Streptomyces roseicoloratus: RGF97_25575
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Entry
RGF97_25575 CDS
T09671
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sroc
Streptomyces roseicoloratus
Pathway
sroc00300
Lysine biosynthesis
sroc00550
Peptidoglycan biosynthesis
sroc01100
Metabolic pathways
sroc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sroc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RGF97_25575 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RGF97_25575 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RGF97_25575 (murF)
Enzymes [BR:
sroc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RGF97_25575 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DHHA1
Motif
Other DBs
NCBI-ProteinID:
WMX47511
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Position
5651396..5652826
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AA seq
476 aa
AA seq
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MIALSLAEIAEIVGGRPHDIPDPAVRITGPVVIDSREVKPGSLFAAFTGENVDGHDYATR
AVEAGAAAVLAARPVGVPAIVVEDVQTALGALARAVVGRLGTDVVALTGSAGKTSTKDLI
AQVLQRHAPTVWTPGSLNNEIGLPLTALTATAETRHLVLEMGARGIGHIRYLTGLTPPRI
GLVLNVGTAHVGEFGGREQIAQAKGELVEALPAAEEGGIAVLNADDPLVRAMASRTTARV
TLFGEADEAAVRAENVRLTETGQPSFRLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMPVEEIATALSEAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGRSAQ
DRGSRTWAVLGKMAELGDESLAEHDAVGRLAVRLNVSKLVAVGDREASWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDIVLVKASRSVGLERVALALLENAAEGEAAGR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgaaatcgtcggcgggcggccgcacgacata
ccggatccggccgtccggatcaccggtccggtcgtcatcgactcccgtgaggtgaagccc
ggcagcctgttcgccgccttcaccggcgagaacgtcgacggccacgactacgcgacgcgc
gccgtcgaggcgggtgcggcggccgtgctggccgcccgccccgtcggcgtgcccgcgatc
gtcgtcgaggacgtccagacggcgctcggggccctcgcccgcgcggtcgtcggccgcctc
gggaccgatgtcgtcgcgctcaccggctcggccggcaagacctccaccaaggacctgatc
gcccaggtcctgcagcggcacgcgcccaccgtgtggacgccgggatcgctcaacaacgag
atcggcctgccgctgaccgcgctcacggcgacggccgaaacccgccacctcgtcctggag
atgggggcgcgcggaatcggccacatccgctacctcaccggcctcaccccgccgcgcatc
ggactcgtcctcaacgtcggcaccgcgcacgtcggcgagttcggcggacgcgagcagatc
gcccaggccaagggcgagctcgtcgaggccctgccggccgccgaggagggcggcatcgcg
gtcctcaacgccgacgacccgctcgtgcgcgccatggcgagccgcaccacggcacgcgtc
accctgttcggagaggcggacgaagcggccgtacgggccgagaacgtccggctcacagaa
accggacagccctctttcaggcttcacacacccaccgggtgcagcgacgtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgcccgtcgaggagatcgccaccgcgctctccgaggcgggcaccctgtcgcgctgg
cgcatggaggtcaccgagcgtccggacggcgtgacgatcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagccgcgctgcgcgcgctcgcggccatgggccggtccgctcag
gaccggggttcccgtacgtgggcggtgctcggcaagatggccgagctcggagacgagtcg
ctcgccgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcggtcggggacagggaagcgtcctggctgcaactgggcgcctataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcaggcggcggtcgacctgttgcgcagtgag
ctgcgcccgggggacatcgtcctggtgaaggcttccaggtcggtgggtctggagcgggtc
gccctggcactgctcgagaacgccgccgagggtgaggcggccggccgatga
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