Streptomyces rectiverticillatus: FGW37_23510
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Entry
FGW37_23510 CDS
T06927
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
srk
Streptomyces rectiverticillatus
Pathway
srk00470
D-Amino acid metabolism
srk00550
Peptidoglycan biosynthesis
srk01100
Metabolic pathways
srk01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
srk00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
FGW37_23510
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FGW37_23510
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FGW37_23510
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
srk01011
]
FGW37_23510
Enzymes [BR:
srk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
FGW37_23510
Peptidoglycan biosynthesis and degradation proteins [BR:
srk01011
]
Precursor biosynthesis
Amino acid ligase
FGW37_23510
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
QLE74156
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Position
5286108..5287256
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AA seq
382 aa
AA seq
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MSSEITPQSPGRKPRVAVVFGGRSSEHAISVVTAGAVLRAIDRTKYDVLPIGITTDGRWA
LTADDPERMAIADRALPSVAQLAQSPDGSVVLPVDPSDRELVYTEPGTMPKALGEVDVVF
PVLHGPYGEDGTLQGMLELSGIPYVGAGVLASAVGQDKEYMKRVFVSFGLPVGPYEVVRP
REWDTDPAAARKKIVDFAGEHGWPVFIKPARAGSSMGITKVDDVSGLDEAVAEARRHDPK
ILVESLLRGREIECGVLEFEDGPRASVPAEIPPVTAHDFYDFEAKYIDSATGLVPAPLTP
QETAKVQELAVQAFDAASCEGLVRADFFLTEDGEFVINEINTLPGFTPISMYPRMWQESG
VGYTELIDRLIQAALRRPTGLR
NT seq
1149 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagatcaccccccagagccctggccggaagccgcgtgtggcggtcgtcttc
ggcggccgcagttccgagcacgccatttccgtggtcaccgccggcgccgtgctgcgcgcc
atcgaccgcacgaagtacgacgtgctgccgatcggcatcaccacggacggccgttgggcc
ctcaccgccgacgaccccgagcggatggccatcgccgaccgcgcgctgccgagcgtcgcg
cagctcgcccagtcgcccgacggctccgtcgtcctgccggtcgacccctccgaccgcgag
ctcgtctacacggagccgggcacgatgcccaaggcgctgggcgaggtcgacgtggtcttc
cccgtcctgcacggcccctacggggaggacggcaccctccagggcatgctggagctctcc
ggcatcccctacgtgggcgccggagtgctcgcctcggccgtcggccaggacaaggagtac
atgaagcgcgtcttcgtctccttcggcctgcccgtcggcccgtacgaggtcgtccgcccc
cgcgagtgggacaccgacccggccgccgcccggaagaagatcgtcgacttcgccggcgag
cacggctggcccgtcttcatcaagcccgcccgcgccggctcctccatgggcatcaccaag
gtcgacgacgtctccggcctggacgaggccgtggccgaggcgcgccgccacgacccgaag
atcctggtcgagtcgctgctgcggggccgggagatcgagtgcggcgtcctggagttcgag
gacgggccgcgcgccagcgtccccgccgagatccccccggtcaccgcccacgacttctac
gacttcgaggcgaagtacatcgactccgccaccggtctcgtccccgcgccgctgacgccg
caggagacggcgaaggtgcaggagctcgccgtgcaggccttcgacgccgcctcgtgcgag
ggcctcgtgcgcgcggacttcttcctcaccgaggacggcgagttcgtcatcaacgagatc
aacaccctgccgggcttcacgccgatctccatgtacccccgcatgtggcaggagagcggc
gtcggctacaccgagctgatcgaccgcctcatccaggcggcgctgcgccggcccacgggc
ctgcgctag
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