Spirosoma rhododendri: HH216_10220
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Entry
HH216_10220 CDS
T08048
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
srho
Spirosoma rhododendri
Pathway
srho00260
Glycine, serine and threonine metabolism
srho00261
Monobactam biosynthesis
srho00270
Cysteine and methionine metabolism
srho00300
Lysine biosynthesis
srho01100
Metabolic pathways
srho01110
Biosynthesis of secondary metabolites
srho01120
Microbial metabolism in diverse environments
srho01230
Biosynthesis of amino acids
Module
srho_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
srho_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
srho00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HH216_10220 (thrA)
00270 Cysteine and methionine metabolism
HH216_10220 (thrA)
00300 Lysine biosynthesis
HH216_10220 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
HH216_10220 (thrA)
Enzymes [BR:
srho01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HH216_10220 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
HH216_10220 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT_7
ACT
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
QJD78762
UniProt:
A0A7L5DMK2
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Position
complement(2438714..2441185)
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AA seq
823 aa
AA seq
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MQVLKFGGTSVGSVESIKQVIQIIDSYRRDDGSQPGDLITVVFSAMGGVTNQLIEIGRMA
TTGDTDYMELVRRIEDRHFNVIKALIPVKEQSKVFAQVRGVINELEDLLRGVSLIRELSP
RTLDLITSFGERLSTAVITECIRSRGISAQFLDARTVIKTDDQFGQADVNYPLTNQLIQD
HYAKTDALQLVTGFIGSTDKNETTTLGRGGSDYTASILGAALNAEVIDIWTDVDGMMTAD
PRKVTNAFNIPTITYAEAMELSHFGAKVIYPPSLQPAFARNIPVRVLNTFNPTHEGTLVS
RTAERRQYTITGISSIDDIALVNVQGSGMIGVAGVSAKLFGVLAAHKISVILISQASSEH
SICFALDPRGAENVKAILDSEFATEIAHGHIDNIAIERDLSVIATVGEGMRKSSGIAGKL
FSVLGKNGVNIVAVAQGSSEINISVVINKNNLSKALNALHNIFFQSEARVLNLYLVGTGL
IGKTLLQQIAKQADYLKSEKLLKVCVVGMTNTRKMLLDPKGIDLDDWSERQLAEGVTTSL
PAFVEKIKDYNLPNSVFIDCTSDKDVVQFYESLLDANISVVTPNKVANSGSYAEYRRLQR
TALNRGVKFLYETNVGAGLPIINTVQGLMTAGDQFLKIEAILSGTLSFIFNTFSAGTSFA
DVVREAKTKGYTEPDPRDDLSGQDVARKILILAREAGFPLEPQDVTINNLLPQSCLDAPT
VPAFFDELERNNDYFENLLASADAKGEKLRFVASFENDKAVIELRSVGPEHPFYQLTGAD
NIVSFTTERYKDRPLVVKGPGAGAEVTASGVFADVVSIGSYLA
NT seq
2472 nt
NT seq
+upstream
nt +downstream
nt
atgcaggttcttaagtttggcggtacttcggtagggtccgtagaaagtatcaagcaggtt
atccagattatcgacagttatcggcgcgatgatgggtcgcaaccgggcgatctgattacg
gtggtgttttcggcaatgggtggggtaaccaaccagcttatcgagattggacgcatggcc
accaccggcgacactgactacatggaactggtccggcgcattgaggaccgccatttcaac
gtcattaaagccctgattccggttaaggagcagagtaaagtgttcgcgcaggtgcgtggg
gtaattaatgaactcgaagatctgctacggggtgtctcgctcattcgtgaactgtcgccc
cgcacgctcgacctcatcaccagtttcggcgaacgcctgtcgaccgccgtcattaccgag
tgtatccgcagcagaggtatctcggcgcagtttctggatgctcgcacggtgattaaaacc
gacgatcagtttgggcaggccgatgtaaactacccactgacgaaccagctgattcaggat
cattacgccaaaactgacgccctgcaactggtcactggctttatcggttcaaccgacaaa
aacgagacgaccacactgggtcggggcgggtcagactatacggcgagtatactgggcgcg
gcccttaacgccgaagtcatcgacatctggaccgacgtcgacgggatgatgacggccgat
ccgcgcaaggtgaccaacgccttcaacatcccgaccattacgtacgccgaagcgatggaa
ctcagccacttcggtgccaaagtaatttacccgcccagtttgcaaccggctttcgcgcgc
aacatcccggtgcgggtgctgaacacgttcaatcccacccacgagggtacgctcgttagc
cggacggccgaacggcggcagtacactatcacgggtatttcaagcatcgacgacatcgcc
ctggtcaacgtgcagggttcggggatgattggtgttgcgggggtgtcggccaagctattt
ggcgtactggccgctcacaaaatcagcgtaatcctgatttcgcaggcatcgtcggaacac
tcgatctgttttgcgctcgacccgcgcggggccgagaacgtcaaagccattctcgactcg
gaatttgccaccgaaatcgcccacggccacatcgataacatcgccatcgagcgcgacctg
tcggtgatcgcgacggtgggcgaaggtatgcgcaaatcgtcgggtattgcgggtaagctg
ttttcggtgctgggtaaaaacggggtcaacatcgtggccgtcgcgcagggatcgtcggag
atcaacatctcggtggtcatcaacaaaaacaacctgtcgaaagccctcaacgcgctgcac
aacattttcttccagtcggaagcgcgggtgctgaacctgtatctggtcgggacggggctg
atcggcaagacgctattgcagcagatcgccaagcaggccgattacctgaaatcggagaag
ctgctgaaagtgtgcgtggtgggcatgaccaatacccgtaaaatgctcctcgaccccaaa
ggcatcgacctcgacgattggtcagaacgccagcttgctgaaggtgtcacgacgtcgctg
cccgcctttgtcgagaaaatcaaagactataacctgcccaactcggtattcatcgactgc
acgtcagacaaagacgtggtgcagttttatgagtcgctgcttgatgccaacatctcggtt
gtaacgccgaataaggtggccaactcgggttcgtatgccgagtaccggcggttacagcgc
acagccctaaaccggggtgtcaagtttctgtacgaaaccaatgttggcgcggggttgccg
atcatcaacacggtgcagggcctgatgacagcgggcgatcagtttctgaagatcgaagcc
atcctgtcgggcacgctgtcattcattttcaacacattcagcgcgggtacgtcattcgcc
gatgtcgtacgcgaagccaagaccaaaggctacaccgaacccgacccgcgcgacgatctg
agcggtcaggatgtggcccgcaaaatcctgattctggcccgtgaagctggctttccgctc
gaaccgcaggatgttacgatcaacaacctacttccccaatcgtgcctcgacgcgcctacg
gtacccgctttcttcgacgagctagagcgcaacaacgactacttcgagaacctgctggca
tcagccgacgcgaagggtgaaaaactgcggttcgtagccagttttgagaacgacaaagcg
gtaattgagctacggtctgtcggtccggaacatccgttctaccagttgaccggtgccgat
aacattgtttcgttcacgacggaacgctacaaagatcgccccctcgtggtgaaaggcccc
ggcgcgggtgctgaagtaacggcctccggtgttttcgccgacgtcgtcagcatcggtagc
tatctggcgtaa
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