTWVAQLAQQDMKQPSYATFGQRVVRTAREAFLSALARIIFSMEQHHFVPDVRQL VPDDATRALLAQLEISPRAYAVLALDALPSTARAFAASTAQHEQPVVDNEGDADDISPAT TSVLRPVSLRLPETHRWYNSLCALAEALFAEMDAAPTEQTRASHVQGFIARVRDAFSHAI AAGVSTDDVTLDIMDTQDDDDGDMDDVDDMDEREDDDDDDDDDDDVDELDANGDDDDDGD ESGNGFGDMSQVHNAAAVVGPLLLVDWVRYANNHVGANVLDIWRGLCLCFGDDISITSDE HVFQVLKKLQENEQMLYAFFSLLSIARRSDARGDVLQVALNSINDTNIGGDDADGDDNDA ESSPGRPTGTSAIVHGICESIALRFIAAITRQQDDDDDEDDDAEDDDDDDDYSGDDDEGE DEANEAMGMVFAARDVMQHLLALPCDASGGRAAITPQIMARVRLLNAILHAWSRNSDLEV VPLLQAFMHLSLTPAHTEPYAAPVTATATGSPSQQLLRFLQQSFDEDKPLWSVGSERRRL VSDTVALFSQMLHLNYAEMTAQEQRTTLAQLCRMVTRAAMTFCPICLVTAVNVSTECGHR FCHQCIVEWAQARRTCPSCRRVLNVANLTPIESEEDDGGAGIGGQTSNHFWLPHVGHAVH TAVLHFAGGHREVHELFQQAPGPLFEALSAVMSHDNFDATQSPPMLVLAVDVLERFVVER AINGCSLIAILHMEHHLQPCVNAVQEVMSNVGDGMGGISPAQARDGVVGIAVLRTCVRVI ARALLDHDVADLETLTDVLPVLFGGDDDGDGFASGVNDSMSVIQRMRLFLLQLLKQGRSF AELRTQLHVLPLCSAIVPLVAWYTRVRLHFQGKLARDKVQGEGAMTHAQAVAEMQAAGVE DAQSRFDAFMAAWNRIVAHQALLFEGETMTEDGSVVQDDEAPHGRFECEPLQPFPPMSPA APLAYSLLSDRGEGSRLYIMLHQLTHVQNQHMDRVVNLCEPGTAAHRAVQQGPAGQVLVQ SVDVTKARPHQVVSVVVDDGVVAHAYAHTALGHGRRTIVNWQAVENMVLQHTFVGKVKFE RVDPAKCGFLFGQEQGVPFLELCDRLFTAHKQYCRSITPERVRAMIESSNFQPSIHDLRS KLEVLMSQLNDHLLGMGGDASGVGNLLCRTTLAEFALMARPVDATSLALLQSCGCHDLAV GQLFALFELVYEQLIFQESRGHTPLEDEADGAIVRDLGEAQRAERFVPAAVMHTLRRFYI THYAQYQHMGDMPLADFWGSLIEEPVFVMDDLANPQQQLQLPDSLLLRHVVPLYVWLHQL PQ NT seq 15129 nt NT seq  +upstreamnt  +downstreamnt atggagagacgccgacaaatcatccacatgctcggaggccatcctgcttttggcagatgt tgcgacgcagacggcaagggaaagtggctgccaaacgccgaaacacggctgccagagcaa catgacgatgatgacaatgacagtgatgatgttgacgatgatgatgatgatgatgaggag gaggaggaggaggaggagttgcgtgacgcaagcaaccgcggcagtgactacagctactac accaaggatttcatccttcgtgttcccagccccacaaccatcccatacaagctcttcaag aaatcaacatttccagagtggcagcctggttacgacagagtcgttgtaatcgaggatgac aagactgcgcacgtgcacgtgttcagcgattttgcaacagacaaccagcagctccatgca aaggcaattcgcttcttcatccagcggtttctgcgccgcgacgacaacgacggcgcgctg cgtgccctgctgaacatgacatcaatgcacgtactcatggacgacgtgctgaatgacacc gcactcattaaggctctgacgggtcaccaggtgctgcgcttgctcacgatgattgatact agcagtctggttggcgagttgcagtcacggcagggtcaccccagcacgcgagtcctgatc cagcgcgctctcgtgtccgatcccaacacgattcaactcttctccgccaacaaccccaac cttctgcacgaccacctgcagctgctggctgccctcatcaacacgagtaccagcagcact tactcctacgacagggacgccggatacaatgacttgtgctttgtcatcctcgttctgggg ctcgccccaaactttgaggcagagaagctcaagcacagggccgagctgcccaccaccaac agcagcagcaacaccaactcacacgacgaccacgacgaccacgacgaccacgaccacgac caccacagcaacggcggcagcagcagcagctccgtcgagtacagccaggacgacatcttg gatgccgctgatttcgtgcagaagtaccacgagacgatccacatcagcgccgacacgatg atgtggctcgctgctcgcgcaatcctggcacaactgacacccaaagatgccatcttcttc gctgcaactcacccggcgagcaaggtgctgagcgaacacgaccccagcaagtttggcagg gtggtgcgcactgctctcaccaacactggcggcaagggcaccaagaagaagaagaagaag aagaagcgggctgcgggcacatcgggcgcctacctcaagtacatgtccacgctgccacag gcgcaggagcacatcttcgacgtgtggctgagccagctgccatcgattggcaacgacgcg gaccacccgctcgcaaagggtgcgataaagctggcaacgtcggcgcaactcacatctgac cagcgggggcggctcatgcagatgctcatgaacaacacacgaagcagcatgtgccgtctc attcttggttctgttcttcatatcatcccggaccacctcacgcccgtgacggtcatcgcg ggcatgtggagtgtggtgtcgccagcagaggttgagacaggcctgcgcacctggctgaag gaagaagcaaccaagatgcgagtcgtcaccgtggacgaccctgactctgacaccagtggt gcatcgtcgtcgtcatcgcgcagcccagccacatctgcttctgccactgtcttcaccagt cgccgcaatcgaaacggcaaaggcagggcacgtcgtcggcaccgacaacgtgcccaacat cagcagcaccaccagcagcaccaccagcagcaccaccagcatcagcagccacgcatcaag acggtgaaggagctgagtgttcgctcactcattcatttagccgtccagcttgaagacaca ctacgcgagcagcttggtgtaatcagcagcataccagctggcagaccggctgaggtggca gcacgcatgcacaagttcaagcccatttacctgctcgccggcgactgcgtggaagagagc aacgtgcccctcgttgccttcttccaacagctgattgccgcctcaagtgaagacggcatc cagttgaccgagaagggaacgacaccaaaccatctctttggtcttgctgcgaaccgcgct gttgctctcgcccggcagcaccgccaggccggtgatgaagagctgtgcaacctgctcaag gtgttgcgaaccgccgctcgccagaacgacagccatcacgacatgttccgccgcgttggc gtggacatgttgtcagagctcaccatcccgcaaaccttcaaggatgttactgatcaacct gcgttgtggcggctggtgctcaacatgcgctcgccacgcgattggcggcagacgcagccg gcagtgtcagcacgacagaccctggcccgcgaatacgaggcgtggcgtgacctcaccaag acgccagccgacatggcagtgttgtttccaccggcgcaggagcctggcagaagactgagt aaaatccacacccttgcgaaccttctggccatcgtggcaccatctgatcaagaagagctt cttgtcctgattcaggaggcattgagtgtgtacgaccaactttgtgacgaacgttggacg gtgtacagcttgcacaagttcgcctcagacatcctgccttcgaatccctgggtggccagt ttgcctgccacgctggaaacgtggctgacggagccactcagtcaagtcaatgacagcaac cgctggaacactgccgaaaacatcttgaaagagagcagagatttgcttacagcacttcac cagcgcgccaacagccacacgtttcgaaggatgctcgcgacagaaatggcctcagtgcat tcatcatacaccccagccacaccatcagcaagcgacgcaagcgagacaaacgagagcaat gagaatgacgactccggcctctccgaaaccacgacatcaacctcaacaacagccgcatcg ccatcaccaccaccgtcatcgccatcaacagctcgcgctgacgatgagcaggtcatgaca gacgcgaagcgggaggtggaacaggtgctcaagactgcggacaaagttaagactcaacac acacgcttgttcaacaaccttcgaagcagtactcagctgtctgatcttcacatcatgtgg ggagggctcacgcgcgcgcaggtggagcacgacatgacactgctgtgtacaatcattggc cacccatctgaagtccgtacacggggcccgttcgcgcaattgaccaagcagctcatcagc tatgctgagcagcgtcattatgcacagcgcgcagagcaactcaaccgagtgttacacgtg tgcaggccgttcttcgtcacgccagtttcgaagcttaccagtgccatcgacgcggtgctg gacgtggatgactcacagacactccgccacctgcacacggctgtgcaggacgtgcagtca catgtccctgacgatcccgacgtgtgggaggtgcttggtgagatggccgacgcaggcaac ttgctcgagtttctgcgagaacaagagggcgacatacgtcactacacggcgagcgcggac acatttggttccgacgcatacatggccaccgcagagcaggtcaacgccttcatcttgttg cactcgttcatgttcccgctcatcaacgctgacacaaaggcgaaggacctggaggacttt cttcgtcttctcagccagcgctttcaccagagccagggccatgctgcatcctcctcggga gcaacatcaggttcggcgtcgtcgtcagcatcatcggcacgtcagccagaccgcctaccg ctgtcgcaactgctgcgcatctgcaaccaaggcctggaggcgctgcagctgtttgtgaac acgctgagcgaccgcggtgccgctgcccgcgaacgcattcgcctcgttgttgatccctcc gtcgaaggcgcacgcatcgtgttcaggtgcgactcgctccgccagaccgcaagctaccac atctgcatccgccacaggagcgaggacattgagttgtcggagcgcgacgtgagcgacctg cgtgcgcgcgcgtgcctgctgtccacagaccaggaccaggacgtgcgtgtgcacatgcag cggttcagggatttggtggaaggcgtcgagttggccatggcagagctgaagcagctggcg gagagcggacaccttgaagagttcaactgctacacgcacgcaatggcggtgcagggcgcc aacctgaaggactacaggaatgcactgcagacccgcctcctgctgtggacggagcgcttg aaggagatgcgcgagcactatgacgtactcaacatcttttccaaccgccagctggtggtg ctgttccatgcactcgtgcaaccacacgagcaccacgatgaggagctggtgcaggagcga gaccagctgctgctggccatgctcggtccccacgccgacgtgcaccaggtgtcgctgttt gtgcgcgatgggctcaacagcatgggtgcatgcgatgacaacgtgcaccggctgagcgag ctgctggcgatgctcaagtcgctcatcgatgcgccgccaccacgcgcccttcgcccctct ggaatgattgacgagagcatgctgccgccgttccgccacgctgccaagcacgatcttgtg cgggtgctgctgtctgaggacgatcgcacgaccgccgcctccatcctggccgcattcacg gacgccaacctggagtacctgcctgcgcagtgcctcttctgctccgagcacacgcgcgtg gcgattgtgcggctgttccttgcccgcagccaggagacaacagacctgccgtttgtgctc gtgtatccggagctgctcagcattgaagcgcaggcggagttgaaggaggagttgaccaag tggggccaccgctgctccaaccctcgctcctcaaagccattcgcacccgctgttggcgag cacgtgccggagtcaagccgcccgcttccacgcttcaccgtcgtgtgtcgccgcaccacg cgaagtcgcctcctgcatggcgttgcagggctggtggacgaagacttgacggggcacgtg gcgcaacagctgctggccaactacgcgctgcacacgagggagcacggtgctgtcaccgtt gttgccagcgagtacgcgcagcagggcaaatccaccttcatccagcaacacctcgcacgc cttgctggtggcagcaacggtgctagcgatggtgatgatgatggtgatggcgacagtgga cgtggcagtggccgtgttgggcgacgcgggccgcttcgctcgtccatgctctcacgcacg tcgcaagctaccaccgcaaccaccgccacgacgaaaacgggtggcagtggtgctgatggc ggggacgaccttgtggacgacgatgaaggggatggcgacgcatcaccggcgctcttctca tccgatgacgatggtgaagacgacgagtttttggacgcgtcgtttgagttccccgtgcca ccgagtgggcccgtgcctgcaggcatggcgacaacagcaacactcccgcgtgacgctgtt gctggcgatggcgggcactactgcacgctgcttgtctctgggcaggacacgtttgacgtc ctgcacgacaagctgtctcgcctgccgctgatggacccgcgcgtcaaggcactgtacatt gacgtcggggcggcactgaacattgaggatgacctcaacatgcatctgttccagctgctg gtgctgcgctgcctctcgcgcgacgacaggctgtggcacgtgccacgccacgtcgcggtg tacgttgagattggcaacacgctgcacgaccgcttgagccagcagctcgcgctcaccacc aaggcgccgtttgccgatgaagtggcggcatccaccacacaggctgcgcctgcacagacg ggcgcgcccactgcctcttttaccaaggaagtgcttgggtgggacgcaaacaacattcac gtgccaacggatacgagctcccccatccagcgtgcttgtcgctacctcgacctcctgcac agggaccagctcacggacgtggtgtacagggaacctgatctgaacgccatggatggcatt gagccaacaccgctgagcaagggagactgcattcgcctcctgactcaatacttcccgcgc ctgcaagagaaccacgcctcctttggcgaactcaacaccttcctcctcgtcgccgcccag cagctgccgcgcatgcttacaagtgtgttccttcgcctgagtgagctctgcggttgggta gggcgctctcgctcacgagcacacgagattcggcggggcatgctcatggcggtggtgaac acagtacaacgatttgcaatgccctccgttgacgccgtgaaagacgtgcagcaccatcac caggacgcggctgggacggtgaccgatgacgtgttgcggcagatggagaaggccatcacg tgggctgagatggagcactggatgctgtgcgttgccgatgatgggtgtgtttgtgccttc tactcggacccaaacagtgtcccgccgcaggtgcgccgattctttgcacttcaacgccat ccactcaaacaaatgcacgagtacacttctcaagagctgtttgtgcagctcaagcaactg ctgggtcacaaaactcaagcggcccagaactggtatgccatgacaccagacaacctgctg aagatggtgctgatctacatccgcatcaccaacaacgtgccgtgcattctcatgggccac gcaggctgcggtaagacgtcactgtttcatcagctggcccacatgtgcaacgacgtggtg tatgagcggccacttggcatccacgcaggcacaacggcgcaggacattatcgattacgtc aacgaagccatcgatctgggggagaagctgctgcaggacgccgggtgtgttgatgtggcg gtggtgccccaggctggtgttggtgctggtacacaggggcaaaccaacgaccagacagcc acgtcagccacagcagagcaagatggtgatgctgaccccaacgctcccggctctgcatcg acatcgtcagcaacgaatactcgtgtggtatctcagggcaatgatggtgacgatccacag ggtcaaaccaacgaccaggtagccacgtcagccacatcggccacaggagagcaagatggt gatgctgaccccaatgctcccggctctgcatccacttcgtcaacaaccacttcttcggcg tcgtgcacctccactccagtgatgcccgctcatcctgtgacggtgtgggcattccttgat gagatcaacacgtgcgagcacctcgagctgctgtcagacatcattgtgcgccgccgctgc ggctcccgctccatcccggacaacgtgaagattgccgctgcgtgcaacccgtacaagcgc cgtgaccgcccagcgccaacaccaggcctggtcaccatggagcgccagcccattgacgcg cagtcgcacctcatgtaccgcgtgcacccgctgccggaggcgatgctgccgtacgtgtgg gactttggcgagctgtctgctggcgacgagcggctgtacatgggcagcatggtggacggc cttggactcaatcgggacgagaaaaaggctgtggtggagatgctgtatcagtgccacgac tacctgaggaagaagacaggccacataatcagcctgcgtgacgtcaagcgtttctgcaca ctcttcaaattcttccagaagtggcggcagcagagagcacccttccccagtcccggacca agaccgcgcgaaaccaccatccccttcatgtcatcgaaaatgcatgctgcatggctgtca ctcattcagtgctacgttgttcgtcttcctgagcaaagcaagcgcaatgagctgcttgac cagtgcagcgcgcgttttcgggcgtggaaacggtgggggagagaagccattctgcggctc cttcgcgaagagcagctggacatggtggatcgcatggacaggcgggcaccgcagttccag aacttggcagagaacgcggccttgctggagaacacgttttccattgtggtgtcgctgctc aaccgcatccccatcttcctgattggcaagccgggcaacagcaagacggtgagcatgagc ctggtcaacaacagtcttcgtggccgtgactcgcgcgacccgctgctcaagctgtaccct ggcatcaccgtgtttgcgtaccaaggcagcgttgaggcgacgagcgagggcatcctgcag gtgtttgcccgcgcggaagcgtacctggacagcgccaaccatcaggacgtgctgcccgtg gtggtgctggatgaggttggactcacagaacactcgcgccacaacccgctcaaggtgctg cacgccaaacttgagccgccagacggcagcgagctccgtgttggcgtcgtcggcatctca aactgggcgctcgatgcggcgaagatgaaccgcgcactgcacatctcccggcctgatcca tcacgcgaagaccttctccacactgcagtcaccattgcaagcaacttcgttacaacagaa tatcggttctacgaaggtccaacacgagcttgcgatctccctgatgagttgcagctacct ctcaagggggtggcttttgggtatcatgattacatgcaggaatgcaaggcccagaaccgc cagcccttttttggcctccgagatttctacagtgtctgcaagtcgatgtgtcgcaggatg agtgagctgaatgcgagcgagggcgtggtggccaccgccatcatccgcaacttctccggc acgctcggaggcgacaccgtccacagcgaccggcagctcttcttcacccgcgtgcaggag cagttgctgcaagtggggtggtaccacgctgaccgcttggctgtgacgctgatgaatgcg agccacaacaccgtggcatgcatcgaggacaactggcaggacgtgtttgcgcgccacctg atgattgggtccgttggtcgcgcggcgctgtccatcttgaagactttctccagcttggac acgagcaacgccctcattatccgcggcagccagtttgaggcggacgtggtgagcgaggag tacccgtactctgtgctgagccagatcatcctgaaaatggagcacggtggcgtgctggtg ctggtggaccttgattccatctacggtagcctgtacgacatgctgaaccagagctacacc atgatcaagggccggcgcaactgcaccattgccctgggctccctcagcaacccgctgtgc cccgtgcacgagcggttccgctgcgttgtgctgatggatcgggagaagatgcagacgtac gacccgcccttcctcaaccgctttgagaagcacctgctcagcttcacagacgtgttgtcg ggggaccagcgggacgtgtgcacgcaggtggagaactggctcacacgcatcgttgcgtgt ggacaggacacgtccgccgtgacgccacaggacaaggcgagggccatcccgtgctatggc gacaacttggtagcaagcctgctgctcaagcacctggcgagcatgcaggcggccatggcc tcggctgggagcagcaagacaatcaagagagagaacattcgaccaagtcgcgttgtacgt gccaagccggctcagctgcacgtcactgtcacccatgggtggcagtcagagcagcagcag caaggcatgcagcctggtgacgagagctggcaggaattgctgcatcagcaaaatgaaggg ttgaagatgcatgtgccaccaagctatctccaacagcaacagcaacagcaacagcaacag caacagcagcaacaacatgccggtggtgcgacgggaagccggttcctgcgcgcatcgcag tggcgcctgacccccgacctggcacagcagctgcagcaacgcatcaagcacagcttgatt gacctgatgacgcttgagtttgtggtgtccctgacgcagttttcggacgaggacaagcag cgcgtggtcgacgtgtacacgcatgaatcctcgcaccactccctcgcgggcctgttggag tggctgcagtggtttggtgcaccgtcaggggatagtggtggtggggatggtgacgaacaa caaggggccagtgtgcgcaagggcgattatggcgattatggcgatggtggtggttatgat ggcgatggtggtgctggtggtcatgatgatgacgacgccgccactgatgaaggtgccgct gaagacgatgacgatgagatgctggagaagccaagcaaggcgaagaaggcacggcagcag ccgctgccggcccagccgctgcgccgcctgttgctggtgacgcgcaccagcatcttctat cccttcagggaggtgtcggagtgtgagattgtgcgtgtgtccgacatcaagtctgagcgc atgttgtcgcttgagctgcgagaagcactgcgccgcgccggccaccacggcacggttgtg gtgcagctgctgctcaacgagttcaagcacctggccatggtgcaggagaaggtggacggc ctgctggctggcgttgaccgggagacgcgcggcgatgctggtctcaacggtgagcacaca catggtggccaggggtgcagccgcgtgattgtgtgcgtgcacatgcactccaagacgacg agcctccgcaagcaagcgcaggaagtggccatgctgcagaccatcaccgcgtctgcggag tgggagctgcgctactgcgacgatctcggctcgctgccctcctttgctgcacaagccctg cagcaggagcagcatacgcagcacgtgagcggtggcggtgatgatgttggcggtgcgtcg atgcatgtgccagctgggccatcggcgccacctgttgttgagccgaccctcaacctgatt gagctgtgctcgcactctctgcaggacgtggtgctgcgccacgatcattcgctgctgcac taccggcgcctgatcaccccagacgcgctgtggtggtgctactcgcgcatcgacttctcg cgcgtgccgcactgccagcagcgtgcgcggtcctcaatcgaccggctgctggccgcgctc acgtcccaagaccaggagggcgagcagctgtgcatgattttggcgcacgcggcggcgctg atgctggattccaccacgacgtgggttgcacagctggcgcagcaggacatgaagcagcca agctacgccacgtttgggcagcgtgtggtgcgcacggcgcgtgaggcattcctgtctgcg ctcgcacgcatcatcttcagcatggagcagcaccactttgtgcccgatgtgaggcagctt gtgcctgacgatgccacgcgcgcgctgcttgctcagctcgagatttccccgcgggcgtac gccgtgctcgcactcgatgcactgccgtccacggcgcgcgcatttgccgctagcactgcg cagcacgagcagccagttgttgacaacgagggcgacgcggatgacatttcgcctgcaacc acaagtgtgctgcgccccgtgtcactgcggctcccagaaacgcatcgctggtacaacagc ctgtgtgcgctggcagaggcgctatttgccgagatggacgcggcgcccacggagcagacg cgtgccagccacgtgcaggggttcatcgcacgcgtgcgtgacgccttttcgcacgccatt gcggccggtgtgagcaccgacgacgtcactcttgacatcatggacacacaggacgatgat gatggcgacatggacgacgtggacgacatggacgagcgcgaggacgatgatgacgatgac gatgatgacgatgatgtggacgagttggatgcgaatggcgatgatgatgatgacggtgac gagagcgggaacgggtttggtgacatgtctcaggtacacaacgcagctgcggttgttggg ccgttgttgctggtggactgggtgcgctatgccaacaaccacgttggcgccaacgtgctg gacatctggcgcggtctgtgcctgtgctttggggacgacatcagcatcacctccgatgag cacgtgtttcaggtgctgaagaagctgcaggagaacgagcagatgctgtacgcgttcttc agcctgctgtcaattgcccgccgctctgacgcacgcggtgacgtgttgcaagttgccctc aactccatcaatgacaccaacattggtggtgacgacgctgatggcgatgacaatgatgct gaaagcagtcctggccggcccacgggcacatctgccatcgtacacggcatctgtgaaagc atcgcactgcgcttcatcgctgccatcacccgccaacaagacgacgacgacgatgaggat gatgatgctgaggacgatgatgatgacgacgattacagtggtgacgatgatgagggtgag gatgaggccaatgaagccatgggcatggtgtttgctgcccgcgatgtgatgcagcacctg cttgccctgccgtgcgatgcgagcggcgggcgtgcggccatcacgccccagatcatggcg cgcgtcaggctcctcaacgccatcctgcacgcgtggagcagaaacagcgacctggaggtg gtgccgctgctgcaggcattcatgcacttgtcgctgacaccagcccacaccgagccgtac gcggcgccggtgacagcaacagcaacggggtcgccgtcgcagcagctgctcaggttcttg cagcagagcttcgacgaagacaaaccactgtggtccgttggtagtgagcgaaggcgcctg gtctccgacacggttgccctcttcagccagatgctgcacctcaactacgcggagatgacg gcacaagagcagcgcacgaccctcgcccagctgtgccgaatggtcacgcgtgcagcgatg acattctgccccatctgcctcgtcactgccgtgaacgtcagcacagagtgcggccacaga ttctgtcaccagtgcattgttgaatgggcccaggcgaggcgcacgtgcccgtcgtgccgc cgtgtcctcaacgtggccaacctcacgcccatcgagagcgaagaagacgatggtggtgct ggtattggtggccagacgagcaaccacttctggctgccgcacgttgggcatgctgtccac acggctgtgctgcactttgcaggtggtcaccgtgaggtgcacgagctattccagcaagcg cctggccccttgtttgaggcactgagcgcggtgatgtcccacgacaactttgatgcaacg cagagcccgcccatgctcgtgcttgccgttgacgtgctggagcgctttgtggtcgaacgc gccatcaacggctgcagcctcatcgccatcttgcacatggaacaccacctgcagccgtgc gtaaatgcggtgcaggaggtgatgagcaacgttggcgacggtatgggtggcatctccccg gcgcaggcacgtgatggcgtggttggcattgctgtgctgcgtacatgcgtgcgtgtcatt gcgcgcgcgctgttggaccacgacgtggccgatttggagacgctgactgacgtgcttcct gtgctgtttggaggagacgatgatggtgacggctttgccagtggtgtcaacgacagcatg agcgtgatccagcgcatgcgcctgttcctgctgcagctgctgaagcaaggccgcagcttt gccgagttgcgcacgcagctgcacgtgctgccgctgtgttctgcgattgtgccgctggtg gcgtggtacacgcgcgttcgcctgcacttccaaggtaaattggcgcgcgacaaggtgcag ggcgagggcgccatgacccacgcgcaagcagtagcagagatgcaggccgctggcgtggag gatgcgcagagccgctttgacgcgtttatggcggcgtggaaccggatcgttgcgcaccag gcgctgttgtttgagggcgagacgatgacagaggacgggtctgttgtgcaggacgacgag gcgccccacggccggttcgagtgtgagccactgcagcccttcccgcccatgtcgcctgca gcgccgctggcgtactcgctgctctctgaccggggagaggggtcccgcctctacatcatg ctgcaccagctcacgcacgtgcagaaccagcacatggaccgggtggtgaacctgtgcgag cccggtactgcggcgcaccgcgctgtgcagcaagggcctgctggccaggtgctggtgcag agcgtggacgtgaccaaggcgaggccgcaccaggttgtctctgtggttgtggacgacggt gtggttgcgcacgcgtacgcgcacacggcgctgggccacggacggcgcacgattgtcaac tggcaggccgtggagaacatggtgctgcagcacacgtttgtcggcaaggtgaagtttgag cgtgttgacccggccaagtgcgggttcctgtttgggcaggagcaaggcgtgcccttcctt gagctgtgcgaccggctgttcacggcgcacaagcagtactgccgctccatcacccccgag cgggtgcgggccatgattgagtcgtccaacttccagccgtccatccacgacctgcgcagc aagctggaggtgctcatgtcgcagctcaacgaccacctgcttggcatgggcggcgacgcg tctggcgtgggcaacttgctgtgcaggacgacgctggccgagtttgcgctgatggcgcgg ccggtggatgccacgtcgctggcgctgctgcagtcgtgcgggtgccacgacctggcagtt gggcagctctttgcgctctttgagctggtgtacgagcaactcatcttccaggagtcgcgt gggcacacgccgctggaggacgaggccgatggcgccattgtccgcgacctgggggaggcg cagcgggccgagcggtttgttcctgccgcggttatgcacacgctacggcggttctacatc acccactacgcgcagtaccagcacatgggtgacatgccgcttgccgacttctggggcagc ctgattgaggagcccgtgtttgtcatggacgacctggcgaacccgcagcaacagctgcag ctgccagactcgctgctcctgcgtcacgtcgtgccgctctacgtctggctgcaccaactg ccgcagtga

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