Streptomyces rimosus: CP984_01765 Help Entry CP984_01765       CDS       T07052                                  Name (GenBank) type I polyketide synthase   KO K19204   pimaricinolide synthase PimS2 Organism srim  Streptomyces rimosus Pathway srim01052   Type I polyketide structures Brite KEGG Orthology (KO) [BR:srim00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01052 Type I polyketide structures     CP984_01765  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:srim01008]     CP984_01765 Polyketide biosynthesis proteins [BR:srim01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Pimaricinolide synthase      CP984_01765 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C KAsynt_C_assoc PP-binding adh_short PKS_DE CurL-like_PKS_C Thiolase_N Epimerase RhiE-like_linker adh_short_C2 PKS_DH_N PS-DH GDP_Man_Dehyd SpnB_Rossmann NmrA Polysacc_synt_2 ACP_syn_III DUF7080 SDR Docking RmlD_sub_bind Motif Other DBs NCBI-ProteinID:  QEV73972 LinkDB All DBs Position complement(461276..489697) Genome browser AA seq 9473 aa AA seqDB search MDQEQKLRDYLKRASADLRRSRQRVGELEAAAREPIAIVGMSCRFPGGVRSPEELWSLLA ADGDGITKAPADRGWEQAAEDAGDFSGGFLHEAAEFDASFFGISPREALAMDPQQRLLLE SSWEAFERAGIDPAAVRGTRTGMFVGAMPQEYRVGPDDDVQGFALTGTTTSVISGRLAYF FGAVGPAVTIDTACSSSLVALHLAAHSLRQGECSLALAAGVTVMSSPTTFVEFSRQGGLS PDGRCRSFADSANGTGWAEGVGVLVLERLSEARRNGHEILAVVRGSAVNQDGASNGLTAP NGPSQQRVIEQALVSARLSADEVDAVEAHGTGTTLGDPVEAQALLATYGQGRDADSPLLL GSVKSNLGHTQAAAGLAGVIKMVLAMKHGLLPRTLHVDAPSSHVDWTQGAVRLLTEQVPW PQGERPRRAGVSSFGLSGTNAHTILEEAPAAPQEDTEEPAAPEPVAAGAVPWLVSGRTRE ALRAQAAQLLEHLASAPAAAPVDVAYSLATARSGMEHRAAFTAADLDRARAALTALADGT PDPGLVQDTARTRSKLAFLFTGQGSQRPGMGRELAARFPAFATALDEVLTHLDQGLDRPL KELLFAEEGTPEAALLDRTGYAQPALFAIEVALYRLAESFGIRPDHLAGHSIGEIAAAHV AGAFSLADAAALVVARGRLMQALPEGGAMISLEATEEEVLPLLEDRRDRVSIAAVNGPAA VVVAGEESEAEAVAEHFAALGRKTKRLRVSHAFHSPLMEPVLEEFRTVVAGLTPQTPVIP VVSGLTGTLATVEQLASPDYWADHARHTVRFADTLAWLDGHGTATYLELGPDGVLSAMAQ SCLAAADDAADGVPATLAVLRKGRPEAETLTAALAGLHTRGVAVQWEPYFQGTGAQRVDL PTYAFQRRRYWPRNVPGAGGDVRAAGLGAAHHPLLAAAVSVANSDGLLLTGRLSRRTHPW LADHAVRGTVLLPGTAFLELAVRAGDEAGCGRVEELTLAAPLVLPEEGGVQVQVWVGSPD ESGRRAVSVHSRPDGPEELPWTQHATGTLVAGEHRADFDATVWPPADARPLDLDGFYDRM ADNGFGYGPLFQGLHAAWRSGDAVYAEVTLPGADGADAASATSFGIHPALLDAALHAAAF ADLGEQARGGLPFAWQDVTLHASGASTVRVKLTPADDDAVAIAVADTSGAPVASIGSLVL RSMPDEELGGAAALVRDALFELRWTEARQAAQAAPAAVAVLGTDLFGLEQALASPDRTVA ALPGLDAITDVPDVILASVAGADGDEVTDAVHARTAHALELLRTWLADERYAASRLVLVT RGAVATGAGQAPDPVAAAVWGLVRAAQSEHPGRFALLDLDPGAAETAAEPLSRALALSAD EPQTAVRGTSVFTARLARAQAPRTAAEWDPEGTVLLTGATGGLGRVLARHLVAERGVRHL LLASRRGADADGAGELVAELTGLGAQVTLTACDLADRAAVDRLLAGVPDAHPVTAVVHSA GTLDDGVIESLTPERISAVLRPKADAVWHLHEATRDLDLAAFVVFSSLSGTVGAAGQGNY AAANAFLDALAQLRRAQGLPGLSLAWGPWAPTAGMTGGLTDDDLDRLARMGTPALTEDQG IALFDAATAADAAVLLPTRLDLSVLRLQDQLPPLWRGLIRTPARRAVVSGSEAAVTLVQR LSRLPETDRREVVLDLVAGQVAGVLGHAGTADIDPRRPLRELGFDSLTAVELRNRLSAAT GLRTAATVIFDHPTVDALATHILDGLMGSAAAAAVQAPRAATDDDPIVIVGMSCRYPGGV ASPEDLWRLVSEGTDAISGLPADRGWDLDALYDPDPDRTGTSYSRFGGFLHDAADFDPAF FGMSPREALATDSQQRLLLEASWEAVERAGIDPVSLRGSQTGVFAGVMYNDYGTVLAGGQ FEGHQGSGTAPSVASGRISYTLGLEGPAVTVDTACSSSLVAMHWAMQALRAGECSLALAG GVTVMSTPGALIEFSRQRGLSPDGRCKAFSDGADGVGWSEGVGVLVLERQSDARRNGHRI LAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALAAAGLTAADIDAVEGHGTGTTLGDPI EAQALLAAYGQERDPESPLLLGSVKSNIGHTQAAAGVAGVIKMVMAMEHGVLPRTLHADE PSSHVEWDSGAVRLLTEETPWPQADRPRRAAVSSFGFSGTNAHLIVEQPPAATEQREQPA LSPAVLPWTLSGKSRAALRDQAARLLSFLDERPALDPADIALSLATTRSAFDQRAVVTGD RDELLRALANLAADRPDSALTEGETGGAGKLAVMFSGQGSQRPGAGRELAARFPAFDRAL DEVAAALDPHLDRPLKDVLFAPEGSPEAELLDRTEWTQPALFAFQVALHRLLGTWGIRPD ILMGHSVGEIAAAHVAGVLSLPDAARLAAARGRLMQELPAGGAMISLEATEDEAAPLLAG REHEVSLAAVNGSRSVVVAGDEAAAEEIAAHFTAQGRKTKRLKVSHAFHSPLMEPVLDGL REVAAQLTYGTPEVTIISGLTGRPVTDDELRSPDYWAAHARGTVRFADTVRAAHARGAGT FLELGPDSTLSAPAQDALGDEADADFLPLLRAGRGEERCAATALARLHVRGTAVDWPAYL AGTGARTVGLPTYAFQHERYWPEPAPARPAQAAADPADAELWGSVERGDAAALADLLGLR DEQHASLYALLPALSSWRQQRHEKALLDSTRYRVAWRPVRAAAAPVLEGTWLLVTADGID SDEILDALRGHGAQFETLVLDAAACRDRAELAARLDAVRTEERAFSGILSLLPLADGPGN RPGAELPAGLALSLVLTQALSDTPLDAPLWTLTRGAVTTGAGDPLTNPLQAAVWGLGRVA ALEHPQLWSGLVDLPATLDAPATQHLVSALAAQGGEDQLAIRATGAFGRRLARHPQAELP AADAFTARGTVLVTGGTGALGAEAARWLARSGADHLLLTSRRGPDAPRAAELAAEIEELG AEVTIAACDTADRDALAAVLASVPAEHPLTGVVHAAGIGQNAALADTPLDEAAAAMAAKM LGAAHLDSLLDDHDLDFFVLVSSIAGVWGSAGQSAYSAANAYLDALAEHRAARGLPATSV AWGPWAEAGMATHEAVTEELRRRGLRFLVPATAMTELRRAVVHRDVTVTVADIDWERYHP VFTSTRRNVFFDELGEVQALVRAENDAESAAPEFAARLRGLAEDEQERLLADLVRAEAAV ALGHDSADAIPERRAFRDAGFDSLTAVELRKRLAALTGLNLPATLVFDYPTPTVLARHLR EEILGTGGAQAAAVAAASGGFDEPIAIVGMSCRFPGGVRSPRQFWELISDGVDAISDFPV NRGWDTGLHHPDPDHPGTTYSSQGGFLHDAGEFDASFFGISPREALSMDPQQRLLLETTW EAFEYAGIDPTTVHGSATGTFIGSTYQEYGLGIEDGSAGHLVTGTSPSVLSGRLAYLFGL EGPAVTVDTACSSSLVALHLACQSLRNGESSLALAGGATVMTNPNPFVAFSRQRALAGDG RCKAFADGADGMTLAEGVGILVLERLSDAQRNGHDILAVVRGSAINQDGASNGLSAPNGP SQQRVIRQALANSGLAPADIDAVEAHGTGTALGDPIEAQALQATYGRDRDPERPLLLGSV KTNIGHTQSAAGVAGVIKMVMALREGTLPRTLHADTPSGHIDWTPGTLALLNEPAEWSEG ERPRRCAVSSFGISGTNAHTIIEEAPRPQETAPTEPVPPAGDAVPWVLSARTPGALRAQA AKLAAHLDGEQAPGALDVAHSLVASRTLFDHRAVVVGTDDTARRAALDALATGGSAPGVV QGTADTDGKTVFVFPGQGSQWVGMGARLLEESPVFAERLTECATALSAFTDWSLLDVLRQ TEGAPTLDRVDVVQPASFAVMVSLAALWSAHGITPDAVIGHSQGEIAAAAVAGALSLEDA ARVVALRSQAIARGLAGSGGMMSVPLPAAEVEQRLAAYEHLSIAAVNGPRSTVVSGATAP LDALQAELVGADIRARRIAVDYASHSAQVEMVRDELHTVLAPVRPRPAEVPFFSTVTGDW LDTTAMDGDYWYTNLRQTVRFQHGIGELLAQGHRFFIEVSSHPVLSIGVQETVEEAGGTA AVLGTLRRDTGGVDRFLTSLAEAFVRGAGADWAAVLADTGARRVPLPTYAFQREHLWAIP ERTGARAETDPADAEFWTAVEQEDVDALASSLRLDQAALAPVLPALSHWRKHRRDLSTVD SWRYHATWKPLTSLPTATLTGSWLVVAPEGTDTDGLTAVLAAHGAEPRTLVLDDACADRA VLAERLTGLGDLTGVVSLLAEAEGRSAAHPALSRGIALTLALVQALGDAGIDAPLWCLTR SAVSTGRADRLTRPEQAQILGLGWTAALEHPQRWGGLVDLPEQLDQRAGERLAAVLTGRT GEDQLALRASGVLARRVVRATPADATPARPWTPRGTTLVTGGTGTLAPHLARWLAGQGAE HVVLTSRRGPDAPGMDELVQELAELGCEAGVVACDLTDRDAVARMLDGLAAEGRTVRTVV HTAVTIELATLEETTHEAFAKVMDAKVTGARHLDELLGDDLDAFVLYSSTAGMWGSGAHA AYVAGNAYLNALAEHRRARGAHATAVSWGIWADDLKLGRVDPTQIRRSGLVFMDPQLALT GLRQALDGDETVLAVADVDWERYHPVFTAARPTRLFEDVPEVQRLEEDTTETADTGSEFA TRLLGLAPVEQDRLLLDLVRTEAATALGHASPDVLSEQRAFRDVGFDSLTAVDLRNRIAS VTGLALPSTMVFDYPNPLALVAFLRESLAGSATGTTATATGTTAADDEPIAIIGMSCRYP GGIGSPEDLWRLVAEGGDATGEFPTNRGWDAEGLYDPDPDRAGHTYSTRGGFLHEATDFD ASFFGISPREALAMDPQQRLLLETSWEAMERAGIDPAALRGSSTGTFIGASYQDYGAGAG SPENAEGHLITGTISSVLSGRLSYTYGFEGPAVSLDTACSSSLVALHLACQSLRNGESSL ALAGGVSIMSTPGAFVGFSRQRAMAADGRCKAYSDQADGMSLAEGVGLVLVERLSDARRN GHQVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAKVDPDGIDVVDGHGTGTAL GDPIEAQALLATYGQGRDPERPLLLGSVKSNIGHTQMASGVASVIKMVMAMRHGAVPRSL HIDRPSSHVDWSSGAIRLLTEPLDWPSTGHPRRAGVSSFGLSGTNVHTILEQAPQEPAED ATDAAPVRPAEPAPVPLVLSGRTEEGLRAQAGRLLSHLADHPGLPLTDLAFSLATSRSAL EHRAAVVTDDPDALTRALTALRDADADGALLTGSPDRGRLAFLFTGQGSQRPGMGRELYD THPVYAQALDAVLARFDLELDRPLRDILFAEPGTPEAELLDDTGYTQPALFALEVALFRL AESWGLRPDYVAGHSIGEFAAAHAAGVLSLEDACTLVAARGRLMAALPPGGAMASVEATE DEVAAVLTAYEGRAAIAAVNTPGSLTVSGDEDAVLAVAAHFKELGRRTKRLRVSHAFHSP HMDPMLADFARAVGSVTCHAPTVPLVSTVTGALLTHEELAAPEYWTGQVRGTVRFADAVR HLTEHGVTTFFELGPDAVLSGAVREGTGEQDRATAVPALRRDRPEAPALTTALARLHLHG VRVDWEAVFAGSGARRIDLPTYPFQRERFWPEPTAGTAAPAQPADEADAEFWSAVERADL ASLGSSLDLDDDTLTAVVPALSSWRRKSRERSTVDGWRYRTTWKALTGPAAGGRPSGTWL VLVPAAGAGEWAEAVIGALGTDAVRIDIAAPQRQELAQRMRELSAEHGGFAGVLALPATA GEGDADPATEGLLLTATAVQALGDAGIDAPLWCVTRTAVAVDRAEHPARPAQAAVWGLGR VAALEHPQRWGGLIDLPDELDSTTLRRLATVLADSGGEDQLAVRTTAAFARRLAHHRVMP DSEAGTFSPTGTVLVTGGTGALGGHVARWLAEAGAQHLLLVSRRGADAPGAGELAAQIED MGVRVTLAACDTADRGALDAVLAEIPEEHPLTAVFHTAGTVDDGTLDTLTPEQFTSVLHA KVTATRTLHEATRDLDLSAFVLFSSVAGTLGAPGQGNYAAANAFLDAFAEHRRAHGLPAT SIAWGPWAEDGMAADGTDVQARIRRGGYNPLPPQLALTALRQAIEQGAPTLTLADIDWQR YAEVFTATRPSPLVGDLPELRQATAPAGTAEAALREPALRQRLAGLSPAARPRFVLDLVR TRVAAVLGHSGTSGIGADRAFSDLGFDSLTTVELRNTLTAATGLKLPATLVYDYPTPIAL ADFLLAELQGALPESDRLAPAPGGRAADDDPIAVVGLNCRFPGGIRSPEDLWQLLGRGED AISGFPADRGWDLDALAQGGSATLEGGFLDGVGLFDAAFFGISPREALAMDPQQRLLLET SWEVFERAGIDPATLRGSRTGVFVGTNGQDYATVLRRATGTADIRGHVATGNTASVLSGR LSYAFGLEGPAVTVDTACSSALVALHMAANALRSGECTLALAGGVSVMSSPDSFTEFTVQ GGLAPDGRCKPFADAADGTSWSEGVGVLVLERLSDARRNGHEVWGIVRGTAVNQDGASNG LTAPSGRAQQRAIRQALADADLAPADIDVVEAHGTGTTLGDPIEAQALITAYGPDRERPL LLGAVKSNLGHTQAAAGVAGTIKMLLAMRHGVLPKTLHVDAPSSHVDWSDGTVSLVTEEQ AWPETGHARRAGVSAFGVSGTNAHVIIEQAPEAEEPEADGPAEPTTVPGLVPWPVSAKSE AALAAQIERITALTGLAPADVGHSLATGRSAFTHRAVLAADGTGVRELARGIAQETDGKL ALLFSGQGAQRAGMGRELYGRFPVFAEALDAVLAHFDAGLRDVIFGDAEGLDETGFTQPA LFAIEVALFRLAESLGIRPDFVAGHSIGEIAAAHVAGVFSLADACALVAARARLMQALPE GGAMVAIEATEGEVGPRLADGVSIAALNGPESVVISGTQDAVLRIAAEFADEGRKTRRLS VSHAFHSPLMDPMLADFRQVAEGLAYEAPRIPLVSNVTGELATAELICTPGYWVQHVRDT VRFADGVRALEAEGASVFLEVGPDGVLTAMAQHSLADAAVAVPALRKDRPEETALLTALA QLYVTGVGIDWSGVFDGTGARRVDLPTYPFQQEWFWPETAPAASPADGSQAPVDAEFWDA VEREDLTALSADLDLDGSALGALVPALSAWRRKRVERSTVDGWRYQVTWKPLTGTSASTL SGPWLALVPAGGADDEWTASVVAALGDDAVSVEADPADSRALTARLAELAAQGQEFAGVV SLLAARTGEGVASGGAAWPDAAVQALADAGIGARLWYVTRGAVAVGRSETDVDAAQAAVW GAGRVAALDHPDLWGGLVDIADVLDRRSADRFRAVLSGTGGEDQVALRSSGAFGRRLVRA TADTPSTPWQPSGTVLVVGGASGTGGLCARWLAGQGAQHILLAGPATPEADTLPAELDGL GAELTRVTCDPADSDALLNALTALPPTAPLTAVVYADAEALSGDGEPGTALAALHTAVEN LAAVAEAAAGERPLDAFVLCSSIAGTWGAGGRGAEAAAGALLDALARRYRARGLRALSVA WGAWADTTDDSLAAHLRVNGLPVMDAERALSALSRSAGTDAASVTVADVRWDRFAPAFTR NRRGALFTDLPEARAALAEPGNAGQGTATGLGARLAGRPAAEQTEALLTLIRGEVATVLG FADADAVPSGPAFKDLGFDSLTAVDLRNQLATATGLSLPATLVFDYPTAEALAGHLRTEL FGEDGDALPAVGAVRARGAADDPVVIVGMSCRYPGGVRSPEDLWQLAMGEVDAIGGFPVD RGWDLETLLNGDRDGRGRTAVREGGFLYDVADFDPGFFGIAPREAMVMDPQQRILLEASW EALERAGIDPAGLRGGDTGVFIGGGSGDYRPEAGQLGHAQTAQSASLLSGRVAYHFGLEG PTVSVDTACSSSLVALHLAAQALRNGECSVALTGGVTVMSSPVNFVEFGEMGALAPDGRC RAFADSASGTGWSEGVGVLVLERLSDARRNGHEILAVLRGSAINQDGASNGITAPNGPSQ RRVIRRALADAGLAPGDVDAVEAHGTGTTLGDPIEAQALLATYGQERELPLYLGSLKSNI GHTQAAAGVAGVIKMVQAMRHGVLPRTLHVDAPSAHVDWDSGAVELLTEAADWPRTDHPR RAGISAFGASGTNSHVIIEQFEQPEPAVTTEPVEAHGPLPVPVSAAAPQALRAQARQLHS YVTARPGLGTADLARALATTRSVFTHRAAVLAGDRDELLAGLAALADGRTAPQVVQGEAA ARRGKLAVLFSGQGTQRLGMGRELYARFPAFAAAFDAVTAHLDTELDRPLRDVLSEDAER LNETGYTQPALFAIEVALFRLVESWGIRPDFAAGHSIGEIAAAHVAGVFSLEDACKVVAA RARLMNALPSGGAMVAVQATEEEVTALLTAGVSIAAVNGPRSVVLSGDEGAVLDIADKLT ADGRKTRRLRVSHAFHSLHMDAILDDFRRVTRSVDYHAPRIPLVSNVTGEAATEEQVCSP DYWVRHVREAVRFGDGIRTLAESGVTAFLELGPDGGLCAMAQDTLDALASRALAVPVLRK DRGEQESAVTALARLYADGAAPDWDALLAGTATGPRRNDLPTYPFQRQRYWPATLPGDAS AAPEGADDGFWTAVREADFASLETTLNVDGEALAKVLPALADWRRRRGEENTVDGWRQQI TWQPLSPQPARTPAGTWLAVLPAGHADDPWAADAVTALGPDTVRLEVADPDRAALAERLR ALAADGFAFTGVVSLLALATTPAPGADAPEALALTTALIQALGDADLAAPLWCVTRGAVA AAPSEPVPGLAQAAVWGLGRVAALEHPQRWGGMVDLPDTLDERSTARFADILAAPGGEDQ IAVRPSAALGRRLVPVPAGRGTAEWDPTGTVLITGGTGALGAHVARRLAEAGARHLLLLS RRGPDAPGAGELRTELTALGAEVTLTACDAADRDALAAVLADIPEEAPLTGVIHTAGVLD DGVLDSLTPDRYEAVFHAKAASALALHDLTRDRDLAVFALFSSSSGAVGNAGQANYAAAN AFLDALAEQRRAQGLAATSIAWGVWGGDGMAADQRAADVARRTGIRPLDPDLAVVALRRA VLDGRPTEVVADIERDRFVRSFTAVRPSPLLGEPAAAGHPAADGAGEDATGDALREKLAG LSPAKRSEAVLDLVRTRAAAVLGHPTADAVGADRAFRDLGFDSLSAVELRNQLGAATGLS LAATLVFDHPSPAGLAAHLLGRLVPEAGTGEGTGDGDPDAAGIRALLASVSLHQLREIGV LEPLMKLAAEQTAAAGGQAAGAPETDAYEESIDAMDVADLVQAALDGNAPEER NT seq 28422 nt NT seq  +upstreamnt  +downstreamnt atggaccaggaacagaaactccgcgactacctgaagcgggccagtgccgatctgcggcgc tcccggcagcgggtgggcgagctggaggcggcggcccgcgagccgatcgcgatcgtgggc atgagctgccgcttcccgggcggcgtgcgcagccccgaggagctctggtccctgctcgcc gccgacggggacggcatcaccaaggcgcccgccgaccgcggctgggagcaggcggccgag gacgcgggggacttctccggcggcttcctgcacgaagcggccgaattcgacgcctccttc ttcgggatctccccgcgtgaggcgctcgccatggacccgcagcagcggctgctgctggag tcctcctgggaagccttcgagcgggccggcatcgacccggcggcggtccggggcacccgg acgggcatgttcgtcggggcgatgccccaggagtaccgggtgggcccggacgacgacgtc cagggcttcgccttgaccggcaccaccaccagcgtcatctcgggccgcctcgcctacttc ttcggggccgtgggcccggcggtcaccatcgacaccgcctgctcctcctccctcgtggcc ctgcacctggccgcccactcgctgcgccagggcgagtgctccctcgcgctggccgccggt gtgaccgtgatgtccagccccaccaccttcgtggagttcagccgccagggcggcctctcc ccggacgggcgctgccgctccttcgcggactccgccaacggcaccggctgggccgagggc gtcggcgtcctggtcctggagcgcctctccgaggcccgccgcaacgggcacgagatcctg gccgtcgtacggggctccgccgtcaaccaggacggcgcctccaacggcctgaccgccccc aacggcccctcccagcagcgggtcatcgaacaggcgctggtcagcgcgcggctctcggcc gacgaggtcgacgccgtcgaggcgcacggcaccggcaccaccctcggcgacccggtcgag gcgcaggcgctgctggcgacctacggtcagggccgcgacgccgacagccccctcctgctg ggctccgtcaagtcgaacctcggccacacccaggcggcggccggcctggccggtgtcatc aagatggtgctggccatgaagcacggcctgctcccgcgcacgctccatgtggacgcgccg tcctcgcacgtcgactggacgcagggggccgtacgcctgctcaccgagcaggtcccctgg ccgcagggtgaacggccgcgccgggccggcgtctcctcgttcgggctcagcggcaccaac gcgcacaccatcctggaagaggccccggccgcaccccaggaggacaccgaggagccggcc gcgcccgagcccgtggcggcgggcgccgtcccgtggctcgtctcgggccgtacccgcgaa gcgctgcgcgcccaggccgcgcagctcctcgaacacctcgcgtccgcccccgccgccgcg ccggtcgacgtggcctactccctggccaccgcccgctccggcatggagcaccgcgccgcg ttcaccgcggccgacctggaccgggcgcgcgccgccctcaccgcgctggccgacggcacg ccggacccgggcctcgtgcaggacaccgcacggacccgctccaagctcgccttcctcttc accgggcagggctcccagcggccgggcatgggccgtgaactcgccgcccgcttccccgcc ttcgccaccgccctcgacgaggtcctcacccacctcgaccagggcctcgaccggccgctg aaggagctgctgttcgccgaggagggcacgcccgaggcggccctgctcgaccggaccggc tacgcccagcccgcgctgttcgccatcgaggtcgcgctctaccgtctcgccgagtccttc ggcatcaggccggaccacctcgccgggcactccatcggcgagatcgccgccgcgcacgtg gccggggccttctcgctggccgacgccgcggccctggtggtcgcccgcggccgtctcatg caggcgctgcccgagggcggcgccatgatctccctcgaagccaccgaggaggaggtcctg cccctcctggaggaccggcgggaccgcgtctcgatcgccgcggtcaacggacccgccgcc gtcgtggtcgcgggggaggagagcgaagcggaggccgtcgcggagcacttcgccgcgctg gggcgcaagaccaagcggctgcgcgtctcgcacgcgttccactccccgctgatggaaccc gtgctggaggagttccgtacggtcgtcgccgggctcaccccgcagacgccggtgatcccg gtcgtctccggcctgaccggcaccctcgccaccgtcgagcagctggcctccccggactac tgggcggaccacgcccggcacaccgtacggttcgccgacaccctcgcctggctcgacggc cacggcaccgccacctacctggaactgggccccgacggcgtcctgtccgccatggcccag agctgtctggccgcggccgacgacgccgccgacggcgttcccgcgacgctcgccgtcctg cgcaagggccgccccgaggccgaaaccctcaccgccgcgctggcgggcctgcacacccgc ggcgtcgccgtccagtgggagccctacttccagggcaccggcgcccagcgcgtcgacctg cccacgtacgccttccagcgccgccgctactggccccggaacgtgcccggggcgggcggc gacgtgcgcgccgccggcctgggcgcggcccaccacccgctgctggccgcggccgtgtcg gtcgccaactccgacggcctgctgctgaccggccggctgtcgcggcgcacccacccctgg ctcgccgaccacgccgtacgcggcaccgtcctgctgccgggcaccgccttcctcgaactg gccgtacgcgccggggacgaggccggatgcggccgcgtcgaggaactcaccctggccgca ccactggtcctgcccgaggagggcggcgtccaggtgcaggtgtgggtgggcagcccggac gagtcgggccgccgcgccgtgagcgtccactcccgccccgacgggccggaggaactgccc tggacccagcacgccacgggcaccctcgtcgccggtgagcaccgcgccgacttcgacgcc acggtctggccgcccgccgacgcgcgtccgctggacctcgacggcttctacgaccgcatg gccgacaacggcttcggctacgggccgctgttccagggcctgcacgccgcctggcgcagc ggcgacgccgtctacgccgaggtgacgctgcccggggccgacggcgccgacgccgcgtcc gccacgtccttcggcatccacccggccctgctggacgccgcgctgcacgccgcggccttc gccgatctgggcgaacaggcccgcggcgggctgcccttcgcgtggcaggacgtgaccctg cacgcgagcggggcgagcacggtccgcgtgaagctgaccccggccgacgacgacgccgtg gcgatcgccgtcgccgacaccagcggcgccccggtcgcctccatcggctcgctggtcctg cggtccatgcccgacgaagagctcggcggcgctgccgccctcgtccgcgacgccctgttc gagctgcgctggaccgaggcgcgccaggccgcccaggcggcgcccgccgcggtcgccgtt ctcggtacggacctcttcggcctggagcaggccctcgcctcgccggaccgtacggttgcg gcgctgcccggcctggacgccatcaccgacgtgccggacgtgatcctcgcgtccgtcgcg ggtgcggacggcgacgaggtcaccgacgccgtacacgcccgtaccgcccacgccctggag cttctgcggacctggctggcggacgagcgctacgccgcgtcccggctggtcctcgtcacc cgtggcgcggtcgccaccggcgccgggcaggcgccggacccggtggccgccgccgtctgg ggcctcgtacgggcagcgcagagcgagcaccccggccgcttcgcgctgctcgacctcgac ccgggtgccgccgagaccgccgccgagccgctgtcgcgcgccctggccctgtccgcggac gagccgcagaccgccgtacgcgggaccagtgtgttcaccgcgcggctcgcccgcgcccag gcgccgcgtaccgcggcggagtgggaccccgagggcaccgtgctcctcaccggggccacc ggcgggctgggccgcgtactggcccggcacctggtcgccgagcgcggcgtacggcacctg ctgctcgccagccgccgcggcgccgacgccgacggcgccggagagctcgtggccgaactg accgggctcggcgcgcaggtgaccctcacggcatgtgacctggccgaccgcgccgccgtt gaccggctgctggccggcgtgcccgacgcgcaccccgtcaccgccgtcgtgcacagcgcc ggaaccctcgacgacggtgtgatcgaatcgctcacccccgagcggatcagcgcggtgctg cggcccaaggccgacgccgtgtggcacctccacgaggccacccgcgacctggacctggcg gccttcgtcgtcttctcctccctgtccggcaccgtgggcgccgcgggccagggcaactac gccgccgccaacgccttcctcgacgcgctcgcccagctgcgccgcgcccagggcctgccg ggcctctccctggcctggggcccgtgggcgcccaccgccggcatgaccggcggcctcacg gacgacgacctcgaccggctggcccggatgggcacccccgccctcaccgaggaccagggc atcgccctgttcgacgcggccaccgccgcggacgccgccgtcctgctgccgacccggctc gacctgtccgtcctgcgcctccaggaccagctgccgccgctgtggcgcggcttgatccgc accccggcccgccgcgcggtggtctcgggctcggaggccgccgtcaccctcgtacagcgg ctgtcccggctgccggagaccgaccgccgcgaggtcgtgctcgacctggtggccggtcag gtggccggcgtcctcggccacgcaggcaccgccgacatcgacccgcggcgccccctgcgg gagctgggcttcgactcgctgaccgccgtggaactccgcaaccggctcagcgccgccacc ggcctgcgcaccgccgcgacggtcatcttcgaccatccgaccgtcgatgccctggccacc cacatcctcgacggcctgatgggctccgcagccgccgccgcggtccaggcaccccgtgcc gccaccgacgacgaccccatcgtcatcgtcggcatgagctgccgctacccgggcggcgtc gcctcgcccgaggacctgtggcggctggtcagcgagggcaccgacgccatctcggggctg cccgccgaccgcggctgggacctggacgcgctctacgacccggacccggaccgcaccggc acctcgtactcccgcttcggcggattcctgcacgacgccgccgacttcgaccccgccttc ttcggcatgagcccccgcgaggcgctggccaccgactcccagcagcggctgctcctcgaa gcgtcctgggaggccgtcgagcgggcgggcatcgacccggtgtccctgcgcggcagccag accggcgtgttcgcgggcgtcatgtacaacgactacggcacggtgctcgccggcgggcag ttcgagggccaccagggcagcggcaccgccccgagcgtcgcctccggccgcatctcgtac accctcggcctcgaaggccccgccgtcaccgtcgacaccgcgtgctcgtcctcgctggtc gccatgcactgggcgatgcaggcgctgcgtgcgggggagtgctcgctcgcgctggccggc ggtgtcacggtcatgtcgacgccgggcgccctcatcgagttctcccggcagcgcggcctg tccccggacgggcgctgcaaggcgttctccgacggcgccgacggtgtcggctggtccgag ggcgtgggcgtactcgtcctggaacggcagtccgacgcccgccgcaacgggcaccgcatc ctggccgtcgtacggggctccgccgtcaaccaggacggcgcctccaacggcctgaccgcc cccaacggcccctcccagcagcgcgtcatccggcaggcgctggccgccgcaggactgacc gccgcggacatcgacgccgtggagggccacggcaccggcaccaccctgggcgaccccatc gaggcgcaggccctgctcgccgcctacggccaggagcgcgaccccgaaagcccgctgctg ctgggctcggtgaagtccaacatcggccacacccaggccgccgccggtgtcgccggtgtc atcaagatggtcatggccatggagcacggcgtactgccccgtacgctgcatgccgacgag ccgtcctcgcacgtggagtgggactccggcgcggtgcgcctgctcaccgaggagacaccc tggccgcaggcggaccggccgcgccgcgccgccgtctcctccttcggcttcagcggcacc aacgcgcacctcatcgtcgagcagcccccggccgccaccgagcagcgcgaacagcccgcg ctgagcccggccgtgctgccctggacgctgtccggcaagagccgggccgcgctgcgcgac caggccgcccgcctgctctccttcctcgacgagcgccccgccctcgacccggccgacatc gcgctctccctcgccaccacccgctcggccttcgaccagcgcgccgtcgtcaccggcgac cgcgacgaactgctgcgcgcgctggcgaacctggccgccgaccgccccgactccgcactg accgagggcgagaccggcggtgcgggcaagctggccgtaatgttctccggacagggcagc cagcgccccggagcgggccgggaactcgccgcccgcttccccgcgttcgaccgcgccctg gacgaggtggccgccgccctcgacccgcacctggaccgccccctcaaggacgtcctgttc gccccggagggcagccccgaggcggaactgctggaccgcaccgagtggacccagcccgcc ctgttcgccttccaggtcgcgctccaccggctgctgggcacctgggggatacgccccgac atcctgatgggccactccgtcggcgagatcgccgccgcgcacgtcgcgggcgtcctctcg ctgcccgacgcggcccgcctggccgccgcgcggggacggctgatgcaggagctgcccgcc ggcggcgcgatgatctccctggaggccaccgaggacgaggccgcgccgctgctcgccggc cgcgagcacgaggtgtcgctcgccgccgtcaacggctcccgctccgtcgtcgtcgcgggc gacgaggccgctgccgaggagatcgccgcccacttcacggcgcagggccgcaagaccaag cgcctgaaggtcagccacgctttccactcgcccctcatggagcccgtcctcgacggcctc cgcgaggtcgccgcccagctcacgtacggtacgccggaggtgaccatcatctccgggctg accggacggccggtcaccgacgacgaactgcgctccccggactactgggccgcacacgcg cgcggcaccgtccgcttcgccgacaccgtgcgcgccgcgcacgcccgcggcgccggcacc ttcctcgaactcggccccgacagcaccctgtccgcccccgcccaggacgccctgggcgac gaagcggacgccgacttcctgccgctgctgcgcgccgggcgcggcgaggagcgctgcgcc gccaccgcgctggcccgcctgcacgtacgcggtacggccgtcgactggcccgcgtacctc gccggcaccggagcccgtacggtcggcctgcccacctacgccttccagcacgagcgctac tggcccgaaccggccccggcccgccccgcgcaggccgctgccgacccggcggacgccgag ctgtggggctccgtcgagcgcggcgacgccgccgcactggccgacctcctggggctgcgc gacgaacagcacgcctccctgtacgcgctgctgcccgccctgtcgtcctggcgccagcag cggcacgagaaggcgctgctggactccacccgctaccgggtcgcctggcggcccgtacgg gcggccgccgcgcccgtgctcgaaggcacctggctgctcgtcaccgccgacggcatcgac agcgacgagatcctggacgcgctgcgcggccacggcgcccagttcgaaaccctcgtactg gacgccgccgcctgccgcgaccgcgcggaactcgccgcccggctcgacgccgtacgcacc gaggagcgcgccttctccggcatcctgtccctgctcccgctggccgacgggcccgggaac cggccgggcgccgaactgccggccgggctcgcgctcagcctcgtactgacccaggcgctc agcgacaccccgctcgacgcgcccctgtggaccctgacccgcggcgcggtcaccaccggc gcgggcgacccgctcaccaaccccctccaggcagcggtctggggcctggggcgtgtcgcc gccctggagcacccgcagttgtggagcggcctggtcgacctgccggccacgctcgacgcc cccgccacccagcacctcgtcagcgcgctggccgcgcagggcggcgaggaccagctcgcg atccgcgccaccggggcgttcggccgtcgcctggcgcgccacccgcaggccgaactgccc gcggccgacgcgttcaccgcgcgcggcaccgtgctcgtcaccggcggtacgggagccctc ggcgccgaggccgcacgctggctcgcccgcagcggcgccgaccacctcctccttacgagc cgccgcggccccgacgctccccgcgcggccgaactcgccgcagaaatcgaggagttgggt gccgaggtcaccatcgcggcctgcgacaccgccgaccgcgacgcgctcgccgccgtcctg gcctccgtacccgccgaacacccgctgaccggcgtcgtgcacgcggccggcatcggccag aacgccgccctcgccgacaccccgctggacgaggccgcggcggcgatggccgccaagatg ctcggcgcggcccacctcgacagcctcctggacgaccacgacctggacttcttcgtcctc gtctcctcgatcgccggcgtgtgggggagcgccgggcagagcgcctacagcgccgccaac gcctacctcgacgccctcgccgagcaccgcgcggcacgcggcctgcccgccacctcggtg gcctggggcccgtgggccgaggccggcatggccacccacgaggccgtcaccgaggagctg cgcaggcgcggactgcgcttcctcgtgcccgcgaccgcgatgaccgaactgcggcgcgcc gtcgtccaccgggacgtcacggtcacggtcgccgacatcgactgggagcgctaccacccc gtcttcacctccacccgccgcaacgtcttcttcgacgaactcggcgaggtccaggccctc gtacgcgccgagaacgacgccgagagcgccgcgcccgagttcgccgcccgcctgcggggc ctggccgaggacgagcaggaacggctgctggccgatctggtgcgcgccgaggcggccgtc gccctcggccacgactccgcggacgccatcccggagcggcgggccttccgcgacgccggg ttcgactcgctgaccgccgtcgaactgcgcaagcggctggccgccctcaccggcctcaac ctgcccgccaccctcgtcttcgactacccgacgcccaccgtcctcgcccgccacctgcgc gaggagatcctgggcaccggcggcgcacaggccgcggccgtggcagccgcatcgggcggc ttcgacgagcccatcgccatcgtcggcatgagctgccgcttccccggcggcgtccgctcc ccgcggcagttctgggagctgatctccgacggcgtcgacgcgatcagcgacttccccgtc aaccgcggctgggacaccggcctccaccaccccgacccggaccaccccggcaccacctac tccagccagggcggcttcctgcacgacgcgggcgagttcgacgcctccttcttcggcatc tcgccgcgcgaggcgctgtccatggacccccagcagcggctgctgctggagaccacctgg gaggcgttcgagtacgccggaatcgaccccaccaccgtccacggcagcgcgaccggcacc ttcatcggctccacctaccaggagtacgggctcggcatcgaggacggctcggccggccac ctggtgaccggcaccagccccagcgtgctgtccgggcgcctggcctacctcttcggcctc gaaggcccggcggtcaccgtcgacaccgcctgctcctcgtccctggtcgccctgcacctg gcctgccagtcgctgcgcaacggcgaaagctccctggccctggccggcggcgcgaccgtg atgaccaaccccaacccgttcgtcgccttcagccgccagcgggccctggccggcgacggc cgctgcaaggcgttcgccgacggcgccgacggcatgaccctcgccgagggcgtcggcatc ctcgtcctggagcgcctgtcggacgcacagcgcaacgggcacgacatcctcgccgtcgtc cgcggctcggccatcaaccaggacggcgcctccaatggcctgtccgcccccaacggcccc tcccagcagcgcgtcatccgccaggccctggccaactcggggctcgccccggcggacatc gacgccgtcgaggcccacggcaccggcaccgccctcggcgaccccatcgaggcgcaggcc ctgcaggccacgtacggccgggaccgcgaccccgagcgcccgctgctgctcggctccgtc aagaccaacatcggccacacccagtcggcggccggtgtcgccggcgtcatcaagatggtg atggccctgcgcgagggaacgctgccgcgcaccctgcacgcggacaccccctccggccac atcgactggacgcccggcaccctcgccctgctgaacgagcccgccgagtggtccgagggc gagcgcccgcgccgctgcgcggtctcctccttcggcatcagcggcaccaacgcccacacc atcatcgaagaggccccccgcccgcaggagacggctcccaccgagccggtgcccccggcc ggtgacgccgtgccctgggtgctgtccgcccgtaccccgggcgcactgcgcgcccaggcg gccaagctcgccgcccacctcgacggcgagcaggcacccggcgcgctggacgtcgcccac agcctggtggcctcgcgcacgctcttcgaccaccgcgccgtcgtcgtcggcaccgatgac accgcacggcgggccgcactggacgccctcgccaccggcggctccgcgcccggcgtcgtg cagggcacggccgacaccgacggcaagaccgtcttcgtcttccccggccagggctcccag tgggtcggcatgggcgcgcggctcctggaggagtccccggtcttcgccgagcgcctgacc gagtgcgccaccgccctgtcggccttcaccgactggtccctgctggacgtactgcgccag accgaaggcgcgccgaccctggaccgcgtcgacgtggtccagcccgcgtccttcgccgtc atggtctccctggccgcgctgtggtccgcccacggcatcacccccgacgccgtgatcggc cactcgcagggcgagatcgccgcggccgccgtcgccggggcgctgtccctggaggacgcg gcccgcgtcgtcgcgctgcgcagccaggccatcgcccgcggcctcgccgggtccggcggc atgatgtcggtcccgctgcccgccgccgaggtcgaacagcgcctcgccgcgtacgagcac ctgtccatcgccgccgtcaacggcccccgctccaccgtcgtctccggcgccaccgcgccg ctggacgcgctccaggccgaactggtcggcgcggacatccgcgcccggcgcatcgccgtg gactacgcctcgcactccgcgcaggtcgagatggtgcgcgacgagctgcacaccgtcctc gcgccggtccgcccgcgcccggccgaggtgcccttcttctccaccgtcaccggcgactgg ctcgacaccaccgccatggacggcgactactggtacaccaacctgcgccagaccgtccgc ttccagcacggcatcggtgaactcctcgcccagggccaccgcttcttcatcgaggtcagc tcccacccggtgctgtccatcggcgtccaggagaccgtcgaggaagccggcggcacggcc gcggtgctcggcacgctccggcgcgacaccggcggtgtcgaccgcttcctgacctcgctc gccgaggctttcgtacggggcgccggcgccgactgggccgccgtcctcgcggacaccggc gcccgccgcgtcccgctgcccacctacgccttccagcgtgaacacctgtgggcgatcccc gaacggaccggggccagggccgaaacggatcccgcggacgcggagttctggacggcggtc gagcaggaggacgtcgatgccctcgcctccagcctgcgtctcgaccaggccgccctggcc ccggttctccccgccctctcgcactggcgcaagcaccgccgcgacctgtccaccgtggac tcctggcgctaccacgccacctggaagccgctgaccagcctgcccacggccaccctgacc ggcagctggctcgtcgtcgcccccgaagggaccgacaccgacggcctcaccgccgtcctc gccgcccacggcgccgagccgcgcaccctcgtcctggacgatgcctgcgccgaccgcgcg gtcctggccgagcgcctgaccggcctcggcgatctgacaggtgtggtgtcgctgctggcc gaggcagaggggcggagtgcggcgcaccccgcgctcagccggggcatcgccctgaccctc gcgctcgtccaggcactcggcgacgccgggatcgacgcacccctgtggtgcctgacccgc agcgccgtctccaccggccgtgccgaccggctgacccgccccgaacaggcccagatcctc ggcctcggctggaccgccgccctcgaacacccgcagcgctggggcggcctggtcgacctg cccgaacagctcgaccagcgggccggggagcgcctggccgccgtcctgaccggccgtacg ggtgaggaccagctcgccctgcgcgcctcgggcgtcctcgcccgccgcgtcgtacgcgcc acccccgcggacgccacccccgcccggccctggacgccgcgcggcaccaccctcgtcacc ggcggcaccggcaccctcgccccgcacctggcccgctggctcgccgggcagggcgccgaa cacgtcgtcctcaccagccgccgcggcccggacgcacccggcatggacgaactcgtccag gaactcgccgagctgggctgcgaggccggtgtcgtcgcctgcgacctgaccgaccgcgac gcggtcgcgcggatgctcgacggcctggcggccgagggccgtaccgtacgcaccgtcgtg cacaccgccgtcaccatcgagctggcgacgctggaggagaccacccacgaggcgttcgcg aaggtcatggacgccaaggtcaccggcgcccggcacctggacgaactgctcggcgacgac ctcgacgccttcgtgctctactcgtccaccgccggtatgtggggcagcggcgcgcacgcc gcctacgtcgcaggcaacgcctacctgaacgccctggcggagcaccgccgcgcccgcggc gcccacgccaccgccgtctcctggggcatctgggccgacgacctcaagctcggccgcgtc gaccccacccagatccgccgcagcggactggtcttcatggacccgcagctggccctcacc ggcctgcggcaggccctggacggcgacgagacggtgctggccgtcgcggacgtggactgg gagcgctaccaccccgtcttcaccgccgcccggcccacccggctcttcgaggacgtgccc gaggtccagcggctcgaagaggacaccaccgagaccgcggacaccggcagcgagttcgcc acccggctcctcgggctggcccccgtcgagcaggaccggctgctgctggacctggtgcgc accgaggcggccaccgcgctcggccacgcctcacccgacgtgctctccgaacagcgcgcc ttccgcgatgtcggcttcgactcgctgaccgccgtcgacctgcgcaaccggatcgccagc gtgaccgggctcgccctgccgagcaccatggtcttcgactaccccaacccgctcgcgctc gtcgccttcctgcgcgagtcgctggccgggtccgccaccggcaccaccgccacggccacc ggcaccaccgccgccgacgacgagcccatcgccatcatcggcatgagctgccgctacccc ggcggcatcggctcgccggaggacctgtggcgcctggtcgccgagggcggcgacgccacc ggcgagttccccaccaaccgcggctgggacgcggagggcctgtacgaccccgaccccgac cgggccgggcacacctactcgacccggggcggcttcctccacgaggccaccgacttcgac gcctccttcttcggcatctcgccccgtgaggccctggccatggacccccagcagcgcctg ctgctggagacctcctgggaggccatggagcgcgccgggatcgaccccgcggccctgcgc ggcagcagcaccggtacgttcatcggcgccagctaccaggactacggcgccggcgccggc agcccggagaacgccgaggggcacctgatcaccggcaccatctccagcgtcctgtccggc cgcctctcctacacctacggcttcgagggcccggccgtctccctggacaccgcctgctcc tcctccctggtcgcgctgcacctggcctgccagtcgctgcgcaacggcgagagctccctg gctctcgcgggcggcgtcagcatcatgtccacgcccggcgccttcgtcggcttcagccgg cagcgcgcgatggccgccgacggccgctgcaaggcgtactccgaccaggccgacggcatg agcctggccgaaggcgtcggcctggtcctcgtcgaacggctctccgacgcccgccgcaac ggacaccaggtcctcgccgtcatccggggctccgccgtcaaccaggacggcgcctccaac ggcctgaccgcgcccaacggcccgtcccagcagcgcgtcatccggcaggccctggccaac gccaaggtggacccggacggcatcgacgtggtggacggccacggcaccggcaccgccctc ggcgaccccatcgaggcgcaggccctgctcgccacctacggccagggccgcgaccccgag cggccgctgctcctgggctccgtcaagtccaacatcgggcacacccagatggcgtccggc gtggccagcgtcatcaagatggtcatggccatgcgccacggcgccgtgccgcgcagcctg cacatcgaccggccgtcctcgcacgtggactggagctccggcgccatccgcctgctcacc gagccgctcgactggccgagcaccggccacccgcgccgcgcgggcgtctcctccttcggg ctcagcggcaccaacgtccacaccatcctcgaacaggccccgcaggagccggccgaggac gccaccgacgccgcgccggtgcgcccggccgagcccgctcccgtaccgctggtcctgtcc ggacgcaccgaggagggcctgcgcgcccaggccggacggctgctgtcgcacctcgccgac caccccggcctgccgctcaccgacctcgcgttctccctcgccacctcccgctccgccctg gagcaccgcgcggccgtcgtcaccgacgaccccgacgccctcacccgggcgctgaccgcg ctgcgcgacgcggacgccgacggcgcgctgctcaccggcagcccggaccgcggccggctg gccttcctcttcaccggccagggcagccagcgccccggcatgggacgcgagctctacgac acccaccccgtctacgcccaggccctggacgccgtactggcccgcttcgacctcgaactc gaccgcccgctgcgggacatcctgttcgcggagccgggcacgcccgaggccgagctgctg gacgacaccggctacacccagcccgccctgttcgccctcgaagtggccctgttccgcctc gccgagtcctggggcctgcgccccgactacgtcgcgggccactccatcggcgagttcgcc gccgcgcacgccgccggggtcctctccctggaggacgcctgcactctcgtcgcggcccgc ggccgcctgatggcggccctgcccccgggcggcgccatggcgtccgtcgaggccaccgag gacgaggtggccgccgtgctcaccgcgtacgagggacgggccgcgatcgccgccgtcaac accccgggctcgctgaccgtctcgggcgacgaggacgcggtcctcgccgtggcggcgcac ttcaaggagctcggccgccgtaccaagcggctgcgcgtcagccacgccttccactcgccg cacatggacccgatgctcgcggacttcgcccgcgccgtcggctccgtcacctgccacgcg cccaccgtgccgctggtgtccaccgtcaccggcgccctcctcacccacgaggaactggcc gcgccggagtactggaccgggcaggtccgcggcacggtccgcttcgccgacgccgtacgg cacctcaccgaacacggcgtgacgaccttcttcgagctgggtcccgacgccgtactcagc ggcgcggtgcgcgaaggcaccggtgagcaggaccgggccaccgccgtaccggcgctgcgc cgcgaccggccagaggccccggcgctcaccacggcgctggcccggctccacctccacggg gtgcgggtcgactgggaggccgtgttcgcgggcagcggtgcccgccggatcgacctgccc acctaccccttccagcgcgagcgcttctggcccgagccgaccgccgggacggccgcaccc gcacagcccgccgacgaggcggacgcggagttctggtcggccgtggagcgcgcggacctc gcgtccctcggctcctcgctggacctggacgacgacaccctcaccgccgtcgtacccgcc ctctcctcctggcggcgcaagagccgggagcgctccaccgtcgacggctggcgctaccgg accacctggaaggccctcaccggcccggccgccggcggacgcccgtccggcacctggctg gtgctcgtgccggccgccggggcgggggagtgggccgaggcggtcatcggcgccctgggc accgatgccgtacgtatcgacatcgccgcaccgcagcgccaggagctggcccagcggatg cgcgaactgtccgccgaacacggcgggttcgcgggtgtcctggccctgccggcaacagcc ggcgaaggcgacgcggaccccgcgaccgagggcctgctgctgacggcgaccgccgtccag gccctgggagacgccggaatcgatgcgccgctgtggtgcgtgacccgcaccgccgtggcc gtcgaccgcgccgaacacccggcccgccccgcccaggccgccgtctggggcctgggcagg gtggccgcgctggagcacccgcagcgctggggcggtctcatcgacctcccggacgagctc gacagcaccaccctgcgccgtctggccaccgtcctcgccgacagcggcggcgaggaccag ctcgccgtacgcaccaccgcggccttcgcccgccgcctggcgcaccaccgcgtcatgccg gactccgaggcgggtacgttcagccccaccggcaccgtgctcgtcaccggcggcaccggc gctctcggcggacatgttgcccgctggctcgccgaagcgggcgcgcagcacctgctgctg gtcagccgccgcggcgccgacgcgcccggcgcgggcgaactggccgcgcagatcgaggac atgggcgtacgggtcaccctcgcggcgtgcgacaccgccgaccgcggcgcgctcgacgcc gtactggccgagatccccgaagagcacccgctcaccgcggtcttccacaccgccgggacc gtcgacgacggcaccctggacacgctcacccccgagcagttcacctccgtcctgcacgcc aaggtcaccgcgacccgcaccctgcacgaggccacccgcgacctggacctgagcgccttc gtgctcttctcctccgtcgccggcaccctcggcgcacccggccagggcaactacgccgcg gccaacgccttcctcgacgccttcgccgagcaccgccgcgcccacggcctgcccgcgacc tcgatcgcctggggtccctgggccgaggacggcatggcggccgacggcaccgacgtccag gcacgcatccggcgaggcggctacaacccgctgccgccgcagctcgccctcaccgccctg cggcaggcgatcgagcagggcgccccgacgctcaccctcgcggacatcgactggcagcgc tacgcggaggtgttcaccgcgacgcgccccagccccctcgtcggcgacctgcccgaactg cgccaggccaccgcacccgccgggacagcggaggccgccctgcgggaaccggccctgcgg cagcggctcgccgggctctcgccggccgcgcgcccgcgcttcgtgctggatctcgtacgg acccgggtcgccgcggtcctcggccacagcggcacctcgggcatcggcgccgaccgcgcc ttcagcgacctcggtttcgactcgctgaccaccgtcgaactgcgcaacaccctcacggcc gccaccggcctgaaactgcccgcgaccctcgtctacgactacccgacaccgatcgccctc gccgacttcctgctcgccgaactccagggcgccctgcccgagtccgaccggctcgccccg gcccccggaggccgcgccgccgacgacgacccgatcgccgtcgtcggcctgaactgccgc ttccccggcggcatccggtcccccgaagacctctggcagctgctcggccggggcgaggac gccatctccggcttccccgcggaccgcggctgggacctggacgccctcgcccagggcggc tccgcgaccctcgaaggcggattcctcgacggcgtcggcctcttcgacgccgcgttcttc ggcatctcgccccgcgaggccctggccatggacccccagcagcgcctgctgctggagacg tcctgggaggtcttcgagcgggccggcatcgacccggccaccctgcgcggcagccgtacc ggcgtcttcgtcggcaccaacggccaggactacgccacggtcctgcgccgggcgaccggc accgccgacatccgcgggcacgtcgccaccggcaacaccgccagcgtcctgtccggccgc ctctcctacgccttcggcctggagggcccggccgtcaccgtcgacaccgcctgctcctcc gcgctggtcgccctgcacatggcggcgaacgccctgcgcagcggcgagtgcaccctcgca ctggccggtggcgtctcggtgatgtcgagccccgactccttcaccgagttcacggtgcag ggcgggctcgcccccgacggccgctgcaagcccttcgccgacgcggccgacggcaccagc tggtccgagggcgtgggcgtcctcgtcctggaacggctctccgacgcccggcgcaacggc cacgaggtgtggggcatcgtgcgcggcaccgccgtcaaccaggacggcgcctccaacggg ctgaccgcgcccagcggacgggcccagcagcgcgccatccgccaggccctcgccgatgcc gacctcgcccccgccgacatcgatgtggtcgaggcgcacggcaccggcaccaccctcggc gaccccatcgaggcgcaggccctcatcaccgcctacgggccggaccgcgagcgcccgctg ctgctcggcgccgtcaagtcgaacctgggccacacccaggccgccgcgggcgtcgcgggc accatcaagatgctcctggccatgcgccacggcgtgctgcccaagaccctgcacgtcgac gccccgtcctcgcacgtcgactggtcggacggcacggtctcgctcgtcaccgaggagcag gcgtggcccgagaccggccacgcccggcgggccggcgtctccgccttcggcgtgagcggc accaacgcccacgtcatcatcgagcaggcaccggaggcggaggagcccgaggcggacggg cccgccgagcccaccacggtgccgggcctcgtgccctggccggtgtcggccaagtccgag gccgcgctggcggcacagatcgagcggatcacggcgctgaccggcctcgcgcccgccgac gtgggccactccctggccaccggcaggtcggcgttcacccaccgcgcggtcctcgcggcc gacggtacgggcgtacgggaactcgcccgcggcatcgcccaggagaccgacggcaagctg gccctgctgttctcgggccagggcgcgcagcgcgccgggatgggccgcgagctgtacggc cggttcccggtgttcgccgaggcgctggacgcggtactggcgcacttcgacgccgggctg cgggacgtgatcttcggtgacgcggagggcctggacgagaccgggttcacccagccggcc ctgttcgccatcgaggtggcgctgttccggctggccgagtcgctgggtatacgcccggac ttcgtggccggccactcgatcggcgagatcgcggcggcgcatgtggcaggagtgttctca ctggcggacgcgtgtgcgctggtggcggcccgtgcccggctgatgcaggcgctgccggag ggcggcgcgatggtggcgatcgaggccaccgagggcgaggtcgggccgcggctggccgac ggggtgtcgatcgcggcgctcaacggcccggagtcggtggtgatctccggaacgcaggac gcggtcctgcggatcgcggcggaattcgccgacgagggccgcaagacccggcgcctgtcg gtgagccacgccttccactcgccgctgatggacccgatgctggcggacttccggcaggtg gccgaggggctggcgtacgaggccccgcgtatcccgctcgtgtccaacgtgacgggcgaa ctcgccaccgcggagctgatctgcacgcccgggtactgggtgcagcacgtacgggacacg gtgcggttcgccgacggtgtccgcgcgctggaggccgagggcgcctcggtcttcctggag gtgggcccggacggggtgctgacggcgatggcccagcacagcctggccgacgcggccgtg gccgtccccgccctccgcaaggaccgccccgaggaaaccgccctgctcaccgcgctggcg cagctgtacgtcaccggggtcggcatcgactggtccggcgtcttcgacggcaccggcgcc cgccgcgtggacctgcccacctaccccttccagcaggagtggttctggccggagaccgcg cccgcggcgagcccggcggacggctcgcaggctccggtggacgccgagttctgggacgcg gtggagcgcgaggacctgacagcgctctccgccgacctcgacctggacggctccgcgctg ggcgccctcgtacccgccctgtccgcctggcgccgcaagcgcgtcgagcgctcgaccgtc gacggctggcgctaccaggtgacgtggaagccgctcaccggcacctcggcgagcacgctt tccgggccgtggctggcgctcgtcccggcaggcggtgccgatgatgagtggaccgcctcc gtggtcgcggccctcggcgacgacgccgtgagcgtcgaggccgacccggccgactcccgg gcgctgaccgcccggctggccgaactggccgcgcagggccaggagttcgcgggagtcgtc tcgctcctggccgcccggaccggcgaaggtgtcgcctccggcggggcggcctggccggac gcggcggtacaggcactggccgacgccggtatcggtgcccgcctctggtacgtcacccgt ggcgcggtggcggtcggccgctcggagacggacgtggacgccgcccaggcggcggtgtgg ggagcgggccgggtcgcggccctcgaccaccccgacctctggggcggactcgtcgacatc gcggacgtcctcgaccggcgctcggcggaccggttccgtgccgtgctgtccggtacgggc ggcgaggaccaggtggcactgcggtcctcgggcgccttcggacgccggctggtacgcgcc acggccgacaccccgtcgactccgtggcagccgtccggcacggtcctggtcgtcggcggc gcgtccggcaccggcgggctctgcgcccgctggctcgccggacagggcgcccagcacatc ctgctggccgggcccgccacgcccgaggcggacaccctgcctgccgaactcgacggcctc ggcgctgagctgacgcgggtcacctgcgacccggccgacagcgacgcactgctgaacgcc ctcaccgcactcccgcccacggcaccgctgaccgccgtcgtctacgccgacgcggaagca ctgtccggcgacggcgagccgggcacagccctggccgcgctgcacacggccgtggagaac ctggcggccgtcgccgaagcggcggccggcgaacggcccctggacgccttcgtcctgtgc tcctcgatcgccggtacctggggtgccggcggccggggcgcggaggcggcggccggagcc ctgctggacgccctggcccggcggtaccgcgcacgcggactgcgtgccctgtccgttgcc tggggcgcctgggcggacaccaccgacgacagcctggccgcgcatctgcgggtcaacggc ctgccggtgatggacgccgaacgggccctgtccgcgctctcccgctccgccggtaccgac gcggcctcggtgacggtcgccgacgtacggtgggaccggttcgcgccggccttcacccgc aaccggcgcggcgccctgttcaccgacctgcccgaggccagggccgcactcgcggaaccc gggaacgccgggcagggcaccgcgaccggactcggggcccggctcgccggccgaccggcc gccgagcagaccgaggcgctgctgaccctgatccgcggcgaggtggccacggtgctcggc ttcgccgacgccgacgccgtcccgtccggacccgccttcaaggacctcggcttcgactcg ctgaccgccgtcgacctgcgcaaccagctcgccacggcgaccggcctgtccctgcccgcc accctcgtcttcgactacccgacggcggaggcgctggccgggcacctgcggaccgagctc ttcggcgaggacggcgacgcgctgcccgccgtcggagcggtacgggcgcggggcgcggcc gacgacccggtcgtcatcgtcggcatgagctgccgctacccgggcggggtccgctcgccc gaggacctgtggcagctggccatgggcgaggtggacgccatcggcggcttccccgtggac cgtggctgggacctggagacgctgctgaacggcgaccgggacggccgcggccggaccgcc gtccgcgaaggcggcttcctctacgacgtggccgacttcgaccccgggttcttcgggatc gcgccgcgcgaggccatggtgatggacccgcagcagcgcatcctgctggaagcatcctgg gaggcgctggagcgggcgggcatcgacccggccgggctgcgcggcggtgacaccggcgtg ttcatcggcggcggctcgggcgactaccggcccgaggcgggccagctgggccacgcccag accgcgcagtcggccagcctgctgtccggccgggtggcctaccacttcggcctggaaggc ccgaccgtcagcgtcgacacggcctgctcgtcgtccctggtggcgctccacctggccgcc caggcgctgcgcaacggcgagtgctccgtcgcgctcaccggcggtgtgacggtgatgtcc agcccggtgaacttcgtcgagttcggcgagatgggcgccctcgcgcccgacggccgctgc cgggccttcgccgactccgcgagcggcaccggctggtccgagggtgtgggcgtcctcgta ctggagcgcctctcggacgcccgccgcaacggccacgagatcctggccgtactgcgcggc tcggcgatcaaccaggacggcgccagcaacggcatcaccgcgcccaacggcccctcgcag cgccgtgtcatccgccgggccctggccgacgccgggcttgcgccgggcgacgtggacgcg gtggaggcgcacggcaccggcaccaccctgggcgaccccatcgaggcgcaggcgctgctg gccacgtacgggcaggagcgtgaactgccgctgtacctcgggtcgttgaagtccaacatc ggccacacccaggccgccgccggtgttgccggcgtgatcaagatggtgcaggccatgcgg cacggcgtgctgcccaggaccctgcacgtcgacgcgccgtcggcgcacgtggactgggac tccggcgccgtcgagctgctgacggaggcggccgactggccgcgtacggaccacccccgg cgcgccggcatctcggccttcggcgccagcggcaccaactcccacgtgatcatcgagcag ttcgagcagcccgaaccggcggtcaccaccgaaccggtggaggcccacggcccgctgccg gtgcccgtgtcggccgccgcgccgcaggcactgcgggcccaggcccggcagctgcactcc tacgtgaccgcccggcccggactcggcaccgccgacctggcccgcgcgctggccaccacc cgctcggtcttcacccaccgcgccgccgtcctcgcgggcgaccgcgacgaactgctggcc ggcctggccgcgctcgccgacggccgcaccgcaccccaggtcgtacagggtgaggcggcg gcccgccgcggcaagctcgcggtgctgttctccggccagggcacccagcgcctgggcatg ggacgggagctgtacgcccgcttcccggcgttcgccgcggccttcgacgcggtgaccgcg cacctggacaccgaactggaccgccccctgcgggacgtgctgtccgaggacgcggagcgg ctgaacgagaccggctacacccagcccgcgctgttcgccatcgaggtggcgctgttccgc ctggtggagtcctggggtatccgcccggacttcgccgccgggcactcgatcggcgagatc gcggccgcgcacgtggccggggtcttctccctggaggacgcctgcaaggtcgtggccgcg cgggcccggctgatgaacgccctgccgtccggcggcgccatggtcgccgtccaggccacc gaggaggaggtgacggccctgctgaccgcgggagtgtcgatcgccgcggtcaacgggccg cggtcggtggtcctctccggcgacgagggcgccgtcctggacatcgcggacaaactcacc gccgacgggcgcaagactaggcgtttgcgggtcagccatgcatttcactcactgcacatg gacgccatcctcgacgacttccggcgggtcacccgcagcgtggactaccacgccccgcgg atcccgctggtgtccaacgtcaccggcgaggcggccaccgaggagcaggtgtgctccccg gactactgggtgcgccacgtccgcgaggccgtccgcttcggcgacggcatccgcaccctc gccgagagcggcgtgaccgccttcctggagctcggccccgacggcgggctgtgcgccatg gcccaggacaccctggacgccctggcgtcgcgggccctggccgtaccggtcctgcgcaag gaccgcggcgagcaggaatccgcggtcaccgccctcgcccggctgtacgccgacggagcg gccccggactgggacgccctgctcgccgggacggccaccgggccccgccgcaacgacctg cccacctaccccttccagcgccagcgctactggcccgccaccctgccgggcgacgcttcc gcagcgccggagggcgcggacgacggcttctggacggcggtgcgcgaggccgacttcgcc tcgctggagacgacgctgaacgtcgacggcgaagcgctggccaaggtgctccccgccctc gccgactggcgccgccggcgcggcgaggagaacaccgtcgacggctggcggcagcagatc acctggcagccgctgagtccgcagcccgcccgcaccccggcaggcacctggctcgccgtg ctcccggccggacacgccgacgacccctgggccgccgacgccgtcaccgcgctgggaccg gacaccgtacgcctggaagtggcggaccccgaccgagcggcgctcgccgaacggctgcgc gcactggccgccgacgggttcgcgttcaccggagtggtgtccctgctggccctcgccacc acgcccgcgcccggcgcggacgcccccgaggcactggccctgaccaccgccctgatccag gcgctcggcgacgcggacctcgccgcacccctgtggtgcgtcacccgcggcgcggtcgcc gccgcgccctccgagccggtacccgggctcgcccaggccgccgtctggggcctgggacgg gtcgccgcgctggagcacccgcagcgctggggcggcatggtcgacctgcccgacaccctc gacgagcggtccacggcccgcttcgccgacatcctcgcggcccccggaggcgaggaccag atcgcggtccggccctccgccgccctcggccgccggctggtccccgtaccggccggacgc ggcacggcggagtgggaccccaccggcaccgttctgatcaccggcggtaccggggccctg ggcgcccacgtggcacgccgtctcgccgaggcgggcgcccggcacctgctgctcctcagc cgccggggcccggacgcgcccggagccggcgagctgcggaccgaactcactgccctgggc gccgaggtcaccctcaccgcctgtgacgccgccgaccgcgacgcgctcgcggcagtcctg gcggacatccccgaggaagcgccgctgaccggcgtgatccacacggcgggcgtcctggac gacggtgtcctcgacagcctcacccccgaccgctacgaggccgtcttccacgccaaggcc gcctcggccctggccctgcacgacctcacccgcgaccgggacctggccgtcttcgccttg ttctcctcgtcctccggcgcggtcggcaacgccggccaggccaactacgccgccgccaac gccttcctggacgcgctcgccgaacagcgccgcgcccagggcctggccgccacctcgatc gcctggggcgtgtggggcggcgacgggatggccgccgaccagcgggcggcggacgtggcc cggcgtaccggcatccgcccgctcgacccggacctcgccgtcgtggcgctgcgccgggcc gtgctggacgggcggcccaccgaggtcgtcgccgacatcgaacgcgaccggttcgtccgc tccttcaccgccgtacggcccagtccgctcctcggtgagccggccgcggccggacacccg gcggcggacggcgcgggcgaggacgccaccggcgacgcgctgcgcgagaagctggcgggc ctttcgcccgccaagcgctccgaagccgtactggacctggtgcgcacccgggccgcggcc gtactcggccaccccacggccgacgcggtgggcgccgaccgggcgttccgcgacctcggc ttcgactccctgagcgccgtcgaactgcgcaaccagctcggcgccgcgaccggactgagc ctggccgccacgctcgtcttcgaccaccccagccccgccggcctggcggcccacctcctg ggccggctcgtccccgaagcggggacgggggaggggaccggcgacggcgacccggacgcg gccggcatcagggccctgctcgcctccgtatcgctgcaccagctgcgggagatcggcgta ctggagcccctgatgaagctcgccgccgaacagaccgcggcagccggcggccaggccgcc ggagcgccggagaccgacgcctacgaggagtcgatcgacgcgatggacgtcgccgacctg gtgcaggcggcacttgacggcaatgcccccgaagagcgctga

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