KEGG   Streptomyces roseirectus: IAG44_32795
Entry
IAG44_32795       CDS       T07860                                 
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
sroi  Streptomyces roseirectus
Pathway
sroi00860  Porphyrin metabolism
sroi01100  Metabolic pathways
sroi01110  Biosynthesis of secondary metabolites
sroi01120  Microbial metabolism in diverse environments
sroi01240  Biosynthesis of cofactors
Module
sroi_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:sroi00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    IAG44_32795 (cobA)
Enzymes [BR:sroi01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     IAG44_32795 (cobA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     IAG44_32795 (cobA)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     IAG44_32795 (cobA)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CofD Radical_SAM 2-Hacid_dh_C COXG DUF3613
Other DBs
NCBI-ProteinID: QNP73771
UniProt: A0A7H0ILV5
LinkDB
Position
7623440..7624672
AA seq 410 aa
MAEHPAYPVGLRLTGRRVVVLGGGQVAQRRLPALIAAGADITLISPTATPSVEAMESAGE
ITWERRPYEPGDLTTAWYALIATNDDAANTRASAEAEANRVWCVRSDDADQATAWTPATG
TSEGVTIAVLTTDAKNRDPRHTARIRDAVLAGLRDGTLVAPHHRTRTPGVSLVGGGPGDP
DLITVRGRRLLAEADVVIADHLGPRDLLAELPPHVEVIDAAKLPYGRYMAQEAINNALIE
HAKAGRSVVRLKGGDPFVYGRGMEEVQALAEAGIPCTVVPGISSSISVPGAAGIPVTHRG
VAQEFTVVSGHVAPDDDRSRIDWSALAKLTGTLVVLMGVDKIGKIAETLIAHGKSPDTPV
ALVQEGTTAAQRRVDATLATVGETARTQEVRPPAVIVIGEVVTVGPRTVA
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggccgaacaccccgcctaccccgtgggcctccgcctcaccggccgccgtgtggtggtc
ctcggcggtggccaggtagcccaacgccgcctcccggccctgatcgcggccggcgcggac
atcacgctgatctccccgaccgcaaccccgtccgtagaggcgatggaatcggcgggcgag
atcacctgggaacgccgcccctacgaacccggcgacctgaccaccgcctggtacgccctg
atcgccacgaacgacgacgcggccaacacccgagcctccgccgaagcggaagcgaaccgc
gtctggtgcgtccgctccgacgacgccgaccaggccaccgcctggaccccggcgaccggc
acgagcgagggcgtcacgatcgccgtcctgacgacggacgcgaagaacagggacccccgc
cacacggcgaggatcagggacgcggtcctggcgggcctgcgcgacggcaccctcgtcgcc
ccccaccaccgcacccgcacccccggcgtctccctggtcggcggcggccccggcgacccg
gacctgatcacggtgcggggccgccgcctcctcgccgaggcggacgtcgtcatcgccgac
cacctcggcccgagggacctcctcgcggaactccccccgcacgtggaggtcatcgacgcc
gcgaagctcccgtacggccgttacatggcccaggaggccatcaacaacgcgctgatcgaa
cacgcgaaggcgggcaggtcggtcgtccggctcaagggcggcgaccccttcgtgtacggc
cggggcatggaggaggtccaggcactcgcggaggccggcatcccctgcacggtcgtcccc
ggcatctccagctccatctcggtccccggcgcggcgggcatccccgtcacgcaccggggt
gtggcccaggagttcacggtcgtcagcggccacgtcgcccccgacgacgaccgctcccgc
atcgactggtccgccctcgcgaagctcaccggcaccctcgtcgtcctcatgggcgtcgac
aagatcggcaagatcgccgagaccctgatcgcccacggcaagtccccggacaccccggtc
gccctggtccaggagggcacgacggccgctcagcgcagggtcgacgccaccctcgcgacg
gtcggcgagacggcccgcacgcaggaggtccgtcccccggcggtgatcgtcatcggcgag
gtcgtcaccgtcggcccccgtaccgtggcgtaa

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