Streptomyces sp. RPA4-5: HEP86_02450
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Entry
HEP86_02450 CDS
T10325
Name
(GenBank) alpha-ketoacid dehydrogenase subunit beta
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
srpa Streptomyces sp. RPA4-5
Pathway
srpa00010
Glycolysis / Gluconeogenesis
srpa00020
Citrate cycle (TCA cycle)
srpa00620
Pyruvate metabolism
srpa00785
Lipoic acid metabolism
srpa01100
Metabolic pathways
srpa01110
Biosynthesis of secondary metabolites
srpa01120
Microbial metabolism in diverse environments
srpa01200
Carbon metabolism
srpa01210
2-Oxocarboxylic acid metabolism
Module
srpa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
srpa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HEP86_02450
00020 Citrate cycle (TCA cycle)
HEP86_02450
00620 Pyruvate metabolism
HEP86_02450
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HEP86_02450
Enzymes [BR:
srpa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HEP86_02450
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Motif
Pfam:
Transketolase_C
Transket_pyr
PFOR_II
Transketolase_C_1
Motif
Other DBs
NCBI-ProteinID:
QIY53554
UniProt:
A0A6H1JSI4
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All DBs
Position
505019..506029
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AA seq
336 aa
AA seq
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MTMVVTRKGSKESETTYREALREALRDALRGDDRVFLMGEDIGRYGGCFGVSLGLLEEFG
PERIRDTPLSESAFVGAGIGAALNGMRPIVEIMTVNFSLLALDQILNNAATLLHMSGGQL
AVPLVIRMTTGAGRQLAAQHSHSLEGWYAHIPGIRVLAPATLDDARYMLAPALADPDPVL
LFEHGSLYNVAGSIGPAPDGAADLDHAAIRRPGTDLSLITYGGSLPKALAAADQLAADGL
SVEVIDLRTLRPLDDATLAASVARTHRAVIVDEAWRTGSLAAEVSARLTEHSFYELDAPV
ERVCSAEVPIPYARQLEEAALPQTADIVAAAHRAVD
NT seq
1011 nt
NT seq
+upstream
nt +downstream
nt
atgacgatggtggtcacccgcaaaggctcgaaagagtcggagacgacgtaccgggaagcc
ctgcgcgaggcgctgcgagatgccttgcgcggcgatgaccgggtctttctcatgggtgag
gacatcgggcggtacggcggctgcttcggcgtcagtctcggcctgttggaggagttcggc
ccggaacgtatccgcgacactccactgtcggagtcggccttcgtaggggcgggcatcggc
gcagccctcaacggtatgcgccccatcgtcgagatcatgacggtgaacttcagcctgctc
gccctcgaccagatcctcaacaacgccgccactttgctgcacatgtccggcggtcagctt
gcggtccctctggtgatccggatgaccaccggcgccggacggcagctggccgcacagcac
tcgcacagccttgagggctggtacgcccacattcccggaatccgcgtcctggcgccggcc
accctcgatgacgcccggtacatgctcgcccccgcacttgcagaccccgacccggtgctg
ctcttcgagcacggcagcctgtacaacgtcgccggctccatcggaccggctcccgacggc
gccgcggacctcgatcacgccgcgatccgcaggcccggcaccgacctctcgctcatcacg
tacgggggatcgctccccaaagcccttgccgcggccgatcagttggccgccgacggcctc
agcgtcgaggtgatcgatctgcgaaccctgcgaccgctcgacgatgcgaccctcgccgcc
tccgtggcccgaacccaccgggcggtgatcgtggacgaggcatggcgcaccggcagtctg
gcggccgaggtttccgctcggctcaccgagcactccttctacgagctggacgctccggta
gagcgcgtatgcagtgcggaagtgccgattccgtacgcccgccagctcgaagaagccgcg
ctcccgcagaccgccgacatcgtcgcggcggcacaccgggcggtggactga
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