Streptomyces rochei: SRO_0885
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Entry
SRO_0885 CDS
T06265
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
srj
Streptomyces rochei
Pathway
srj00270
Cysteine and methionine metabolism
srj00480
Glutathione metabolism
srj01100
Metabolic pathways
srj01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
srj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SRO_0885
09106 Metabolism of other amino acids
00480 Glutathione metabolism
SRO_0885
Enzymes [BR:
srj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
SRO_0885
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Gene cluster
GFIT
Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
BBC92061
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Position
950933..952267
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AA seq
444 aa
AA seq
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MSDVMDEGGDCTGHRATVTEAEVDALVQGICFKTGPPRTLGVELEWLIHDRDLPQRPVTP
ERLRAAYAAVRAVPLGSALTVEPGGQLELSSPPAASLMECVGTVSADLAAVRAVLDEQGL
VLVGLGHDPFRVPERFLREPRYDAMETCLDRTGPAGRHMMRASASVQVCVDAGHEEPGPL
GHGRRWWLAHQLGAVLVAAFANSPLIDRLPTGWLSSRQLMWAKIGAARAGAPPPREEPRS
AWARHVLDSPVMCVRRDGGPWEVPEGLTFREWTRGQGSRPPTRADLDYHLTTLFPPVRPR
GHLELRMIDAQPGEDGWIVPLAVTAALFDDPQAAETAYRCVKPLAERALNLPAPHNPLWS
DAARLGLADPELREVAAACFAAALDALPRLGAGTEVTGAVAGYLERYVARGRCPADDLLD
ALPGTPTAPAGSGPAAQGRKDVPS
NT seq
1335 nt
NT seq
+upstream
nt +downstream
nt
atgtccgatgtgatggacgagggtggcgactgtacggggcaccgtgcgaccgtcaccgag
gccgaggtggacgccctggtccagggcatctgcttcaagaccgggccgccccggaccctc
ggtgtggagctggagtggctcatccatgaccgggacctgccgcagcgtcccgtgacaccc
gaacgactgcgcgcggcctacgcggccgtgcgtgccgtacccctcggttcggcgctcacc
gtcgaacccggcggccagctggagctcagctcgccgcccgccgcctccctgatggagtgc
gtcggcaccgtctccgccgacctcgcggccgtccgcgccgtcctcgacgagcaggggctc
gtcctcgtcggtctcgggcacgatcccttccgcgtcccggagcggttcctgcgcgagccg
cgctacgacgcgatggagacctgcctggaccgcaccggaccggccgggcggcacatgatg
cgtgcctccgcctccgtgcaggtctgcgtggacgcgggccacgaggagccgggcccgctg
gggcacgggcggcgctggtggctggcgcatcagctgggcgcggtcctggtggccgcgttc
gccaactccccgctgatcgaccggctgcccaccggctggctgtccagccggcagctgatg
tgggcaaagatcggcgcggcccgggcgggcgcgcccccgccgcgcgaggagccgcggtcc
gcgtgggcccggcatgtactggactccccggtgatgtgcgtacgccgagacggcgggccc
tgggaggtccccgaggggctgaccttccgggagtggacacgggggcaggggtcccggccg
cccacccgggcggacctcgactaccacctgaccaccctgttcccgccggtcagaccgcgt
ggccatctggagctgcggatgatcgacgcacagccgggcgaggacggctggatcgtgccg
ctcgcggtgacggcggcgctcttcgacgatccgcaggccgccgagaccgcctaccgctgt
gtgaagcccctggccgagcgggccctgaacctgccggccccgcacaatccgctgtggagc
gacgcggcccggctcgggctcgccgacccggagctgcgggaggtggccgccgcctgtttc
gcggcggcgctcgacgcgctgccccggctcggtgccggcaccgaggtgacgggcgccgtc
gcggggtacctggagcgctatgtcgcccggggccgctgcccggccgacgatctgctggac
gcgctgcccggcacccctaccgccccggccgggagcggccccgccgcccagggcaggaag
gacgttccctcatga
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