Streptosporangium roseum: Sros_6420
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Entry
Sros_6420 CDS
T01137
Name
(GenBank) 2-oxoisovalerate dehydrogenase
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
sro
Streptosporangium roseum
Pathway
sro00280
Valine, leucine and isoleucine degradation
sro00640
Propanoate metabolism
sro00785
Lipoic acid metabolism
sro01100
Metabolic pathways
sro01110
Biosynthesis of secondary metabolites
sro01210
2-Oxocarboxylic acid metabolism
Module
sro_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Sros_6420
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Sros_6420
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Sros_6420
Enzymes [BR:
sro01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Sros_6420
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Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
DUF6457
Motif
Other DBs
NCBI-ProteinID:
ACZ89134
UniProt:
D2B0C8
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All DBs
Position
7029220..7031430
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AA seq
736 aa
AA seq
DB search
MARDTVETHFTEAVTALSPGAPRDPGMPVREGTTLTGARCRELFEFQLGSRLLDVASRWL
REHGEGFYTIGSAGHEGNVAVAAAVRVTDPALLHYRSGAFYLARSVMAGRLPEEGLRDVL
LGLTASAEEPMAGGRHKVFGHPDLAVIPQTSTIASHLPRAVGVAFAIERARQLGLAGAWP
GDAIAVCGFGDASVNHASALSGLNTAAYGSYQGLAMPVLFVCEDNGLGISVRTPDGWVEA
ARHRLLEYFEADGCDLADVHDVARAAAEHVRRHRSPALLHISTVRLMGHAGSDVELSYRT
KREINADLERDPLVATARLLVEAGLTTPDELLTRYETTREHLFKMAMESSRRSRLTSAVE
IMEPLAPRTPEAVAPASTVAAASRERAFGGRLPELEGPLTLSQAINRTLADTLAAHPDVL
VFGEDVARKGGVYGVTRGLQKRFGAGRVFDTLLDEQAVLGLALGSGVSGLLPVPEIQYLA
YLHNALDQIRGEAATLSFFSRGAFRNPMVVRVASYAYQKGFGGHFHNDNSVAALRDIPGL
VVASPARPDDAASMLRTCLAAARTDGSVCVFLEPIALYNTRDLFDDGDNGWLSPYAPPAR
WAETHVPIGRARSYGDGRDLTIVTFGNGVRMSLRAAVRLTAEGYSCRVLDLRWLSPLPID
DLLHAAELTGRVLIADETRRTGGVSESIVAELLDAGFTGRIARVTSADSFIPLGDASSHV
LLSEGEIEAAARKLLG
NT seq
2211 nt
NT seq
+upstream
nt +downstream
nt
gtggcgcgcgacactgttgagactcatttcaccgaggcggtgaccgccctctcccccggg
gccccgcgtgatcccggcatgcccgtgcgggaggggacgaccctgaccggcgcccgatgc
cgcgagctgttcgagttccagctcggcagcaggctcctggacgtcgcctcgcgctggctg
cgcgagcacggcgagggtttctacaccatcggctcggccgggcacgagggcaacgtcgcg
gtggcggcggcggtccgggtcaccgaccccgccctgctgcactaccgctcgggggccttc
tacctggcccggtccgtgatggcggggcgcctgcccgaggaggggctgcgcgacgtcctg
ctgggcctgaccgcctcggcggaggagccgatggcgggcggccgccacaaggtcttcggc
caccccgacctggcggtgatcccgcagacctccacgatcgccagccacctgccgcgcgcg
gtgggcgtggccttcgccatcgagcgcgcccggcagctcggcctggcgggcgcgtggccc
ggcgacgcgatcgcggtgtgcggcttcggcgacgcctccgtcaaccacgccagcgccctg
tccgggctcaacaccgccgcctacggctcctaccaggggctggccatgccggtgctgttc
gtctgcgaggacaacggcctgggcatcagcgtgcggaccccggacggctgggtggaggcc
gcccgccaccggctgctggaatacttcgaggccgacggctgcgacctggccgacgtccac
gacgtggcgagggccgccgccgagcacgtccgcaggcaccgctcccccgccctgctgcac
atcagcaccgtccggctgatgggccacgccggctccgacgtggagctgtcctaccggacc
aagcgggagatcaacgccgacctggagcgcgacccgctcgtcgccaccgcccgcctgctc
gtcgaggcgggcctgaccacgcccgacgagctgctgacccgctacgagacgacgcgcgag
cacctgttcaagatggccatggagagctcccggcgctcccggctgacctcggcggtcgag
atcatggagcccctcgccccccgcacccccgaggccgtcgccccggccagcacggtggcc
gcggcttcgagggagagggccttcggcggcaggctgcccgagctggagggcccgctgacc
ctctcccaggcgatcaaccggaccctggccgacaccctggccgcccaccccgacgtgctg
gtcttcggcgaggacgtggcccgcaagggcggcgtctacggcgtcacccgcggcctgcag
aaacgcttcggcgcgggccgggtgttcgacacgctcctcgacgagcaggccgtgctcggc
ctggcactggggtcgggcgtctccgggctgctgccggtgcccgagatccagtatctggcc
tacctgcacaacgcgctggaccagatccggggcgaggccgcgacgctttcgttcttctca
cgcggcgccttccgcaaccccatggtggtccgcgtcgcctcctacgcctaccagaagggc
ttcgggggccacttccacaacgacaactccgtcgccgcgctgcgcgacatccccggcctg
gtcgtcgcctctcccgcacgccccgacgacgcggcctcgatgctgcgcacctgcctggcc
gccgcccgcaccgacggcagcgtctgcgtcttcctcgaaccgatcgccctctacaacacc
cgcgacctgttcgacgacggcgacaacggctggctctcgccgtacgcgccgccggcccgc
tgggcggagacgcacgtcccgatcggccgcgcccgcagttacggcgacggccgcgacctg
accatcgtgaccttcggcaacggcgtgcggatgagcctgcgcgccgcggtcaggctcacc
gcggagggatacagctgccgggtgctggatctgcgctggctgtcgccgctcccgatcgac
gacctgctgcacgcggcggagctgaccggcagggtgctgatcgccgacgagacccgccgt
accggcggcgtctcggagagcatcgtcgccgagctgctcgacgccggtttcaccggcagg
atcgcccgggtgacctccgccgacagcttcatcccgctgggcgacgcctccagtcatgtg
ctgctgtcggagggcgagatcgaggccgccgcccgcaagctgctgggctga
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